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Bioactive polysaccharides /
Bioactive Polysaccharides offers a comprehensive review of the structures and bioactivities of bioactive polysaccharides isolated from traditional herbs, fungi, and seaweeds. It describes and discusses specific topics based on the authors' rich experience, including extraction technologies, pra...
| Clasificación: | Libro Electrónico |
|---|---|
| Autores principales: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Academic Press,
�2018.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 005 | 20231120010224.0 | ||
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| 008 | 171018s2018 enka ob 001 0 eng d | ||
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| 020 | |a 0128114517 |q (electronic bk.) | ||
| 020 | |z 0128094184 | ||
| 020 | |z 9780128094181 | ||
| 035 | |a (OCoLC)1006584315 |z (OCoLC)1006502607 |z (OCoLC)1066411418 |z (OCoLC)1235829069 | ||
| 050 | 4 | |a QP702.P6 | |
| 060 | 4 | |a 2018 B-910 | |
| 060 | 4 | |a QU 83 | |
| 072 | 7 | |a SCI |x 007000 |2 bisacsh | |
| 082 | 0 | 4 | |a 572.566 |2 23 |
| 100 | 1 | |a Nie, Shaoping, |e author. | |
| 245 | 1 | 0 | |a Bioactive polysaccharides / |c Shaoping Nie, Steve W. Cui, Mingyong Xie. |
| 260 | |a London : |b Academic Press, |c �2018. | ||
| 300 | |a 1 online resource : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 500 | |a Includes index. | ||
| 505 | 0 | |6 880-01 |a Front Cover -- Bioactive Polysaccharides -- Copyright Page -- Contents -- Preface -- 1 Introduction -- 1.1 Definition of Polysaccharides and Their Research History -- 1.2 Overview of the Structure of Polysaccharide, and Structural Diversity -- 1.3 Overview on Bioactivities -- 1.3.1 Anticancer -- 1.3.2 Immunoregulation -- 1.3.3 Antidiabetics and Kidney Repair -- 1.3.4 Antioxidant -- 1.3.5 Antiinflammatory -- 1.3.6 Other -- 1.4 The Structure�a#x88;#x92;Bioactivity Relationship of Polysaccharides -- 1.4.1 Viscosity -- 1.4.2 Molecular Weight -- 1.4.3 Conformation | |
| 505 | 8 | |a 1.4.4 Substituent Group1.4.4.1 Sulfate Group -- 1.4.4.2 Carboxymethyl Group -- 1.4.4.3 Other Substitution Groups -- 1.5 Perspectives -- References -- 2 Methodologies for Studying Bioactive Polysaccharides -- 2.1 Isolation, Purification, and Characterization -- 2.2 Structural Analysis -- 2.2.1 Chemical Methods -- 2.2.1.1 Methanolysis -- 2.2.1.2 Acetolysis -- 2.2.1.3 Periodate Oxidation and Smith Degradation -- 2.2.1.4 Methylation Analysis -- 2.2.2 Instrumental Methods -- 2.2.2.1 UV-Vis Spectrophotometry and FTIR Spectroscopy | |
| 505 | 8 | |a 2.2.2.2 Chromatography and Mass Spectroscopy2.2.2.2.1 GC and HPLC -- 2.2.2.2.2 Mass Spectroscopy -- 2.2.2.2.3 FAB-MS -- 2.2.2.2.4 ESI-MS -- 2.2.2.2.5 MALDI-TOF -- 2.2.2.3 NMR Spectroscopy -- 2.2.2.3.1 Liquid-State NMR -- 2.2.2.3.2 Solid-State NMR -- 2.2.3 Biological Methods -- 2.3 Conformations -- 2.3.1 Light Scattering -- 2.3.2 Molecular Modeling -- 2.3.2.1 Force Fields -- 2.3.2.2 Minimization of Molecules -- 2.4 Animal Studies and Clinical Trials -- 2.4.1 Animal Models -- 2.4.2 Clinical Trials -- 2.4.2.1 Tissue Engineering | |
| 505 | 8 | |a 2.4.2.2 Wound Healing and Wound Dressing2.4.2.3 Drug Delivery and Controlled Release -- 2.4.2.4 Treatment of Cancer -- 2.5 Cell Culture: Action of Mechanism�a#x88;#x92;Polysaccharide�a#x88;#x92;Receptors Interactions -- 2.5.1 Natural Killer Group 2D -- 2.5.2 TGF-�I² Receptors -- 2.5.3 Toll-Like Receptor 4 -- 2.5.4 Toll-Like Receptor 2 -- 2.5.5 CD14 -- 2.5.6 Dectin-1 -- 2.5.7 Dectin-2 -- 2.5.8 The Mannose Receptor -- 2.5.9 Scavenger Receptors -- 2.5.10 CD19 and CD79 -- 2.5.11 Complement Receptor 3 (CR3) -- 2.5.12 Membrane Immunoglobulins | |
| 505 | 8 | |a 2.5.13 Receptor Protein 105/Myeloid Differentiation-1References -- 3 Beta-Glucans and Their Derivatives -- 3.1 Sources -- 3.1.1 Beta-Glucan From Fungi -- 3.1.2 Beta-Glucan From Bacteria -- 3.1.3 Beta-Glucan From Plants and Algae -- 3.2 Preparation, Extraction, and Purification -- 3.2.1 Hot-Water Extraction -- 3.2.2 Ultrasound-Assisted Extraction and Microwave-Assisted Extraction -- 3.2.3 Purification of Beta-Glucan -- 3.3 Structural Features -- 3.4 Molecular Characteristics -- 3.5 Bioactivities -- 3.5.1 Immune-Enhancement and Antitumor Effects | |
| 520 | |a Bioactive Polysaccharides offers a comprehensive review of the structures and bioactivities of bioactive polysaccharides isolated from traditional herbs, fungi, and seaweeds. It describes and discusses specific topics based on the authors' rich experience, including extraction technologies, practical techniques required for purification and fractionation, strategies and skills for elucidating the fine structures, in-vitro and in-vivo protocols, and methodologies for evaluating the specific bioactivities, including immune-modulating activities, anti-cancer activities, anti-oxidant activities, and others. This unique book also discusses partial structure-functionality (bioactivities) relationships based on conformational studies. This comprehensive work can be used as a handbook to explore potential applications in foods, pharmaceuticals, and nutraceutical areas for commercial interests. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 650 | 0 | |a Polysaccharides |x Biotechnology. | |
| 650 | 0 | |a Polysaccharides. | |
| 650 | 1 | 2 | |a Polysaccharides |0 (DNLM)D011134 |
| 650 | 6 | |a Polysaccharides |0 (CaQQLa)201-0011180 |x Biotechnologie. |0 (CaQQLa)201-0378829 | |
| 650 | 6 | |a Polysaccharides. |0 (CaQQLa)201-0011180 | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Biochemistry. |2 bisacsh | |
| 650 | 7 | |a Polysaccharides |2 fast |0 (OCoLC)fst01070795 | |
| 650 | 7 | |a Polysaccharides |x Biotechnology |2 fast |0 (OCoLC)fst01070797 | |
| 700 | 1 | |a Cui, Steve W., |e author. | |
| 700 | 1 | |a Xie, Mingyong, |e author. | |
| 776 | 0 | 8 | |i Print version: |z 0128094184 |z 9780128094181 |w (OCoLC)962355154 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780128094181 |z Texto completo |
| 880 | 0 | 0 | |6 505-01/(S |g Machine generated contents note: |g 1. |t Introduction -- |g 1.1. |t Definition of Polysaccharides and Their Research History -- |g 1.2. |t Overview of the Structure of Polysaccharide, and Structural Diversity -- |g 1.3. |t Overview on Bioactivities -- |g 1.3.1. |t Anticancer -- |g 1.3.2. |t Immunoregulation -- |g 1.3.3. |t Antidiabetics and Kidney Repair -- |g 1.3.4. |t Antioxidant -- |g 1.3.5. |t Antiinflammatory -- |g 1.3.6. |t Other -- |g 1.4. |t Structure --- Bioactivity Relationship of Polysaccharides -- |g 1.4.1. |t Viscosity -- |g 1.4.2. |t Molecular Weight -- |g 1.4.3. |t Conformation -- |g 1.4.4. |t Substituent Group -- |g 1.5. |t Perspectives -- |t References -- |g 2. |t Methodologies for Studying Bioactive Polysaccharides -- |g 2.1. |t Isolation, Purification, and Characterization -- |g 2.2. |t Structural Analysis -- |g 2.2.1. |t Chemical Methods -- |g 2.2.2. |t Instrumental Methods -- |g 2.2.3. |t Biological Methods -- |g 2.3. |t Conformations -- |g 2.3.1. |t Light Scattering -- |g 2.3.2. |t Molecular Modeling -- |g 2.4. |t Animal Studies and Clinical Trials -- |g 2.4.1. |t Animal Models -- |g 2.4.2. |t Clinical Trials -- |g 2.5. |t Cell Culture: Action of Mechanism --- Polysaccharide --- Receptors Interactions -- |g 2.5.1. |t Natural Killer Group 2D -- |g 2.5.2. |t TGF-β Receptors -- |g 2.5.3. |t Toll-Like Receptor 4 -- |g 2.5.4. |t Toll-Like Receptor 2 -- |g 2.5.5. |t CD14 -- |g 2.5.6. |t Dectin-1 -- |g 2.5.7. |t Dectin-2 -- |g 2.5.8. |t Mannose Receptor -- |g 2.5.9. |t Scavenger Receptors -- |g 2.5.10. |t CD19 and CD79 -- |g 2.5.11. |t Complement Receptor 3 (CR3) -- |g 2.5.12. |t Membrane Immunoglobulins -- |g 2.5.13. |t Receptor Protein 105/Myeloid Differentiation-1 -- |t References -- |g 3. |t Beta-Glucans and Their Derivatives -- |g 3.1. |t Sources -- |g 3.1.1. |t Beta-Glucan From Fungi -- |g 3.1.2. |t Beta-Glucan From Bacteria -- |g 3.1.3. |t Beta-Glucan From Plants and Algae -- |g 3.2. |t Preparation, Extraction, and Purification -- |g 3.2.1. |t Hot-Water Extraction -- |g 3.2.2. |t Ultrasound-Assisted Extraction and Microwave-Assisted Extraction -- |g 3.2.3. |t Purification of Beta-Glucan -- |g 3.3. |t Structural Features -- |g 3.4. |t Molecular Characteristics -- |g 3.5. |t Bioactivities -- |g 3.5.1. |t Immune-Enhancement and Antitumor Effects -- |g 3.5.2. |t Antihypocholesterolemic and Antihpyerglycemic Effects -- |g 3.5.3. |t Antioxidant Activity -- |g 3.5.4. |t Antimicrobial and Antiviral Effects -- |g 3.6. |t Discussion: Structure---Bioactivity Relationship -- |g 3.6.1. |t Conformation -- |g 3.6.2. |t Molecular Weight and Solubility -- |g 3.6.3. |t Carboxymethylation -- |g 3.6.4. |t Sulfation -- |g 3.6.5. |t Other Chemical Modifications -- |t References -- |g 4. |t Cordyceps Polysaccharides -- |g 4.1. |t Harvesting and Preparation -- |g 4.1.1. |t Polysaccharide Content in Cordyceps -- |g 4.1.2. |t Isolation and Purification of Polysaccharide in Cordyceps -- |g 4.2. |t Structural Features -- |g 4.2.1. |t Cordyceps sinensis -- |g 4.2.2. |t Cordyceps militaris -- |g 4.2.3. |t Cordyceps gunii -- |g 4.2.4. |t Other Cordyceps species -- |g 4.3. |t Molecular Characteristics -- |g 4.4. |t Bioactivities -- |g 4.4.1. |t Protective Effects on the Kidney -- |g 4.4.2. |t Immunomodulatory Activity -- |g 4.4.3. |t Antioxidant Activity -- |g 4.4.4. |t Hypoglycemic Effect -- |g 4.4.5. |t Anti-Tumor Activity -- |g 4.4.6. |t Protective Effect on Liver Disease -- |g 4.4.7. |t Anti-Platelet Effect -- |g 4.4.8. |t Antimutagenic Effect -- |g 4.4.9. |t Longevity and Anti-Aging -- |g 4.4.10. |t Other Activity -- |g 4.5. |t Discussion: Structure---Bioactivity Relationship -- |t References -- |g 5. |t Complex Glucomannan From Ganoderma atrum -- |g 5.1. |t Preparation and Structural Characterization -- |g 5.1.1. |t Isolation of PSG-1 -- |g 5.1.2. |t Chemical Analysis of PSG-1 -- |g 5.1.3. |t Structural Features of PSG-1 -- |g 5.2. |t Bioactivities -- |g 5.2.1. |t Immunomodulatory -- |g 5.2.2. |t Anti-Tumor -- |g 5.2.3. |t Anti-Diabetes -- |g 5.3. |t Structure---Bioactivity Relationship -- |g 5.3.1. |t Acetylation and Carboxymethylation of the Polysaccharide From PSG-1 -- |g 5.3.2. |t Antioxidant Activity -- |g 5.3.3. |t Immunomodulatory Activity -- |g 5.3.4. |t Relationship Between Structure and Bioactivity of PSG -- |t References -- |g 6. |t Glucomannans From Dendrobium officinale and Aloe -- |g 6.1. |t Introduction -- |g 6.1.1. |t Dendrobium Herbs and Dendrobium officinale -- |g 6.1.2. |t Introduction of Aloe -- |g 6.2. |t Preparation Process -- |g 6.2.1. |t Preparation Process for Dendronan -- |g 6.2.2. |t Preparation Process for Acemannan -- |g 6.3. |t Structural Features -- |g 6.3.1. |t Structural Features of Dendronan -- |g 6.3.2. |t Structures of Acemannan -- |g 6.4. |t Chemical Modifications -- |g 6.4.1. |t Chemical Modifications of Dendronan -- |g 6.4.2. |t Chemical Modifications of Acemannan -- |g 6.5. |t Bioactivities -- |g 6.5.1. |t Bioactivities of Dendronan -- |g 6.5.2. |t Bioactivities of Acemannan -- |g 6.6. |t Discussion: Structure---Bioactivity Relationship -- |t References -- |g 7. |t Tea Polysaccharide -- |g 7.1. |t Introduction -- |g 7.2. |t Extraction Methods -- |g 7.3. |t Physicochemical and Structural Features -- |g 7.4. |t Chemical Modification of Tea Polysaccharides -- |g 7.5. |t Bioactivity of Tea Polysaccharides -- |g 7.5.1. |t Hypoglycemic Effect -- |g 7.5.2. |t Hypolipidemic and Antiatherogenic Effects -- |g 7.5.3. |t Anticoagulant and Antithrombotic Effects -- |g 7.5.4. |t Lowering Blood Pressure, Hypoxia Tolerance, and Increasing the Flow of Coronary Blood -- |g 7.5.5. |t Immunomodulatory Activity -- |g 7.5.6. |t Anticancer and Antitumor Activities -- |g 7.5.7. |t Antioxidation -- |g 7.5.8. |t Radiation Protection -- |g 7.5.9. |t Skin Care -- |g 7.5.10. |t Toxicity -- |g 7.5.11. |t Antifatigue Activity -- |g 7.5.12. |t Hepatoprotective Effects -- |g 7.5.13. |t Benefits on Gastrointestinal Function -- |g 7.5.14. |t Other Bioactivity -- |g 7.6. |t Structure---Function Relationship -- |g 7.7. |t Summary -- |t References -- |g 8. |t Psyllium Polysaccharide -- |g 8.1. |t Preparation Process -- |g 8.2. |t Structural Features -- |g 8.3. |t Molecular Characteristics -- |g 8.4. |t Bioactivities -- |g 8.4.1. |t Laxative Effect -- |g 8.4.2. |t Therapy for Intestinal Diseases -- |g 8.4.3. |t Intestinal Function Activity -- |g 8.4.4. |t Hypoglycemic Effect -- |g 8.4.5. |t Hypocholesterolemic Effect -- |g 8.4.6. |t Antitumor Effect -- |g 8.4.7. |t Immune Enhancement Effect -- |g 8.4.8. |t Other Activities -- |g 8.4.9. |t Possible Adverse Effects: Anaphylaxis, Rhinitis, and Asthma -- |g 8.5. |t Discussion: Structure---Bioactivity Relationship -- |g 8.5.1. |t Viscosity -- |g 8.5.2. |t Structural Modifications -- |g 8.6. |t Applications -- |g 8.6.1. |t Food Industry and Dietary Fiber Supplements -- |g 8.6.2. |t Drug Delivery Systems -- |g 8.6.3. |t Wastewater Treatment -- |g 8.6.4. |t Other Applications -- |t References -- |g 9. |t Cereal Beta-Glucan -- |g 9.1. |t Introduction -- |g 9.2. |t Extraction and Structural Characterization -- |g 9.2.1. |t Solubility and Extractability -- |g 9.2.2. |t Solubility of Freeze-Dried β-D-Glucan Samples -- |g 9.2.3. |t Structural Characterizations of Cereal Beta-Glucans -- |g 9.2.4. |t Structural Features -- |g 9.3. |t Molecular Weight, Conformation, and Rheological Properties -- |g 9.3.1. |t Molecular Weight Determination -- |g 9.3.2. |t Solution and Conformational Properties -- |g 9.3.3. |t Rheology: Viscoelastic and Gelling Properties -- |g 9.4. |t Bioactivities and Health Benefits -- |g 9.4.1. |t Beta-D-Glucan and Blood Glucose -- |g 9.4.2. |t Beta-D-Glucan and Cholesterol Levels -- |g 9.4.3. |t Fermentation Properties and Gut Health and Other Bioactivities -- |g 9.5. |t Summary -- |t References -- |t Further Reading -- |g 10. |t Other Herbal Polysaccharides -- |g 10.1. |t Sources and Preparation -- |g 10.1.1. |t Panax ginseng Polysaccharide -- |g 10.1.2. |t Angelica sinensis Polysaccharide -- |g 10.1.3. |t Lycium barbarum Polysaccharide -- |g 10.1.4. |t Astragalus Polysaccharides -- |g 10.2. |t Structural Features -- |g 10.2.1. |t Panax ginseng Polysaccharide -- |g 10.2.2. |t Angelica sinensis Polysaccharide -- |g 10.2.3. |t Lycium barbarum Polysaccharide -- |g 10.2.4. |t Astragalus Polysaccharide -- |g 10.3. |t Bioactivities -- |g 10.3.1. |t Panax ginseng Polysaccharide -- |g 10.3.2. |t Angelica sinensis Polysaccharide -- |g 10.3.3. |t Lycium barbarum Polysaccharide -- |g 10.3.4. |t Astragalus Polysaccharide -- |g 10.4. |t Summary -- |t References -- |g 11. |t Practical Applications of Bioactive Polysaccharides -- |g 11.1. |t Bioactive Polysaccharides as Clinical Drugs and Medicines -- |g 11.1.1. |t Anticancer Drugs -- |g 11.1.2. |t Immunomodulatory Drugs. |