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|a Ion channels DownUnder /
|c edited by Dominic P. Geraghty and Lachlan D. Rash.
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| 246 |
3 |
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|a Ion channels Down Under
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| 264 |
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1 |
|a Cambridge, MA :
|b Academic Press is an imprint of Elsevier,
|c 2017.
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| 300 |
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|a 1 online resource
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| 336 |
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|a text
|b txt
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|a online resource
|b cr
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|a Advances in pharmacology ;
|v volume 79
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| 588 |
0 |
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|a Online resource; title from title details screen (SpringerLink, viewed May 24, 2017).
|
| 505 |
0 |
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|t Preface /
|r Dominic P. Geraghty, Lachlan D. Rash --
|t GABAA receptors and the diversity in their structure and pharmacology /
|r Han Chow Chua, Mary Chebib --
|t Acid-sensing ion channel pharmacology, past, present, and future ... /
|r Lachlan D. Rash --
|t Sodium channels and venom peptide pharmacology /
|r Mathilde R. Israel, Bryan Tay, Jennifer R. Deuis, Irina Vetter --
|t Role of nonneuronal TRPV4 signaling in inflammatory processes /
|r Pradeep Rajasekhar, Daniel P. Poole, Nicholas A. Veldhuis --
|t Genetically encoded calcium indicators as probes to assess the role of calcium channels in disease and for high-throughput drug discovery /
|r John J. Bassett, Gregory R. Monteith --
|t TRPV1 channels in immune cells and hematological malignancies /
|r Sofia A. Omari, Murray J. Adams, Dominic P. Geraghty --
|t Modulation of ion channels by cysteine-rich peptides : from sequence to structure /
|r Mehdi Mobli, Eivind A.B. Undheim, Lachlan D. Rash --
|t Glycine receptor drug discovery /
|r Joseph W. Lynch, Yan Zhang, Sahil Talwar, Argel Estrada-Mondragon --
|t Voltage-gated sodium channel pharmacology : insights from molecular dynamics simulations /
|r Rong Chen, Amanda Buyan, Ben Corry --
|t Physiology and pharmacology of ryanodine receptor calcium release channels /
|r Angela F. Dulhunty, Philip G. Board, Nicole A. Beard, Marco G. Casarotto.
|
| 504 |
|
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|a Includes bibliographical references.
|
| 506 |
|
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|a Owing to Legal Deposit regulations this resource may only be accessed from within National Library of Scotland. For more information contact enquiries@nls.uk.
|5 StEdNL
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| 650 |
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0 |
|a Ion channels.
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| 650 |
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2 |
|a Ion Channels
|0 (DNLM)D007473
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6 |
|a Canaux ioniques.
|0 (CaQQLa)201-0145111
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|a SCIENCE
|x Life Sciences
|x Anatomy & Physiology.
|2 bisacsh
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|
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|a Ion channels
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|0 (OCoLC)fst00978573
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| 700 |
1 |
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|a Geraghty, D. M.
|q (Dominic M.),
|e editor.
|
| 700 |
1 |
|
|a Rash, Lachlan D.,
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|t Ion channels DownUnder
|z 0128104139
|z 9780128104132
|w (DLC) 2017302023
|w (OCoLC)992689577
|
| 830 |
|
0 |
|a Advances in pharmacology (San Diego, Calif.) ;
|v 79.
|
| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/bookseries/10543589/79
|z Texto completo
|
| 880 |
8 |
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|6 505-00/(S
|a 6.2.1. High-Affinity Site: Extracellular α + γ- Interface6.2.2. Low-Affinity Benzodiazepine Binding Site(s); 6.3. Anesthetic Binding Sites in the TMD; 6.3.1. Transmembrane β + α- Interfaces; 6.3.2. Transmembrane α + β- and γ + β- Interfaces; 6.3.3. Transmembrane β + β- Interface; 6.3.4. The Promiscuity of Anesthetics Binding; 6.4. Neurosteroid Binding Sites in the TMD; 6.5. Variable Pharmacology of δ-Containing GABAARs; 6.6. Natural Products of Plant Origin; 7. Conclusion; Conflict of Interest; Acknowledgments; References
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| 880 |
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|6 505-00/(S
|a 1.4.3. NaV1.31.4.4. NaV1.4; 1.4.5. NaV1.5; 1.4.6. NaV1.6; 1.4.7. NaV1.7; 1.4.8. NaV1.8; 1.4.9. NaV1.9; 1.5. Pharmacology of Venom Peptides Acting at NaV Channels; 1.5.1. Pore Blockers; 1.5.1.1. Guanidinium Neurotoxins; 1.5.1.2. μ-Conotoxins; 1.5.2. Gating Modifiers; 1.5.2.1. α-Scorpion Toxins; 1.5.2.2. β-Scorpion Toxins; 1.5.2.3. Sea Anemone Toxins; 1.5.2.4. μ/β-Spider Toxins; 1.5.2.5. μO-Conotoxins; 1.5.2.6. μO GVIIJ; 1.5.2.7. ι-Conotoxins; 1.5.2.8. δ-Conotoxins and δ-Toxins From Spider Venom; 1.5.2.9. Snake Toxins; 2. Conclusion
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|6 505-00/(S
|a Front Cover; Ion Channels DownUnder; Copyright; Contents; Contributors; Preface; Chapter One: GABAA Receptors and the Diversity in their Structure and Pharmacology; 1. Introduction; 2. Architecture of GABAARs; 3. GABAAR Assembly: Selective Subunit Oligomerization; 4. Multiple Subtypes, Locations, and Actions of GABAARs; 5. Subunit Stoichiometry and Arrangement of GABAARs; 6. Pharmacology of GABAARs; 6.1. Orthosteric GABA Binding Sites; 6.1.1. Extracellular β + α- Interfaces; 6.1.2. Alternative GABA-Binding Interfaces; 6.2. Benzodiazepine Binding Sites
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