Models of seizures and epilepsy /

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Pitk�anen, Asla (Editor ), Buckmaster, Paul S. (Editor ), Galanopoulou, Aristea S., 1965- (Editor ), Mosh�e, Solomon L. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London, United Kingdom : Elsevier : Academic Press, [2017]
Edición:Second edition.
Temas:
Epilepsy.
Spasms.
Epilepsy > Animal models.
Convulsions.
Epilepsy
Seizures
Models, Animal
Spasm
Spasmes.
�Epilepsie.
HEALTH & FITNESS > Diseases > General.
MEDICAL > Clinical Medicine.
MEDICAL > Diseases.
MEDICAL > Evidence-Based Medicine.
MEDICAL > Internal Medicine.
Convulsions
Epilepsy > Animal models
Spasms
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover; Title page; Copyright page; Contents; Contributors; Foreword; References; Preface; Part I
  • Introduction; Chapter 1
  • What Can We Model?; Animal models of seizures; Animal models of epilepsy; A way forward; References; Chapter 2
  • Comparative Biology and Species Effects on Expression of Epilepsy; Introduction; How does epilepsy vary across species?; Conservative brain evolution; Vertebrate Phylogeny; Similarities Across Vertebrate Brains; Brain size; Brain Size Affects Circuitry; Mechanisms of brain evolution; Invasion; Loss of Connections; Parcellation; Ontogenetic Buffers
  • Axon DisplacementConcerted and Mosaic Brain Evolution; Tool for Comparing Developmental Stages Across Species; Evolution of the neocortex and hippocampus; Eversion of the Teleost Telencephalon; Amphibian Dorsal Pallium; Reptilian Dorsal Pallium; Dorsal Ventricular Ridge of Reptiles and Birds; Mammalian Neocortex; Pyramidal Cell Evolution; Neocortical Areas; Thalamus; Hippocampal Evolution; Epilepsy-Relevant Species-Specific Hippocampal Characteristics; Conclusions; Acknowledgments; References; Chapter 3
  • Strain Effects on Expression of Seizures and Epilepsy; Introduction
  • Mouse strain effects on expression of seizures and epilepsyMouse Models of Acute Seizures and Seizure Susceptibility; Physically-Induced Seizures; Chemically-Induced Seizures; Antiseizure Drugs; The 6-Hz Psychomotor Seizure Model of Partial Epilepsy in Mice; Mouse Strain Differences in Occurrence of Spike-Wave Discharges; The Pilocarpine Model of Temporal Lobe Epilepsy in Mice; The Kainate Model of Temporal Lobe Epilepsy in Mice; The Intrahippocampal Kainate Model of Temporal Lobe Epilepsy in Mice; The Electrical Kindling Model of Temporal Lobe Epilepsy in Mice
  • The Flurothyl Kindling Mouse Model of Primary Generalized EpilepsiesThe Theiler's Virus Mouse Model of Encephalitis-Induced Temporal Lobe Epilepsy; Rat strain effects on expression of seizures and epilepsy; The Pilocarpine Model of Temporal Lobe Epilepsy in Rats; The Electrical Kindling Model of Temporal Lobe Epilepsy in Rats; Sustained Stimulation of the Basolateral Amygdala in Rats as a Model of Temporal Lobe Epilepsy; Rat Strain Differences in Occurrence of Spike-Wave Discharges or Other EEG Alterations
  • Dissection of genes that may underlie differences in expression of seizures or epilepsySignal-Recognition-Particle Assembly 9 (Srp9); Potassium Voltage-Gated Channel Subfamily J Member 10 (Kcnj10); Multiple PDZ Domain Crumbs Cell Polarity Complex Component (Mpdz); Cholinergic Receptor Genes; Conclusions; Acknowledgments; References; Further Reading; Chapter 4
  • Good Welfare Practice in Modeling Seizures and Epilepsy; General description; Background; Ethics and animal research; Legal Framework; NC3Rs report on welfare in rodent epilepsy models; Intrinsic features of epilepsy models; Seizures

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