Water extraction of bioactive compounds : from plants to drug development /

Water Extraction of Bioactive Compounds: From Plants to Drug Development draws together the expert knowledge of researchers from around the world to outline the essential knowledge and techniques required to successfully extract bioactive compounds for further study. The book is a practical tool for...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Dom�inguez, Herminia (Editor ), Gonz�alez Mu�noz, Mar�ia Jes�us (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam, Netherlands ; Cambridge, MA : Elsevier, [2017]
Temas:
Plant bioactive compounds > Separation.
Pharmaceutical technology.
Technology, Pharmaceutical
Compos�es bioactifs v�eg�etaux > S�eparation.
Techniques pharmaceutiques.
MEDICAL > Pharmacology.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Water Extraction of Bioactive Compounds; Water Extraction of Bioactive Compounds; Copyright; Contents; List of Contributors; Foreword; Preface; 1
  • Introduction; 1. BOTANICAL THERAPY; 1.1 Plant Constituents and Biological Actions; 1.2 Strategies in the Discovery of Novel Botanical Bioactives; 1.3 Challenges and Opportunities for Natural Products; 2. SUSTAINABLE SOURCES AND UTILIZATION OF BIOACTIVES; 3. EXTRACTION; 3.1 Mechanisms and Kinetics; 3.2 Mathematical Modeling; 3.2.1 Fick's Law Model; 3.2.2 Empirical Models; 3.3 Operational Variables.
  • 3.3.1 Thermal and Mechanical Treatments3.3.2 Particle Size; 3.3.3 Temperature; 3.3.4 Solvent; 3.3.5 Solvent-to-Solid Ratio; 3.3.6 Searching for Green Solvents; 4. ADVANCED EXTRACTION PROCESSES; 4.1 Nonconventional Green Extraction Techniques; 4.2 Intensified Strategies; 4.3 Intensified Assisted Solvent Extraction Techniques; 4.3.1 Subcritical Water Extraction; 4.3.2 Microwave-Assisted Extraction; 4.3.3 Ultrasonic-Assisted Extraction; 4.3.4 Enzyme-Assisted Extraction; 4.3.5 Electrically Assisted Extraction; 4.3.5.1 High-Voltage Electrical Discharge; 4.3.5.2 Pulsed Electric Field.
  • 4.3.6 Negative Pressure Cavitation Extraction4.3.6.1 Future Trends; REFERENCES; 2
  • Therapeutic Compounds From Plants Using Subcritical Water Technology; 1. INTRODUCTION; 2. PROPERTIES OF WATER; 2.1 The Hydrogen Bond; 2.2 Density and Viscosity; 2.3 The Dielectric Constant; 2.4 Ion Product; 3. INSTRUMENTS AND BASIC EXPERIMENTAL SETUP FOR SWE; 4. APPLICATION OF SWE IN PHARMACEUTICAL INDUSTRY; 4.1 Extraction of Essential Oils; 4.2 Preparation of Plant Extracts; 4.3 Extraction of Phenolic Compounds; 4.4 Preparation of Enriched Extract; 4.5 Extraction of Polysaccharides.
  • 4.6 Extraction of Alkaloids4.7 Extraction of Other Natural Products; REFERENCES; FURTHER READING; 3
  • Hydrolysis of Biopolymers in Near-Critical and Subcritical Water; 1. INTRODUCTION; 2. PROPERTIES OF WATER IN NEAR-CRITICAL AND SUBCRITICAL WATER; 2.1 Ion Product; 2.2 Dielectric Constant; 2.3 Water Density; 2.4 Hydrogen Bonding; 3. PLANT BIOPOLYMERS: CELLULOSE, HEMICELLULOSE, AND LIGNIN; 3.1 Cellulose; 3.2 Hemicellulose; 3.3 Lignin; 4. DEGRADATION PATHWAYS OF PLANT BIOPOLYMERS; 4.1 Cellulose; 4.2 Hemicellulose; 4.3 Lignin; 5. SUBCRITICAL WATER EXTRACTION FOR MACROALGAE; 5.1 Carrageenan.
  • 5.2 Phenolic Compounds6. CONCLUSION AND FUTURE DIRECTION; REFERENCES; 4
  • Subcritical Water Extraction and Neoformation of Antioxidants; 1. INTRODUCTION; 2. FUNDAMENTALS OF SUBCRITICAL WATER EXTRACTION; 2.1 Temperature; 2.2 Pressure; 2.3 Flow Rate and Extraction Time; 2.4 Other Parameters; 3. INSTRUMENTATION FOR SUBCRITICAL WATER EXTRACTION; 4. EXTRACTION OF ANTIOXIDANTS BY SUBCRITICAL WATER EXTRACTION; 5. NEOFORMATION OF ANTIOXIDANTS BY SUBCRITICAL WATER EXTRACTION; 5.1 Formation of Antioxidants Due To Hydrolysis; 5.2 Formation of Antioxidants Due To Degradation Mechanisms.

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