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019 |a 1004960768  |a 1005188732  |a 1105170373  |a 1105560517  |a 1235845030 
020 |a 9780081008522  |q (electronic bk.) 
020 |a 008100852X  |q (electronic bk.) 
020 |z 0081008031 
020 |z 9780081008034 
035 |a (OCoLC)1005124803  |z (OCoLC)1004960768  |z (OCoLC)1005188732  |z (OCoLC)1105170373  |z (OCoLC)1105560517  |z (OCoLC)1235845030 
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060 4 |a 2018 A-989 
060 4 |a QT 37 
072 7 |a HEA  |x 012000  |2 bisacsh 
072 7 |a HEA  |x 020000  |2 bisacsh 
072 7 |a MED  |x 004000  |2 bisacsh 
072 7 |a MED  |x 101000  |2 bisacsh 
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245 0 0 |a Peptides and proteins as biomaterials for tissue regeneration and repair /  |c edited by M�ario A. Barbosa, M. Cristina L. Martins. 
260 |a Duxford :  |b Woodhead Publishing,  |c �2018. 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Woodhead Publishing series in biomaterials 
588 0 |a Print version record. 
504 |a Includes bibliographical references and index. 
505 0 |a Front Cover; Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair; Copyright; Contents; Contributors; Preface; Peptides and proteins as biomaterials for tissue regeneration and repair; Chapter 1: Fundamentals of protein and cell interactions in biomaterials; 1.1 Fundamentals of protein adsorption on biomaterials; 1.1.1 Basics of protein adsorption; 1.1.1.1 Function and structural organization; 1.1.1.2 Structure and orientation of adsorbed proteins; 1.1.2 Interactions with the surface: hydrophobic and electrostatic bonding; 1.1.3 Kinetics of protein adsorption. 
505 8 |a 1.1.4 Conformational changes and stability1.1.5 Reversibility of protein adsorption; 1.1.6 Competitive adsorption behavior; 1.2 Biomaterial surface properties and their effect on protein adsorption; 1.2.1 Promoting protein adsorption: Osseointegration; 1.2.2 Preventing protein adsorption: Hemocompatibility; 1.3 Quantification of protein adsorption; 1.3.1 Optical; 1.3.1.1 Ellipsometry; 1.3.1.2 Surface plasmon resonance; 1.3.2 Spectroscopic; 1.3.2.1 Fluorescent spectroscopy; 1.3.2.2 Infrared absorption spectroscopy; 1.3.3 Microscopic; 1.3.3.1 Atomic force microscopy (AFM); 1.3.4 Radiolabeling. 
505 8 |a 1.3.5 Quartz crystal microbalance with dissipation monitoring (QCM-D)1.4 The importance of adsorbed proteins in the tissue reaction to biomaterials; 1.4.1 Effect of adsorbed proteins on cell adhesion; 1.4.2 Effect of adsorbed proteins on cell activation; 1.4.3 Effect of adsorbed proteins on the FBR; 1.5 Quantification/detection of cell adhesion and activation; 1.5.1 Cell adhesion; 1.5.1.1 Micropatterning; 1.5.1.2 Three-dimensional traction force microscopy (3D-TFM); 1.5.1.3 QCM-D; 1.5.1.4 Microfluidic; 1.5.1.5 AFM; 1.5.2 Cell activation; 1.5.2.1 Fluorescence microscopy; 1.5.2.2 Flow cytometry. 
505 8 |a 1.5.2.3 Enzyme-linked immunosorbent assay (ELISA)1.6 Concluding remarks; References; Chapter 2: Extracellular matrix constitution and function for tissue regeneration and repair; 2.1 An overview of ECM structure and function; 2.1.1 Architectural role; 2.1.2 Adhesion mediator; 2.1.3 Mechanosensor; 2.1.4 Growth factor reservoir and modulator of signaling peptides; 2.2 Major ECM components; 2.2.1 Collagen; 2.2.2 Proteoglycans; 2.2.3 Other ECM molecules; 2.2.4 Matrix-degrading enzymes; 2.3 ECM dynamics in development; 2.3.1 General aspects/processes; 2.3.1.1 Embryogenesis. 
505 8 |a 2.3.1.2 Branching morphogenesis2.3.1.3 Stem cell niches and stem cell differentiation; 2.3.1.4 Homeostasis; 2.3.2 How systems work; 2.3.2.1 ECM in nervous system development; 2.3.2.2 Skeletal development; 2.3.2.3 Skin development; 2.4 ECM remodeling in regeneration and repair; 2.4.1 Intervertebral disc regeneration; 2.4.2 Wound healing; 2.4.3 Bone remodeling and healing; 2.4.4 CNS regeneration and repair; 2.5 Conclusions; References; Chapter 3: Surface functionalization of biomaterials for bone tissue regeneration and repair; 3.1 General introduction and chapter overview. 
650 0 |a Biomedical materials. 
650 0 |a Peptides. 
650 0 |a Proteins. 
650 0 |a Regeneration (Biology) 
650 0 |a Tissue engineering. 
650 1 2 |a Biocompatible Materials  |0 (DNLM)D001672 
650 2 2 |a Peptides  |0 (DNLM)D010455 
650 2 2 |a Proteins  |0 (DNLM)D011506 
650 2 2 |a Tissue Engineering  |0 (DNLM)D023822 
650 2 2 |a Regeneration  |0 (DNLM)D012038 
650 6 |a Biomat�eriaux.  |0 (CaQQLa)201-0025723 
650 6 |a Peptides.  |0 (CaQQLa)201-0006528 
650 6 |a Prot�eines.  |0 (CaQQLa)201-0008150 
650 6 |a R�eg�en�eration (Biologie)  |0 (CaQQLa)201-0015702 
650 6 |a G�enie tissulaire.  |0 (CaQQLa)201-0392445 
650 7 |a protein.  |2 aat  |0 (CStmoGRI)aat300206575 
650 7 |a HEALTH & FITNESS  |x Holism.  |2 bisacsh 
650 7 |a HEALTH & FITNESS  |x Reference.  |2 bisacsh 
650 7 |a MEDICAL  |x Alternative Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Atlases.  |2 bisacsh 
650 7 |a MEDICAL  |x Essays.  |2 bisacsh 
650 7 |a MEDICAL  |x Family & General Practice.  |2 bisacsh 
650 7 |a MEDICAL  |x Holistic Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Osteopathy.  |2 bisacsh 
650 7 |a Tissue engineering  |2 fast  |0 (OCoLC)fst01151484 
650 7 |a Biomedical materials  |2 fast  |0 (OCoLC)fst00832586 
650 7 |a Peptides  |2 fast  |0 (OCoLC)fst01057564 
650 7 |a Proteins  |2 fast  |0 (OCoLC)fst01079711 
650 7 |a Regeneration (Biology)  |2 fast  |0 (OCoLC)fst01093042 
700 1 |a Barbosa, M�ario A. 
700 1 |a Martins, M. Cristina L. 
776 0 8 |i Print version:  |t Peptides and proteins as biomaterials for tissue regeneration and repair.  |d Duxford : Woodhead Publishing, �2018  |z 0081008031  |z 9780081008034  |w (OCoLC)973915065 
830 0 |a Woodhead Publishing series in biomaterials. 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780081008034  |z Texto completo