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Neutron scattering : applications in biology, chemistry, and materials science /
"Neutron Scattering: Applications in Chemistry, Materials Science and Biology, Volume 49, provides an in-depth overview of the applications of neutron scattering in the fields of physics, materials science, chemistry, biology, the earth sciences, and engineering. The book describes the tremendo...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cambridge, MA :
Academic Press is an imprint of Elsevier,
2017.
|
| Colección: | Experimental methods in the physical sciences ;
v. 49. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Neutron Scattering
- Applications in Biology, Chemistry, and Materials Science; Copyright; Contents; List of Contributors; Volumes in Series; Preface; References; Symbols; References; Chapter 1: Biological Structures; 1.1. Introduction: Neutrons and Biological Structures; 1.2. Diffraction; 1.2.1. Macromolecular Crystallography; 1.2.1.1. Instruments; 1.2.1.2. Sample Considerations for Neutron Protein Crystallography; 1.2.2. Neutron Fiber Diffraction; 1.3. Small-Angle Neutron Scattering (SANS); 1.3.1. SANS Instrumentation; 1.3.1.1. Currently Available Instruments
- 1.3.1.2. Future Instruments1.3.2. Sample Preparation; 1.3.3. Data Processing and Analysis; 1.3.3.1. Model Independent Data Analysis; 1.3.3.2. Geometric Modeling; 1.3.3.3. Shape Reconstruction; 1.3.3.4. Molecular Dynamics Simulations and Conformational Searches; 1.4. Neutron Reflectometry; 1.4.1. Specular and Off-Specular Reflection; 1.4.2. Grazing-Incidence SANS (GISANS); 1.4.3. Instruments; 1.4.4. Experimental Considerations; 1.4.4.1. Resolution; 1.4.4.2. Sample Preparation and Sample Environments; 1.4.4.3. Contrast Variation; 1.4.5. Data Analysis and Refinement; 1.5. Membrane Diffraction
- 1.5.1. Instruments, Data Collection, and Analysis1.5.2. Experimental Considerations; 1.6. Deuterium Labeling for Biological Structure Determination; 1.6.1. Protein Deuteration; 1.6.2. Biopolymer Deuteration; 1.6.3. Biomembrane and Small Molecule Deuteration; 1.6.4. Current and Future Deuteration Facilities; 1.6.4.1. D-Lab, ILL-EMBL, Grenoble (France); 1.6.4.2. Biodeuteration Lab (BDL), Oak Ridge National Laboratory, Oak Ridge TN (USA); 1.6.4.3. National Deuteration Facility, ANSTO, Sydney (Australia); 1.6.4.4. STFC Deuteration Facility, ISIS Neutron and Muon Facility, UK
- 1.6.4.5. Deuteration and Macromolecular Crystallization Platform, ESS, Lund (Sweden)1.7. Scientific Highlights; 1.7.1. Neutron Protein Crystallography; 1.7.1.1. Ultra-High Resolution Neutron Studies of Crambin; 1.7.1.2. Dynamic and Static Structural Studies of Amino Acid Protonation; 1.7.1.3. Neutron Studies for Drug Design: HIV Protease in Complex With Amprenavir; 1.7.1.4. Neutron Studies of an Engineered Photo-Switching Chromoprotein, Dathail; 1.7.1.5. Cytochrome c Peroxidase; 1.7.1.6. Urate Oxidase; 1.7.2. Fibre Biomaterials and Structural Biopolymers; 1.7.3. Protein Solution Structures
- 1.7.4. Membrane Structures and Proteins in Membranes1.7.5. Biomedical Applications and Biomaterials; 1.8. Future Perspectives; References; Chapter 2: Dynamics of Biological Systems; 2.1. Introduction; 2.2. Fundamental Aspects and Overview; 2.2.1. Neutron Spectroscopy Fundamentals to Study Biological Systems; 2.2.2. Disambiguation of Symbols; 2.2.3. Collective and Self-Correlation Functions; 2.2.4. Observable Quantities; 2.2.5. Past and Present Topics in the Dynamics of Biological Systems; 2.3. Concepts of Diffusion; 2.3.1. Diffusion Fundamentals; 2.3.2. Diffusion in Colloidal Suspensions