Animal models for the study of human disease /

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Animal Models for the Study of Human Disease, Second Edition, provides needed information on model sharing, animal alternatives, animal ethics and access to databanks of models, bringing together common descriptions of models for busy researchers across biomedical and biological sciences. Offering e...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Conn, P. Michael (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London, United Kingdom : Academic Press is an imprint of Elsevier, 2017.
Edición:Second edition.
Temas:
Diseases > Animal models.
Laboratory animals.
Pathology, Experimental.
Disease Models, Animal
Animals, Laboratory
Maladies > Mod�eles animaux.
Animaux de laboratoire.
Pathologie exp�erimentale.
HEALTH & FITNESS > Diseases > General.
MEDICAL > Clinical Medicine.
MEDICAL > Diseases.
MEDICAL > Evidence-Based Medicine.
MEDICAL > Internal Medicine.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover; Dedication; Title Page; Copyright Page; Dedication; Contents; List of Contributors; Preface; Part A
  • Ethics, resources, and approaches; Chapter 1
  • Ethics in Biomedical Animal Research: The Key Role of the Investigatora; 1
  • Nature and Scope of the Chapter; 2
  • The Subject Matter of Biomedical Animal Research Ethics; 3
  • Why Investigators Should Care About Biomedical Animal Research Ethics; 3.1
  • Investigators are Already Committed to High Ethical Standards; 3.2
  • Ethical Treatment of Animals is Required by Law; 3.2.1
  • General Commitment to Ethical Behavior.
  • 3.2.2
  • Legal Requirements Reflecting General or Specific Ethical Principles3.3
  • Ethical Treatment of Animals Promotes Sound Scientific Results; 3.4
  • Ethical Treatment of Animals is Required by Funding Bodies; 3.5
  • Ethical Treatment of Animals is Required by Peer-Reviewed Journals; 3.5.1
  • The ARRIVE Guidelines; 3.6
  • Ethical Treatment of Animals is Essential for Public Support; 3.7
  • Ethical Treatment of Animals is the Right Thing to Do; 4
  • Aspects of Animal Use and Care Relevant to Biomedical Animal Research Ethics; 5
  • Use of Privately Owned Animals in Biomedical Research.
  • 6
  • The Nature of Basic Animal Research6.1
  • "Basic" Research as the Search for Knowledge for its Own Sake; 6.2
  • "Basic" Research as the Search for Fundamental, Underlying Mechanisms, and Causes; 6.3
  • What Investigators Mean by "Basic" Animal Research; 6.4
  • Recommendations; 7
  • Why Investigators Play the Key Role in Ensuring the Ethical Conduct of Animal Research Projects; 7.1
  • The Nature of Principles of Biomedical Animal Research Ethics; 7.2
  • The Need for Scientific Expertise in Applying General Ethical Principles; 7.3
  • The Investigator as Captain of the Experimental Ship.
  • 7.3.1
  • Primacy of Project Goals7.3.2
  • Design and Implementation of Experimental Procedures; 7.3.3
  • The Importance of Sound Science in Ensuring Ethical Animal Experimentation; 7.4
  • The Role of Review Committees and Government Officials in Assessing the Ethical Appropriateness of Animal Experiments; 7.4.1
  • Ethical Review in the United States; 8
  • Sources of Guidance for Investigators in Conducting Ethical Research; 8.1
  • Scientific Resources; 8.2
  • Ethical and Ethically Relevant Resources; 8.2.1
  • Legally Mandated Ethical Principles.
  • 8.2.2
  • Nongovernmental Documents Adherence to Which is Required by Law8.2.3
  • Publications of Workshops, Study Committees, and Nongovernmental Entities; 8.2.4
  • Ethical Guidelines of Professional Associations; 9
  • Developing Useful Ethical Guidelines; 10
  • Fundamental Principles of biomedical animal Research Ethics; F1
  • The Biomedical Research Principle; F2
  • The Animal Research Principle; F3
  • The Nuremberg Principle; F4
  • The Pain and Distress Minimization Principle; F4.1
  • Ethical Foundations of the Pain and Distress Minimization Principle.
  • F4.2
  • Qualifications to the Pain and Distress Minimization Principle.

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