Bioactive polysaccharides /

Bioactive Polysaccharides offers a comprehensive review of the structures and bioactivities of bioactive polysaccharides isolated from traditional herbs, fungi, and seaweeds. It describes and discusses specific topics based on the authors' rich experience, including extraction technologies, pra...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Nie, Shaoping (Autor), Cui, Steve W. (Autor), Xie, Mingyong (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, �2018.
Temas:
Polysaccharides > Biotechnology.
Polysaccharides.
Polysaccharides
Polysaccharides > Biotechnologie.
SCIENCE > Life Sciences > Biochemistry.
Polysaccharides > Biotechnology
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover
  • Bioactive Polysaccharides
  • Copyright Page
  • Contents
  • Preface
  • 1 Introduction
  • 1.1 Definition of Polysaccharides and Their Research History
  • 1.2 Overview of the Structure of Polysaccharide, and Structural Diversity
  • 1.3 Overview on Bioactivities
  • 1.3.1 Anticancer
  • 1.3.2 Immunoregulation
  • 1.3.3 Antidiabetics and Kidney Repair
  • 1.3.4 Antioxidant
  • 1.3.5 Antiinflammatory
  • 1.3.6 Other
  • 1.4 The Structure�a#x88;#x92;Bioactivity Relationship of Polysaccharides
  • 1.4.1 Viscosity
  • 1.4.2 Molecular Weight
  • 1.4.3 Conformation
  • 1.4.4 Substituent Group1.4.4.1 Sulfate Group
  • 1.4.4.2 Carboxymethyl Group
  • 1.4.4.3 Other Substitution Groups
  • 1.5 Perspectives
  • References
  • 2 Methodologies for Studying Bioactive Polysaccharides
  • 2.1 Isolation, Purification, and Characterization
  • 2.2 Structural Analysis
  • 2.2.1 Chemical Methods
  • 2.2.1.1 Methanolysis
  • 2.2.1.2 Acetolysis
  • 2.2.1.3 Periodate Oxidation and Smith Degradation
  • 2.2.1.4 Methylation Analysis
  • 2.2.2 Instrumental Methods
  • 2.2.2.1 UV-Vis Spectrophotometry and FTIR Spectroscopy
  • 2.2.2.2 Chromatography and Mass Spectroscopy2.2.2.2.1 GC and HPLC
  • 2.2.2.2.2 Mass Spectroscopy
  • 2.2.2.2.3 FAB-MS
  • 2.2.2.2.4 ESI-MS
  • 2.2.2.2.5 MALDI-TOF
  • 2.2.2.3 NMR Spectroscopy
  • 2.2.2.3.1 Liquid-State NMR
  • 2.2.2.3.2 Solid-State NMR
  • 2.2.3 Biological Methods
  • 2.3 Conformations
  • 2.3.1 Light Scattering
  • 2.3.2 Molecular Modeling
  • 2.3.2.1 Force Fields
  • 2.3.2.2 Minimization of Molecules
  • 2.4 Animal Studies and Clinical Trials
  • 2.4.1 Animal Models
  • 2.4.2 Clinical Trials
  • 2.4.2.1 Tissue Engineering
  • 2.4.2.2 Wound Healing and Wound Dressing2.4.2.3 Drug Delivery and Controlled Release
  • 2.4.2.4 Treatment of Cancer
  • 2.5 Cell Culture: Action of Mechanism�a#x88;#x92;Polysaccharide�a#x88;#x92;Receptors Interactions
  • 2.5.1 Natural Killer Group 2D
  • 2.5.2 TGF-�I² Receptors
  • 2.5.3 Toll-Like Receptor 4
  • 2.5.4 Toll-Like Receptor 2
  • 2.5.5 CD14
  • 2.5.6 Dectin-1
  • 2.5.7 Dectin-2
  • 2.5.8 The Mannose Receptor
  • 2.5.9 Scavenger Receptors
  • 2.5.10 CD19 and CD79
  • 2.5.11 Complement Receptor 3 (CR3)
  • 2.5.12 Membrane Immunoglobulins
  • 2.5.13 Receptor Protein 105/Myeloid Differentiation-1References
  • 3 Beta-Glucans and Their Derivatives
  • 3.1 Sources
  • 3.1.1 Beta-Glucan From Fungi
  • 3.1.2 Beta-Glucan From Bacteria
  • 3.1.3 Beta-Glucan From Plants and Algae
  • 3.2 Preparation, Extraction, and Purification
  • 3.2.1 Hot-Water Extraction
  • 3.2.2 Ultrasound-Assisted Extraction and Microwave-Assisted Extraction
  • 3.2.3 Purification of Beta-Glucan
  • 3.3 Structural Features
  • 3.4 Molecular Characteristics
  • 3.5 Bioactivities
  • 3.5.1 Immune-Enhancement and Antitumor Effects

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