Molecular approach to cancer management /

Molecular Approach to Cancer Management discusses molecular mechanisms of cancer initiation, growth and secondary spread, emphasizing how this information can be used to devise new modes of treatment of cancer, especially in combatting secondary spread. The book addresses the basic concepts relating...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Sherbet, G. V. (Gajanan V.) (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London ; San Diego, CA : Academic Press, 2017.
Temas:
Cancer > Molecular aspects.
Cancer > Management.
Cancer > Treatment.
Neoplasms > therapy
Molecular Medicine
Cancer > Aspect mol�eculaire.
Cancer > Gestion.
Cancer > Traitement.
HEALTH & FITNESS > Diseases > General.
MEDICAL > Clinical Medicine.
MEDICAL > Diseases.
MEDICAL > Evidence-Based Medicine.
MEDICAL > Internal Medicine.
MEDICAL > Oncology.
Cancer > Molecular aspects
Cancer > Treatment
Electronic books.
Internet Resources.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Modulation of growth factor signalling in targeted therapy
  • The TGF-ss family accessory type III receptor function in cancer progression
  • Insulin-like growth factor signalling as a target to control tumour progression
  • Angiogenisis in neoplasia and anti-angiogenesis strategy in the control of tumour growth and metastasis
  • On the trail of TRAIL (TNF-related apoptosis inducing ligand) in tumour growth and angiogenesis
  • Hedgehog (Hh) signalling in EMT (Epithelial Mesenchyme Transition), CSCs (Cancer Stem Cells) and angiogenesis
  • Hippo signalling in cell proliferation, migration and angiogenesis
  • Notch signalling in carcinogenesis
  • Canonical and non-canonical activation of NF-kB in tumorigenesis
  • Tumour suppression and inhibition of angiogenesis by TXNIP (Thioredoxin Interacting protein)
  • Cyclooxygenase-2 inhibitors suppress EMT, CSCs and angiogenesis
  • Endogenous inhibitors of angiogenesis
  • Stem cells in cancer therapy
  • Inhibitor of DNA-binding proteins in angiogenesis
  • Small molecule inhibitors of angiogenesis and cell proliferation
  • Suramin and polysulphonated napthylureas as angiogenesis inhibitors
  • The anti-cancer potential of flavonoids
  • Selenoproteins in cancer control
  • Control of tumour growth and angiogenesis by thalidomide and its analogues
  • Metaformin and its anti-tumour attributes
  • Statins in cancer biology
  • Are there gains to be made in exploring anthrax lethal toxin (LeTx) as a tumour and an angiogenesis inhibitor?
  • The HMG (High Mobility Group) proteins in cancer progression
  • MTAs in EMT activation and tumour and metastasis promotion
  • S100A4 has potential benefits as a therapeutic target
  • Notable approaches to cancer immunotherapy.

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