The role of neuropeptides in addiction and disorders of excessive consumption /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Thiele, Todd E. (Todd Eric), 1967- (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cambridge, MA : Academic Press, [2017]
Edición:First edition.
Colección:International review of neurobiology ; v. 136.
Temas:
Neuropeptides.
Compulsive behavior.
Neuropeptides
Compulsive Behavior
Comportement compulsif.
addiction.
NATURE > Animals > Mammals.
SCIENCE > Life Sciences > Zoology > Mammals.
Compulsive behavior
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover
  • The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption
  • Copyright
  • Contents
  • Contributors
  • Preface
  • Chapter One: Neuropeptides and Addiction: An Introduction
  • References
  • Chapter Two: Corticotropin-Releasing Factor (CRF) and Addictive Behaviors
  • 1. Introduction
  • 2. CRF Stress Systems
  • 3. CRF, the HPA Axis, and Addiction
  • 4. Extrahypothalamic CRF Systems
  • 5. Role for CRF-CRF1 Systems in Animal Models of Addiction
  • 6. Central Extended Amygdala
  • 6.1. Cellular Mechanisms of CRF
  • 7. Ventral Tegmental Area8. Prefrontal Cortex
  • 9. Compulsive Eating
  • 10. Conclusion
  • Acknowledgments
  • References
  • Chapter Three: Dynorphin/Kappa Opioid Receptor Signaling in Preclinical Models of Alcohol, Drug, and Food Addiction
  • 1. Introduction
  • 1.1. Stress, Addiction, and Kappa Opioid Receptors
  • 1.2. Modulation of Neurotransmitter Signaling by Kappa Opioid Receptors
  • 1.3. Kappa Opioid Receptors in the NAc
  • 1.4. Kappa Opioid Receptors in the VTA
  • 1.5. Measuring Dynorphin Levels
  • 1.6. Opponent Process Theory of Addiction
  • 1.7. Sex Differences in Kappa Opioid Receptor Function2. Ethanol and Kappa Opioid Receptors
  • 2.1. Kappa Opioid Receptors and Ethanol Consumption
  • 2.2. Kappa Opioid Receptors and Chronic Ethanol Exposure
  • 2.3. Ethanol Effects on the Dynorphin/Kappa Opioid Receptor System
  • 2.4. Ethanol, Kappa Opioid Receptors, and Dopamine
  • 3. Cocaine and Kappa Opioid Receptors
  • 3.1. Chronic Stress, Kappa Opioid Receptors, and Cocaine
  • 3.2. Timing of Kappa Opioid Receptor Activation, Dopamine Deficits, and Cocaine Effects
  • 3.3. Kappa Opioid Receptors and DATs
  • 3.4. Cocaine, Kappa Opioid Receptors, and DATs3.5. Reinstatement of Cocaine Self-Administration
  • 4. Obesity and Kappa Opioid Receptors
  • 4.1. The Dynorphin/Kappa Opioid Receptor System and Hereditary Obesity
  • 4.2. Dynorphin/Kappa Opioid Receptor System and Palatable Food Consumption
  • 4.3. Dynorphin/Kappa Opioid Receptor System and Food Deprivation
  • 5. Kappa Opioid Receptor-Based Therapeutics
  • References
  • Further Reading
  • Chapter Four: The Role of the Ghrelin System in Drug Addiction
  • 1. Introduction
  • 2. Ghrelin and Alcohol
  • 2.1. Preclinical Evidence2.2. Clinical Evidence
  • 3. Ghrelin and Stimulants
  • 3.1. Preclinical Evidence
  • 3.2. Clinical Evidence
  • 4. Ghrelin and Tobacco/Nicotine
  • 4.1. Preclinical Evidence
  • 4.2. Clinical Evidence
  • 5. Ghrelin and Opioids
  • 5.1. Preclinical Evidence
  • 6. Ghrelin and Cannabis
  • 6.1. Preclinical Evidence
  • 6.2. Clinical Evidence
  • 7. Conclusions
  • Acknowledgments and Disclosures
  • References
  • Chapter Five: The Role of the Melanocortin System in Drug and Alcohol Abuse
  • 1. Introduction
  • 2. Melanocortin Receptors

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