The Human microbiome /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, [2017]
Colección:Methods in microbiology ; v. 44.
Temas:
Medical microbiology.
Microorganisms.
Human body > Microbiology.
Molecular microbiology.
Cytology.
Microbiology.
Human Body
Microbiology
Cell Biology
Microbiologie m�edicale.
Micro-organismes.
Microbiologie mol�eculaire.
Cytologie.
Microbiologie.
microorganisms.
microbiology.
HEALTH & FITNESS > Diseases > General.
MEDICAL > Clinical Medicine.
MEDICAL > Diseases.
MEDICAL > Evidence-Based Medicine.
MEDICAL > Internal Medicine.
Internet Resources.
Index not Present.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover
  • The Human Microbiome
  • Copyright
  • Contents
  • Contributors
  • Preface
  • Chapter 1: Bioinformatics in Microbiome Analysis
  • 1. Introduction
  • 2. Bioinformatic Applications for the Analysis of Single Pathogens
  • 3. Bioinformatic Applications for the Analysis of Microbial Communities
  • 3.1. 16S rRNA-Based Approach and Taxonomic Diversity
  • 3.2. Metagenomic Shotgun Sequencing Approach
  • 4. Statistics, Machine Learning and Network Analysis
  • 5. Sequencing Platforms
  • 6. Future Prospective
  • References
  • Further Reading
  • Chapter 2: A Review of the Oesophageal Microbiome in Health and Disease1. Introduction
  • 1.1. Oesophageal Microbiome Composition
  • 1.2. Oesophageal Microbiome Variation Between Individuals
  • 2. Functions of the Oesophageal Microbiome
  • 2.1. Barrier Functions of the Microbiome
  • 2.2. Metabolic Functions of the Microbiome
  • 2.3. Immunomodulation by the Microbiome
  • 2.4. Effects of Gut Microbiome on Host Beyond the Intestinal Tract
  • 3. Oesophageal Microbiome and Disease
  • 3.1. Oesophageal Microbiome and Reflux Disease and Barrett's Oesophagus
  • 3.2. Oesophageal Microbiome and Cancer3.2.1. Microbiome toxin production and cancer
  • 3.2.2. Metabolism and cancer development
  • 3.2.3. Mucin production and cancer
  • 3.2.4. Bystander effect
  • 3.2.5. Role of viruses and oesophageal cancer
  • 4. Future Directions
  • 4.1. Study Design
  • 4.2. Omics Technologies
  • 4.3. Metagenomics
  • 4.4. Metatranscriptomics
  • 4.5. Metaproteomics and Metabolomics
  • Conclusion
  • Acknowledgements
  • References
  • Chapter 3: The Application of Molecular Methods Towards an Understanding of the Role of the Vaginal Microbiome in Health ... 1. Introduction
  • 2. Lactobacillus-Mediated Protection
  • 2.1. Lactobacillus spp. of the Vaginal Microbiome
  • 2.1.1. Adhesion and competitive exclusion
  • 2.1.2. Lactic acid
  • 2.1.3. Bacteriocins
  • 2.1.4. Hydrogen peroxide
  • 2.1.5. Immune modulation
  • 3. The Vaginal Microbiome
  • 3.1. Community State Types
  • 3.2. CST-I: L. crispatus-Dominated Microbiota
  • 3.3. CST-III: L. iners-Dominated Microbiota
  • 3.4. CST-II: L. gasseri- and CST-V: L. jensenii-Dominated Microbiota3.5. CST-IV: Lactobacillus-Depauperate Microbiomes
  • 4. Modulators of the Vaginal Microbiome
  • 4.1. Age and Physiology
  • 4.1.1. Newborn to infancy
  • 4.1.2. Childhood
  • 4.1.3. Adolescence
  • 4.1.4. Reproductive-aged women
  • 4.1.5. Postmenopausal women
  • 4.2. Menses
  • 4.3. Pregnancy
  • 4.4. Host Behaviours
  • 4.5. Sexual Activity
  • 5. Vaginal Dysbiosis and Morbidity
  • Summary and Conclusions
  • References
  • Further Reading

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