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170623s2017 enk ob 001 0 eng d |
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|a Models of seizures and epilepsy /
|c Asla Pitk�anen, Paul S. Buckmaster, Aristea S. Galanopoulou, Solomon L. Mosh�e.
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| 250 |
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|a Second edition.
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| 264 |
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1 |
|a London, United Kingdom :
|b Elsevier :
|b Academic Press,
|c [2017]
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| 300 |
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|a 1 online resource (xxvi, 1151 pages)
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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0 |
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|a Vendor-supplied metadata.
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| 504 |
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|a Includes bibliographical references and index.
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0 |
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|a Cover; Title page; Copyright page; Contents; Contributors; Foreword; References; Preface; Part I -- Introduction; Chapter 1 -- What Can We Model?; Animal models of seizures; Animal models of epilepsy; A way forward; References; Chapter 2 -- Comparative Biology and Species Effects on Expression of Epilepsy; Introduction; How does epilepsy vary across species?; Conservative brain evolution; Vertebrate Phylogeny; Similarities Across Vertebrate Brains; Brain size; Brain Size Affects Circuitry; Mechanisms of brain evolution; Invasion; Loss of Connections; Parcellation; Ontogenetic Buffers
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8 |
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|a Axon DisplacementConcerted and Mosaic Brain Evolution; Tool for Comparing Developmental Stages Across Species; Evolution of the neocortex and hippocampus; Eversion of the Teleost Telencephalon; Amphibian Dorsal Pallium; Reptilian Dorsal Pallium; Dorsal Ventricular Ridge of Reptiles and Birds; Mammalian Neocortex; Pyramidal Cell Evolution; Neocortical Areas; Thalamus; Hippocampal Evolution; Epilepsy-Relevant Species-Specific Hippocampal Characteristics; Conclusions; Acknowledgments; References; Chapter 3 -- Strain Effects on Expression of Seizures and Epilepsy; Introduction
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| 505 |
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|a Mouse strain effects on expression of seizures and epilepsyMouse Models of Acute Seizures and Seizure Susceptibility; Physically-Induced Seizures; Chemically-Induced Seizures; Antiseizure Drugs; The 6-Hz Psychomotor Seizure Model of Partial Epilepsy in Mice; Mouse Strain Differences in Occurrence of Spike-Wave Discharges; The Pilocarpine Model of Temporal Lobe Epilepsy in Mice; The Kainate Model of Temporal Lobe Epilepsy in Mice; The Intrahippocampal Kainate Model of Temporal Lobe Epilepsy in Mice; The Electrical Kindling Model of Temporal Lobe Epilepsy in Mice
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| 505 |
8 |
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|a The Flurothyl Kindling Mouse Model of Primary Generalized EpilepsiesThe Theiler's Virus Mouse Model of Encephalitis-Induced Temporal Lobe Epilepsy; Rat strain effects on expression of seizures and epilepsy; The Pilocarpine Model of Temporal Lobe Epilepsy in Rats; The Electrical Kindling Model of Temporal Lobe Epilepsy in Rats; Sustained Stimulation of the Basolateral Amygdala in Rats as a Model of Temporal Lobe Epilepsy; Rat Strain Differences in Occurrence of Spike-Wave Discharges or Other EEG Alterations
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| 505 |
8 |
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|a Dissection of genes that may underlie differences in expression of seizures or epilepsySignal-Recognition-Particle Assembly 9 (Srp9); Potassium Voltage-Gated Channel Subfamily J Member 10 (Kcnj10); Multiple PDZ Domain Crumbs Cell Polarity Complex Component (Mpdz); Cholinergic Receptor Genes; Conclusions; Acknowledgments; References; Further Reading; Chapter 4 -- Good Welfare Practice in Modeling Seizures and Epilepsy; General description; Background; Ethics and animal research; Legal Framework; NC3Rs report on welfare in rodent epilepsy models; Intrinsic features of epilepsy models; Seizures
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| 650 |
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0 |
|a Epilepsy.
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| 650 |
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0 |
|a Spasms.
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| 650 |
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0 |
|a Epilepsy
|x Animal models.
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| 650 |
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0 |
|a Convulsions.
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| 650 |
1 |
2 |
|a Epilepsy
|0 (DNLM)D004827
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| 650 |
2 |
2 |
|a Seizures
|0 (DNLM)D012640
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| 650 |
2 |
2 |
|a Models, Animal
|0 (DNLM)D023421
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| 650 |
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2 |
|a Spasm
|0 (DNLM)D013035
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| 650 |
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6 |
|a Spasmes.
|0 (CaQQLa)201-0025795
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| 650 |
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6 |
|a �Epilepsie.
|0 (CaQQLa)201-0050894
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| 650 |
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6 |
|a Convulsions.
|0 (CaQQLa)201-0020081
|
| 650 |
|
7 |
|a HEALTH & FITNESS
|x Diseases
|x General.
|2 bisacsh
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| 650 |
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7 |
|a MEDICAL
|x Clinical Medicine.
|2 bisacsh
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| 650 |
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|a MEDICAL
|x Diseases.
|2 bisacsh
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| 650 |
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|a MEDICAL
|x Evidence-Based Medicine.
|2 bisacsh
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| 650 |
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7 |
|a MEDICAL
|x Internal Medicine.
|2 bisacsh
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| 650 |
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7 |
|a Convulsions
|2 fast
|0 (OCoLC)fst00877316
|
| 650 |
|
7 |
|a Epilepsy
|2 fast
|0 (OCoLC)fst00914183
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| 650 |
|
7 |
|a Epilepsy
|x Animal models
|2 fast
|0 (OCoLC)fst00914185
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| 650 |
|
7 |
|a Spasms
|2 fast
|0 (OCoLC)fst01128762
|
| 700 |
1 |
|
|a Pitk�anen, Asla,
|e editor.
|
| 700 |
1 |
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|a Buckmaster, Paul S.,
|e editor.
|
| 700 |
1 |
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|a Galanopoulou, Aristea S.,
|d 1965-
|e editor.
|
| 700 |
1 |
|
|a Mosh�e, Solomon L.,
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|t Models of seizures and epilepsy.
|b Second edition.
|d London, United Kingdom : Elsevier : Academic Press, [2017]
|z 0128040661
|z 9780128040669
|w (OCoLC)965353713
|
| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128040669
|z Texto completo
|
