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Environmental factors in neurodegenerative diseases /

Environmental Factors in Neurodegenerative Diseases, Volume One addresses contemporary advances in neurotoxicology, with thematic volumes providing authoritative review articles on key issues in the field. Updates in this new volume include chapters on Air pollution and neurodegenerative diseases, M...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Formato: Electrónico eBook
Idioma:Inglés
Publicado: [Place of publication not identified] : Academic Press, 2017.
Colección:Advances in neurotoxicology ; v. 1.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • 2.3. Exposure Assessment and Studies of Specific Pesticides2.3.1. Rotenone; 2.3.2. Paraquat; 2.3.3. Organochlorine Pesticides; 2.3.4. Specific Organochlorines; 2.3.5. Other Pesticide Associations; 2.4. Studies of Interaction Between Genes and Environment; 3. Experimental Evidence; 3.1. Pesticides and Nigrostriatal Degeneration: Rotenone and Paraquat; 3.1.1. Rotenone; 3.1.2. Paraquat; 3.2. Rotenone, Paraquat, and [alpha]-Synuclein; 3.2.1. [alpha]-Synuclein and Rotenone; 3.2.2. [alpha]-Synuclein and Paraquat; 3.3. Additional Features of PD-Relevant Pesticides
  • Front Cover; Environmental Factors in Neurodegenerative Diseases; Copyright; Contents; Contributors; Preface; Chapter One: Traffic-Related Air Pollution and Neurodegenerative Diseases: Epidemiological and Experimental Evidence, and ... ; 1. Introduction; 2. The CNS as a Target for Air Pollution Toxicity; 2.1. Neurotoxicity in Adults: Epidemiological and Animal Studies; 2.2. Developmental Neurotoxicity; 3. Air Pollution and Neurodegenerative Diseases; 3.1. Air Pollution and PD; 3.2. Air Pollution and Amyotrophic Lateral Sclerosis; 3.3. Air Pollution and Multiple Sclerosis
  • 3.4. Air Pollution and Alzheimer's Disease and Other Dementias4. Possible Mechanisms Linking Air Pollution to Neurodegeneration; 4.1. Adult Neurogenesis; 4.2. MicroRNAs; 4.3. Telomere Length; 4.4. Reelin; 4.5. Glutamate; 5. Conclusion and Research Needs; Acknowledgments; References; Further Reading; Chapter Two: The Catecholaminergic Neurotransmitter System in Methylmercury-Induced Neurotoxicity; 1. Introduction; 2. The Catecholaminergic Neurotransmitter System: General Aspects; 3. Catecholamines in Neurological and Neuropsychiatric Disorders
  • 4. The Catecholaminergic Neurotransmitter System as a Potential Target of Neurotoxicants and Related Consequences5. Methylmercury: General Aspects and Major Mechanisms of Neurotoxicity; 6. Methylmercury-Mediated Catecholaminergic Toxicity; 6.1. Dopamine; 6.2. Epinephrine; 7. Concluding Remarks; Acknowledgments; References; Further Reading; Chapter Three: Pesticides and Parkinson's Disease: Current Experimental and Epidemiological Evidence; 1. Introduction; 2. Epidemiological Evidence; 2.1. Studies of Occupations; 2.2. Studies of Exposure to Pesticides
  • 3.3.1. Long-Lasting Effects and Toxicant Interactions3.3.2. Gender Differences and Genetic Determinants of Pesticide Neurotoxicity; 3.3.3. Pesticide-Induced Transcriptional Alterations; 4. Final Remarks; Acknowledgment; References; Chapter Four: Metals and Circadian Rhythms; 1. Introduction; 2. Manganese; 3. Copper; 4. Zinc; 5. Lead; 6. Mercury; 7. Aluminum; 8. Conclusion; Acknowledgments; References; Chapter Five: Aluminum and Neurodegenerative Diseases; 1. Introduction; 2. Growing Bioavailability of Aluminum in the Environment