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Cell polarity in development and disease /
Cell Polarity in Development and Disease offers insights into the basic molecular mechanisms of common diseases that arise as a result of a loss of ordered organization and intrinsic polarity. Included are diseases affecting highly polarized epithelial tissues in the lung and kidney, as well as loss...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London, UK :
Academic Press, an imprint of Elsevier,
[2018]
|
| Colección: | Perspectives on translational cell biology series.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 245 | 0 | 0 | |a Cell polarity in development and disease / |c volume editor, Douglas W. Houston. |
| 264 | 1 | |a London, UK : |b Academic Press, an imprint of Elsevier, |c [2018] | |
| 264 | 4 | |c �2018 | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Perspectives in translational cell biology | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Online resource; title from PDF title page (EBSCO, viewed November 9, 2017). | |
| 520 | |a Cell Polarity in Development and Disease offers insights into the basic molecular mechanisms of common diseases that arise as a result of a loss of ordered organization and intrinsic polarity. Included are diseases affecting highly polarized epithelial tissues in the lung and kidney, as well as loss and gain of cell polarity in the onset and progression of cancer. This book provides a basic resource for understanding the biology of polarity, offering a starting point for those thinking of targeting cell polarity for translational medical research. | ||
| 505 | 0 | 0 | |g Machine generated contents note: -- |g 1. |t Cell Polarity in Oocyte Development / |r Douglas W. Houston -- |t Introduction -- |t Oogenesis and the Establishment of Animal -- Vegetal Polarity -- |t Origin of Animal -- Vegetal Polarity During Oogenesis -- |t Xenopus -- |t Zebrafish -- |t Mouse -- |t Polarity and the Ovarian Stem Cell -- |t Structural Basis for Mitochondrial Cloud/Balbiani Formation -- |t Macf1 -- |t Buckyball -- |t Generation of Cortical Polarity in the Oocyte and Egg -- |t Cortical Polarity and Sperm Entry -- |t Apical -- Basal Polarization of the Xenopus Egg -- |t Cortical Polarity and Superficial Cell Fate -- |t Concluding Remarks -- |t Acknowledgments -- |t References -- |g 2. |t Pluripotency -- What Does Cell Polarity Have to Do With It / |r Amy Ralston -- |t Mammalian Pluripotency -- |t Cell Polarity in the Mammalian Embryo -- |t Emergence of Pluripotency in the Mouse Embryo -- |t Cell Polarity in the Mammalian Early Embryo -- |t How Cell Polarity Regulates Establishment of Pluripotency in the Mouse Embryo -- |t Cell Polarity and Embryo-Derived Pluripotent Stem Cell Lines -- |t Multiple States of Pluripotency -- |t Polarization of Pluripotent Stem Cell Lines -- |t Cell Polarization During Somatic Cell Reprogramming -- |t Conclusions -- |t Acknowledgments -- |t References -- |g 3. |t Cell Polarity and Asymmetric Cell Division by the Wnt Morphogen / |r Bryan T. Phillips -- |t Introduction -- |t Binary Cell Fate Specification via Asymmetric Cell Division -- |t PAR Proteins Polarize Caenorhabditis elegans Zygotes -- |t Delta/Notch Signaling Drives Asymmetric Cell Division in Fly Neuroblasts -- |t Morphogens as Cell Polarizers -- |t Wnt/�I²-Catenin Signal Transduction -- |t Wnt/�I²-Catenin Asymmetry and Asymmetric Cell Division in Caenorhabditis elegans -- |t Caenorhabditis elegans Epidermal Seam Stem Cell Lineage Undergoes Reiterative Asymmetric Cell Divisions -- |t Asymmetric Cell Divisions in the Caenorhabditis elegans Seam Require Wnt Signaling -- |t SYS-1/�I²-Catenin Inheritance Is Limited by Centrosomal Degradation -- |t Caenorhabditis elegans/Asymmetric Cell Division-Specific Phenomena -- |t PRY-1/Axin Is Upstream of the Destruction Complex -- |t KIN-19 Versus GSK-3 Function in �I²-Catenin Regulation -- |t Future of Wnt/�I²-Catenin and Asymmetric Cell Division -- |t APR-1 as the Key Regulator of Differential W�I²A Outputs -- |t Dishevelled Balances Wnt/�I²-Catenin Asymmetry Outputs -- |t Wnt Ligands and Receptors -- |t Concluding Remarks -- |t Acknowledgments -- |t References -- |g 4. |t Cell Polarity in Morphogenesis -- Planar Cell Polarity / |r Raymond Habas -- |t Introduction -- |t Planar Cell Polarity Pathway -- |t Wnts -- |t Asymmetric Protein Localization: From Flies to Vertebrates -- |t Role of Cytoskeletal Components During Gastrulation -- |t Actin -- |t Microtubules -- |t Planar Cell Polarity Regulation: Cross Talk Between Cytoskeletal Components -- |t Planar Cell Polarity in Vertebrates -- |t Conclusions -- |t References -- |g 5. |t Polarized Membrane Trafficking in Development and Disease: From Epithelia Polarization to Cancer Cell Invasion / |r Rytis Prekeris -- |t Introduction -- |t Epithelial Polarity and Lumen Formation -- |t Membrane Transport and Polarization of Individual Epithelial Cells -- |t Polarized Membrane Transport and Apical Lumen Formation During Epithelial Tissue Morphogenesis -- |t Regulation of De Novo Lumen Formation In Vivo -- |t Polarized Membrane Transport During Cancer Metastasis and Development -- |t Podosomes and Cell Migration -- |t Invadopodia and Cancer Cell Metastasis -- |t Membrane Transport and MMP Targeting During Invadopodia Formation -- |t Concluding Remarks -- |t Acknowledgments -- |t References -- |g 6. |t Planar Cell Polarity and the Cell Biology of Nervous System Development and Disease / |r J. Robert Manak -- |t Introduction -- |t Breaking the Rules -- |t Effectors of Planar Cell Polarity Genes -- |t Axonal Determination/Polarization: Connections to Polarity Genes -- |t Planar Cell Polarity Mutants Exhibit Axonal Extension Defects -- |t Axonal Extension and the Dynamics of the Cytoskeleton -- |t Lamellipodia and Filopodia Use Different Actin Nucleators -- |t Neuronal Cell Migration Uses the Same Players as During Axonal Polarization -- |t Adherens Junction: A Convergence of Interdependent Signaling Complexes -- |t Focal Adhesions: Reinventing the Adherens Junction for Cellular Movement and Migration -- |t Convergence Extension Defects Leading to Open Neural Tube -- |t Conclusions -- |t Acknowledgments -- |t References -- |g 7. |t Planar Cell Polarity in Ciliated Epithelia / |r Laurent Kodjabachian -- |t Introduction -- |t Initiation and Coordination of Tissue-Level Planar Polarity in Ciliated Epithelia -- |t Xenopus Embryonic Epidermis -- |t Mouse Trachea -- |t Mouse Ependyma -- |t Transmission of Planar Cell Polarity to Basal Bodies in Multiciliated Cells -- |t Xenopus Mucociliary Epidermis -- |t Mouse Trachea -- |t Mouse Ependyma -- |t Future Challenges -- |t General Conclusion -- |t Acknowledgments -- |t References. |
| 650 | 0 | |a Polarity (Biology) | |
| 650 | 0 | |a Cell differentiation. | |
| 650 | 0 | |a Cytology. | |
| 650 | 2 | |a Cell Polarity |0 (DNLM)D016764 | |
| 650 | 2 | |a Morphogenesis |x physiology |0 (DNLM)D009024Q000502 | |
| 650 | 2 | |a Cell Division |0 (DNLM)D002455 | |
| 650 | 2 | |a Cell Differentiation |0 (DNLM)D002454 | |
| 650 | 2 | |a Cell Biology |0 (DNLM)D003585 | |
| 650 | 2 | |a Cytology |0 (DNLM)D000093222 | |
| 650 | 6 | |a Polarit�e (Biologie) |0 (CaQQLa)201-0029995 | |
| 650 | 6 | |a Cellules |x Diff�erenciation. |0 (CaQQLa)201-0030846 | |
| 650 | 6 | |a Cytologie. |0 (CaQQLa)201-0040099 | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Anatomy & Physiology. |2 bisacsh | |
| 650 | 7 | |a Cell differentiation |2 fast |0 (OCoLC)fst00850182 | |
| 650 | 7 | |a Cytology |2 fast |0 (OCoLC)fst00886282 | |
| 650 | 7 | |a Polarity (Biology) |2 fast |0 (OCoLC)fst01068293 | |
| 700 | 1 | |a Houston, Douglas W. |q (Douglas William), |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Cell polarity in development and disease. |d London, UK : Academic Press, an imprint of Elsevier, [2018] |z 9780128024386 |z 0128024380 |w (OCoLC)950450011 |
| 830 | 0 | |a Perspectives on translational cell biology series. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780128024386 |z Texto completo |
| 880 | 0 | 0 | |6 505-00/(S |g Machine generated contents note: |g 1. |t Cell Polarity in Oocyte Development / |r Douglas W. Houston -- |t Introduction -- |t Oogenesis and the Establishment of Animal---Vegetal Polarity -- |t Origin of Animal---Vegetal Polarity During Oogenesis -- |t Xenopus -- |t Zebrafish -- |t Mouse -- |t Polarity and the Ovarian Stem Cell -- |t Structural Basis for Mitochondrial Cloud/Balbiani Formation -- |t Macf1 -- |t Buckyball -- |t Generation of Cortical Polarity in the Oocyte and Egg -- |t Cortical Polarity and Sperm Entry -- |t Apical---Basal Polarization of the Xenopus Egg -- |t Cortical Polarity and Superficial Cell Fate -- |t Concluding Remarks -- |t Acknowledgments -- |t References -- |g 2. |t Pluripotency---What Does Cell Polarity Have to Do With It/ |r Amy Ralston -- |t Mammalian Pluripotency -- |t Cell Polarity in the Mammalian Embryo -- |t Emergence of Pluripotency in the Mouse Embryo -- |t Cell Polarity in the Mammalian Early Embryo -- |t How Cell Polarity Regulates Establishment of Pluripotency in the Mouse Embryo -- |t Cell Polarity and Embryo-Derived Pluripotent Stem Cell Lines -- |t Multiple States of Pluripotency -- |t Polarization of Pluripotent Stem Cell Lines -- |t Cell Polarization During Somatic Cell Reprogramming -- |t Conclusions -- |t Acknowledgments -- |t References -- |g 3. |t Cell Polarity and Asymmetric Cell Division by the Wnt Morphogen / |r Bryan T. Phillips -- |t Introduction -- |t Binary Cell Fate Specification via Asymmetric Cell Division -- |t PAR Proteins Polarize Caenorhabditis elegans Zygotes -- |t Delta/Notch Signaling Drives Asymmetric Cell Division in Fly Neuroblasts -- |t Morphogens as Cell Polarizers -- |t Wnt/β-Catenin Signal Transduction -- |t Wnt/β-Catenin Asymmetry and Asymmetric Cell Division in Caenorhabditis elegans -- |t Caenorhabditis elegans Epidermal Seam Stem Cell Lineage Undergoes Reiterative Asymmetric Cell Divisions -- |t Asymmetric Cell Divisions in the Caenorhabditis elegans Seam Require Wnt Signaling -- |t SYS-1/β-Catenin Inheritance Is Limited by Centrosomal Degradation -- |t Caenorhabditis elegans/Asymmetric Cell Division-Specific Phenomena -- |t PRY-1/Axin Is Upstream of the Destruction Complex -- |t KIN-19 Versus GSK-3 Function in β-Catenin Regulation -- |t Future of Wnt/β-Catenin and Asymmetric Cell Division -- |t APR-1 as the Key Regulator of Differential WβA Outputs -- |t Dishevelled Balances Wnt/β-Catenin Asymmetry Outputs -- |t Wnt Ligands and Receptors -- |t Concluding Remarks -- |t Acknowledgments -- |t References -- |g 4. |t Cell Polarity in Morphogenesis---Planar Cell Polarity / |r Raymond Habas -- |t Introduction -- |t Planar Cell Polarity Pathway -- |t Wnts -- |t Asymmetric Protein Localization: From Flies to Vertebrates -- |t Role of Cytoskeletal Components During Gastrulation -- |t Actin -- |t Microtubules -- |t Planar Cell Polarity Regulation: Cross Talk Between Cytoskeletal Components -- |t Planar Cell Polarity in Vertebrates -- |t Conclusions -- |t References -- |g 5. |t Polarized Membrane Trafficking in Development and Disease: From Epithelia Polarization to Cancer Cell Invasion / |r Rytis Prekeris -- |t Introduction -- |t Epithelial Polarity and Lumen Formation -- |t Membrane Transport and Polarization of Individual Epithelial Cells -- |t Polarized Membrane Transport and Apical Lumen Formation During Epithelial Tissue Morphogenesis -- |t Regulation of De Novo Lumen Formation In Vivo -- |t Polarized Membrane Transport During Cancer Metastasis and Development -- |t Podosomes and Cell Migration -- |t Invadopodia and Cancer Cell Metastasis -- |t Membrane Transport and MMP Targeting During Invadopodia Formation -- |t Concluding Remarks -- |t Acknowledgments -- |t References -- |g 6. |t Planar Cell Polarity and the Cell Biology of Nervous System Development and Disease / |r J. Robert Manak -- |t Introduction -- |t Breaking the Rules -- |t Effectors of Planar Cell Polarity Genes -- |t Axonal Determination/Polarization: Connections to Polarity Genes -- |t Planar Cell Polarity Mutants Exhibit Axonal Extension Defects -- |t Axonal Extension and the Dynamics of the Cytoskeleton -- |t Lamellipodia and Filopodia Use Different Actin Nucleators -- |t Neuronal Cell Migration Uses the Same Players as During Axonal Polarization -- |t Adherens Junction: A Convergence of Interdependent Signaling Complexes -- |t Focal Adhesions: Reinventing the Adherens Junction for Cellular Movement and Migration -- |t Convergence Extension Defects Leading to Open Neural Tube -- |t Conclusions -- |t Acknowledgments -- |t References -- |g 7. |t Planar Cell Polarity in Ciliated Epithelia / |r Laurent Kodjabachian -- |t Introduction -- |t Initiation and Coordination of Tissue-Level Planar Polarity in Ciliated Epithelia -- |t Xenopus Embryonic Epidermis -- |t Mouse Trachea -- |t Mouse Ependyma -- |t Transmission of Planar Cell Polarity to Basal Bodies in Multiciliated Cells -- |t Xenopus Mucociliary Epidermis -- |t Mouse Trachea -- |t Mouse Ependyma -- |t Future Challenges -- |t General Conclusion -- |t Acknowledgments -- |t References. |