Cargando…
Cancer and noncoding RNAs. Volume 1 /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Academic Press, an imprint of Elsevier,
[2017]
|
| Colección: | Translational epigenetics series.
|
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover
- Cancer and Noncoding RNAs
- Series Page
- Cancer and Noncoding RNAs
- Copyright
- Contents
- List of Contributors
- 1
- INTRODUCTION
- CANCER: THE CRAB
- TYPES OF CANCER
- TUMOR, NODE, METASTASIS STAGING OF CANCER
- PRIMARY TUMOR (T)
- REGIONAL LYMPH NODES (N)
- DISTANT METASTASIS (M)
- MOLECULAR DELINEATION OF CANCER
- GENETIC ALTERATION SIGNATURES IN CANCER
- COMPETING ENDOGENOUS RNAS HYPOTHESIS
- EPIGENETIC ALTERATION SIGNATURES IN CANCER
- THERAPEUTIC POTENTIAL OF NONCODING RNA IN CANCER
- REFERENCES
- 1
- NON-CODING RNAs: FINE-TUNING CANCER2
- MIRNA AND CANCER: A DEADLY LIAISON?
- INTRODUCTION
- CELL CYCLE, PROLIFERATION, AND SURVIVAL
- ANGIOGENESIS AND METASTASIS
- TUMOR MICROENVIRONMENT
- CANCER STEM CELLS AND CHEMORESISTANCE
- PERSPECTIVE
- ACKNOWLEDGMENTS
- REFERENCES
- 3
- ALTERATION OF MICRORNA BIOGENESIS PATHWAYS IN CANCERS
- INTRODUCTION
- MICRORNA BIOGENESIS PATHWAY IN ANIMALS
- ALTERATION IN MICRORNA TRANSCRIPTION
- ALTERATION IN PRIMARY MICRORNA PROCESSING IN NUCLEUS
- ALTERATION IN PRE-MICRORNA EXPORT INTO CYTOPLASM
- ALTERATION IN CYTOPLASMIC PRE-MICRORNA PROCESSINGALTERATION IN RNA-INDUCED SILENCING COMPLEX
- CONCLUSION
- REFERENCES
- 4
- MICRORNAS IN EXOSOMES IN CANCER
- CHAPTER OVERVIEW
- INTRODUCTION TO MICRORNAS
- BRIEF DESCRIPTION OF CANONICAL MICRORNA BIOGENESIS
- BRIEF DESCRIPTION OF MICRORNA FUNCTION
- BRIEF DESCRIPTION OF EXOSOMES
- BRIEF DESCRIPTION OF EXOSOMAL SORTING OF MICRORNAS
- EXOSOMAL MICRORNA IN CANCER�a#x80;#x94;INVASION AND METASTASIS
- EXOSOMAL MICRORNA IN CANCER�a#x80;#x94;ANGIOGENESIS
- EXOSOMAL MICRORNAS IN CANCER�a#x80;#x94;REGULATING METABOLISM
- EXOSOMAL MICRORNA IN CANCER�a#x80;#x94;CROSS TALK WITH THE IMMUNE SYSTEMEXOSOMAL MICRORNA IN CANCER�a#x80;#x94;CHEMORESISTANCE AND CHEMOSENSITIVITY
- EXOSOMAL MICRORNA IN CANCER�a#x80;#x94;POTENTIAL BIOMARKERS AND LIQUID BIOPSY
- EXOSOMAL MICRORNA IN CANCER�a#x80;#x94;CONCLUSION
- LIST OF ACRONYMS AND ABBREVIATIONS
- GLOSSARY
- REFERENCES
- 5
- CIRCULATING MIRNAS INCREASING THE RISK OF CANCER
- INTRODUCTION
- HOW CIRCULATING MIRNAS ARE FOUND IN BLOOD SAMPLES
- DISCOVERY OF CIRCULATING MIRNA
- EXTRACELLULAR MIRNA
- WHY CIRCULATING MIRNAS ARE BECOMING AN INCREASING RISK
- CIRCULATING MIRNA IS ABLE TO SHUTTLE BETWEEN DIFFERENT CELLSSECRETED MIRNAS CAN SERVE AS SIGNALING MOLECULES MEDIATING INTERCELLULAR COMMUNICATION
- CIRCULATING MIRNAS CAN BE USED AS AN EARLY DETECTION TECHNIQUE
- THE DIAGNOSTIC POTENTIAL OF MIRNAS IN VARIOUS CANCERS
- Lung Cancer
- Breast Cancer
- Colorectal Cancer
- Gastric Cancer
- Other Cancers
- CHALLENGES IN UTILIZING MIRNAS AS CIRCULATING BIOMARKERS
- THE THERAPEUTIC IMPLICATIONS OF MIRNAS
- CONCLUSION AND FUTURE PERSPECTIVES
- REFERENCES
- 6
- LONG NONCODING RNAS AS CANCER BIOMARKERS
- ""INTRODUCTION: �a#x80;#x9C;JUNK DNA, �a#x80;#x9D; THE NEW KEY PLAYER IN DEVELOPMENT AND DISEASE""