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Advances in genetics. Volume 98 /
"Advances in Genetics, Volume 98 provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cambridge, MA :
Academic Press,
2017.
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| Edición: | First edition. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo Texto completo |
Tabla de Contenidos:
- Front Cover; Advances in Genetics; ADVANCES IN GENETICS, VOLUME 98; ADVANCES IN GENETICS; Contents; CONTRIBUTORS; One
- Evolving Centromeres and Kinetochores; 1. INTRODUCTION; 2. CENTROMERES: FROM POINT TO HOLO; 2.1 Fungal Centromeres; 2.1.1 All the Centromere Diversity in One Kingdom; 2.2 Plant Centromeres; 2.2.1 Long and Retro; 2.3 Animal Centromeres; 2.4 Holocentrics; 2.5 Centromere Summary; 3. KINETOCHORE PROTEINS: SIMILAR YET SO DIVERSE; 3.1 CENP-A; 3.1.1 Building the Foundation for the Kinetochore; 3.2 Inner Kinetochore; 3.2.1 The Protein Web of Chromosome Segregation
- 3.3 The Outer Kinetochore3.3.1 The Flexible, Load-Bearing Bridge-to-Spindle Microtubules; 4. FUNGAL OPPORTUNITIES; 5. SUMMARY AND OUTLOOK; ACKNOWLEDGMENTS; REFERENCES; FURTHER READING; Two
- The Genetics of Parkinson Disease; 1. TIMELINE OF PARKINSON DISEASE RESEARCH; 2. ENVIRONMENTAL BASIS OF PARKINSON DISEASE; 3. GENETIC BASIS OF PARKINSON DISEASE; 4. AUTOSOMAL DOMINANT PARKINSON DISEASE; 4.1 Pathogenic Role of SNCA; 4.2 Pathogenic Role of LRRK2; 5. AUTOSOMAL RECESSIVE PARKINSON DISEASE; 5.1 PRKN; 5.2 PINK; 5.3 DJ-1; 6. THE PAST AND THE FUTURE OF PARKINSON DISEASE THERAPIES; 7. CONCLUSIONS
- 5.1.2 Kearns-Sayre Syndrome5.1.3 Chronic Progressive External Ophthalmoplegia; 5.2 Mitochondrial DNA-Encoded Maternally Inherited Diseases; 5.2.1 Leigh Syndrome; 5.2.2 Neuropathy, Ataxia, and Retinitis Pigmentosa; 5.2.3 Leber Hereditary Optic Neuropathy; 5.2.4 Myoclonus, Epilepsy With Ragged Red Fibers; 5.2.5 Mitochondrial Encephalomyopathy, Lactic Acidosis, and Strokelike Episodes; 6. NUCLEAR-ENCODED MITOCHONDRIAL DISORDERS; 6.1 Disorders of Mitochondrial DNA Integrity and Stability; 6.1.1 Mitochondrial DNA Replication Apparatus; 6.1.2 Defects in Deoxyribonucleoside Triphosphates Pool
- 6.1.3 Mitochondrial Network Dynamics6.1.4 Mitochondrial Transcription; 6.1.5 Mitochondrial Protein Synthesis and Maintenance; 6.1.6 Mitochondrial Protein Impart; 6.1.7 Mitochondrial Carrier Transporters; 6.1.8 Unclear Function; 6.2 Defects in mtRNA Translation; 6.2.1 Mitoribosome Assembly; 6.2.2 mt-tRNA Aminoacylation; 6.2.3 mt-tRNA Processing and Modification; 6.2.4 mt-mRNA Processing; 6.2.5 Mitochondrial Translation; 6.3 Defects of the Inner Mitochondrial Membrane Lipid Environment; 6.4 Nuclear-Encoded Mitochondrial Electron Transport Chain Subunits and Assembly/Ancillary Factors