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Role of nutraceuticals in cancer chemosensitization /
Role of Nutraceuticals in Chemoresistance to Cancer, Volume Two, focuses on nutraceuticals, the compounds derived from natural sources, which are usually multi-targeted as a means to overcome chemoresistance. This book discusses the role of several compounds related to nutraceuticals and chemoresist...
| Clasificación: | Libro Electrónico |
|---|---|
| Autores principales: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London, United Kingdom :
Academic Press,
[2018]
|
| Edición: | First edition. |
| Colección: | Cancer sensitizing agents for chemotherapy ;
v. 2. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 100 | 1 | |a Bharti, Alok Chandra, |e author. | |
| 245 | 1 | 0 | |a Role of nutraceuticals in cancer chemosensitization / |c Alok Chandra Bharti, Bharat Bhushan Aggarwal. |
| 250 | |a First edition. | ||
| 264 | 1 | |a London, United Kingdom : |b Academic Press, |c [2018] | |
| 264 | 4 | |c �2018 | |
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| 490 | 1 | |a Cancer sensitizing agents for chemotherapy ; |v volume 2 | |
| 588 | 0 | |a Vendor-supplied metadata. | |
| 500 | |a Includes index. | ||
| 520 | |a Role of Nutraceuticals in Chemoresistance to Cancer, Volume Two, focuses on nutraceuticals, the compounds derived from natural sources, which are usually multi-targeted as a means to overcome chemoresistance. This book discusses the role of several compounds related to nutraceuticals and chemoresistance, such as curcumin, resveratrol, indole 3-carbinol, tocotrienols, ursolic acid, fisetin, celastrol, gambogic, butein, catechins and silymarin. It is a valuable resource for cancer researchers, oncologists and members of several areas of the biomedical field who are interested in understanding how to use nutraceuticals as a sensitizing agent for chemotherapy. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Front Cover -- Cancer Sensitizing Agents for Chemotherapy: Role of Nutraceuticals in Cancer Chemosensitization -- Copyright -- Contents -- Contributors -- About the Editors -- About the Series Editor -- Aims and Scope for Series �a#x80;Cancer Sensitizing Agents for Chemotherapy�a#x80;#x9D; -- Preface -- Chapter 1: Pathways Linked to Cancer Chemoresistance and Their Targeting by Nutraceuticals -- Introduction -- Chemotherapy -- Alkylating Agents -- Cell Cycle Inhibitors/Antimicrotubule Agents -- Antimetabolites -- Antibiotics -- Topoisomerase Inhibitors | |
| 505 | 8 | |a Targeted TherapyTarget-Specific Antibodies -- Small Molecule Inhibitors -- Chemoresistance: Problem in Curing Cancer -- Mechanism of Chemoresistance -- Drug Transporters -- Enhanced DNA Repair System -- Drug Inactivation -- Altered Drug Targets -- Epithelial-Mesenchymal Transition -- Inhibition of Apoptosis -- Autophagy -- Aberrant Expression and Constitutive Activation of Transcription Factors -- Nuclear Factor-Kappa B (NF-�I�B) -- Signal Transducers and Activators of Transcription 3 (STAT-3) -- Activating Protein-1 (AP-1) | |
| 505 | 8 | |a Activation of Self-Renewal PathwaysChemosensitization: An Approach to Target Cancer -- Nutraceuticals as Chemosensitizers: Opportunities and Challenges -- Conclusion -- Conflict of Interest -- Acknowledgments -- References -- Chapter 2: The Potential of Curcumin: A Multitargeting Agent in Cancer Cell Chemosensitization -- Introduction -- Molecular Targets of Curcumin -- Chemosensitization Studies of Curcumin in Different Cancers -- Curcumin Mediated Chemosensitization in Bladder Cancer -- Curcumin Mediated Chemosensitization in Brain Cancer | |
| 505 | 8 | |a Curcumin Mediated Chemosensitization in Breast CancerCurcumin Mediated Chemosensitization in Cervical Cancer -- Curcumin Mediated Chemosensitization in Colon Cancer -- Curcumin Mediated Chemosensitization in Esophageal Cancer -- Curcumin Mediated Chemosensitization in Leukemia -- Curcumin Mediated Chemosensitization in Lung Cancer -- Curcumin Mediated Chemosensitization in Multiple Myeloma -- Curcumin Mediated Chemosensitization in Ovarian Cancer -- Curcumin Mediated Chemosensitization in Pancreatic Cancer -- Curcumin Mediated Chemosensitization in Prostate Cancer | |
| 505 | 8 | |a Curcumin Mediated Chemosensitization in Other CancersHybrid Curcumin -- Conclusion -- Conflict of Interest -- Acknowledgment -- References -- Further Reading -- Chapter 3: Role of Resveratrol in Chemosensitization of Cancer -- Introduction -- Source and Chemistry of Resveratrol -- Possible Molecular Mechanisms of Chemoresistance in Cancer -- ATP-Dependent Drug Efflux -- Drug Detoxification -- Alterations in Drug Target Molecules -- Alterations in DNA Damage Repair Pathways -- Regulation of Cell Cycle Arrest -- Regulation of Apoptosis | |
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