Epigenetic mechanisms in cancer. Volume 3 /

Epigenetic Mechanisms in Cancer provides a comprehensive analysis of epigenetic signatures that govern disease development, progression and metastasis. Epigenetic signatures dictating tumor etiologies present an opportunity for biomarker identification which has broad potential for improving diagnos...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Saldanha, Sabita (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London, England : Academic Press, 2018.
Colección:Translational Epigenetics Series
Temas:
Cancer > Genetic aspects.
Epigenetics.
Neoplasms > genetics
Epigenesis, Genetic
Cancer > Aspect g�en�etique.
�Epig�en�etique.
HEALTH & FITNESS / Diseases / General.
MEDICAL / Clinical Medicine.
MEDICAL / Diseases.
MEDICAL / Evidence-Based Medicine.
MEDICAL / Internal Medicine.
Electronic books.
Internet Resources.
Charts.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • ""Front Cover""; ""Epigenetic Mechanisms in Cancer""; ""Translational Epigenetics Series""; ""Epigenetic Mechanisms in Cancer""; ""Copyright""; ""Contents""; ""List of Contributors""; ""1
  • Epigenetic Dysregulation in Pediatric Leukemia""; ""1. INTRODUCTION""; ""2. DNA METHYLATION""; ""2.1 Role of DNA Methylation in Hematopoiesis""; ""2.2 Role in Leukemogenesis""; ""3. HISTONE MODIFICATION""; ""3.1 Role in Hematopoiesis""; ""3.2 Role in Leukemogenesis""; ""4. MICRORNA ALTERATIONS""; ""4.1 Role in Hematopoiesis""; ""4.2 Role in Leukemogenesis""
  • ""5. THERAPEUTIC IMPLICATIONS AND FUTURE DIRECTIONS""""6. CONCLUSION""; ""Acknowledgments""; ""References""; ""2
  • Role of Epigenetics in Testicular Cancer""; ""1. INTRODUCTION""; ""2. TESTICULAR CANCER""; ""2.1 Etiology of the Testicular Germ Cell Tumors""; ""2.1.1 The Testicular Dysgenesis Syndrome""; ""2.1.2 Origin of the Testicular Germ Cell Cancer""; ""2.1.3 The Steroids Receptors""; ""3. EPIGENETIC PROCESSES: FROM NORMAL SPERMATOGENESIS TO TESTICULAR GERM CELL TUMORS""; ""3.1 The Epigenome of Germ Cells and Cancer""; ""3.1.1 DNA Methylation""
  • ""3.1.1.1 DNA Methylation and Testicular Cancer""""3.1.2 Histones Modifications""; ""3.1.2.1 Histone Modifications and Testicular Cancers""; ""3.1.3 Noncoding RNA""; ""3.1.3.1 Noncoding RNA and Testicular Cancers""; ""3.1.4 Repression of Transposable Elements""; ""3.1.4.1 Retrotransponsons and Testicular Cancers""; ""4. THERAPY ISSUES: EPIGENETIC INFLUENCE AND RESISTANCE TO TREATMENT""; ""5. CONCLUSION""; ""List of Acronyms and Abbreviations""; ""Glossary""; ""References""; ""Further Reading""; ""3
  • Changes in the Epigenetic Landscape of Prostate Cancer""; ""1. INTRODUCTION""
  • ""2. EPIGENETICS OF THE BIOLOGY OF THE PROSTATE""""2.1 Physiology of the Prostate""; ""2.2 Racial Differences in Prostate Cancer""; ""3. EPIGENETIC CHANGES IN PROSTATE CANCER""; ""3.1 Prostate Atrophy and Other Early Changes in Prostate Cancer""; ""3.2 Epigenetic Signatures of Prostate Cancer and NGS Technology""; ""3.3 Hormone-Refractory Cancers""; ""4. EPIGENETIC THERAPEUTICS""; ""4.1 Clinical Trials""; ""4.2 Commentary""; ""5. SUMMARY""; ""List of Acronyms and Abbreviations""; ""Glossary""; ""References""; ""4
  • The Genetics and Epigenetics of Colorectal Cancer Health Disparity""
  • ""1. INTRODUCTION""""2. COLORECTAL CANCER TYPES""; ""3. COLORECTAL CANCER GENE-BASED DISPARITY""; ""3.1 P53""; ""3.2 Adenomatous Polyposis Coli Gene (APC)""; ""3.3 Multidrug Resistance 1 (MDR1)""; ""3.4 MutL Homolog1 (MHL1)""; ""4. EPIGENETIC MODIFICATIONS AND COLORECTAL CANCER""; ""4.1 DNA Methylation""; ""4.2 Histone Modifications""; ""4.3 MicroRNAs""; ""5. BIOMARKERS OF COLORECTAL CANCER DIAGNOSIS AND PROGNOSIS""; ""6. CONCLUSION""; ""LIST OF ABBREVIATIONS""; ""Acknowledgments""; ""References""; ""5
  • Genetic and Epigenetic Modifications in Pancreatic Cancer""; ""1. INTRODUCTION""

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