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The end of Alzheimer's : the brain and beyond /
The End of Alzheimer's: The Brain and Beyond, Second Edition is the first comprehensive overview on the molecular basis of Alzheimer's outside of the brain, merging the most recent findings within the field into a single book. It aims to educate the reader on the many overlooked aspects of...
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Academic Press, an imprint of Elsevier,
�2017.
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| Edición: | Second edition. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Cover; Title page; Copyright page; Dedication; Contents; About the Authors; Foreword; By Jack C. de la Torre, MD, PhD; By Kimer S. McCully, MD; Preface; By Dr. Lewis; By Dr. Trempe; Chapter 1
- Is it Alzheimer's Disease?; Neurodegenerative Diseases and Dementia; True Dementias; Alzheimer's Disease; Alzheimer's Versus Dementias; Multifactorial Alzheimer's; What if Alzheimer's Is Not Isolated to the Brain?; Differential Diagnosis; Beta-Amyloid and Alzheimer's; Diseases That Occur With Alzheimer's; Impact of Alzheimer's; Treatable Dementias and "Senior Moments"; Head Injury; Acute Infections.
- Normal Pressure HydrocephalusSimple Hydrocephalus; Brain Tumors; Toxic Exposure; Metabolic Disorders; Hormone Disorders; Poor Oxygenation (Hypoxia); Blood Pressure; Drug Reactions, Overuse, or Abuse; Nutritional Issues; Sodium Deficiency; Chronic Alcoholism; Other Neurodegenerative Disorders; Vascular Dementia; Parkinson's Disease; Lewy Body Dementia; Huntington's Disease; Creutzfeldt-Jakob Disease; Pick's Disease (Frontotemporal Dementia); Conclusions; References; Chapter 2
- The Amyloid Cascade Hypothesis; Evidence Against the Amyloid Cascade Hypothesis.
- Research Opposed to the Amyloid Cascade HypothesisDrug Companies Committed to the Amyloid Hypothesis; Eli Lilly; Johnson & Johnson and Pfizer; Bristol-Myers Squibb; Pfizer and Medivation; Merck; The Animal Model for Alzheimer's and Beta-Amyloid Therapy; If Not Amyloid, What Next?; What Use Does Amyloid Serve? Diagnostics; Tau-Neurofibrillary Tangles: The "Other" Hallmark; Proposed Tau Therapies; Hyperphosphorylated Tau Occurs Naturally in Healthy Animals; References; Chapter 3
- Diagnosis of Alzheimer's-Standard-of-Care; Alzheimer's Diagnosis: Standard-of-Care; Mental Status Tests.
- Mini-Mental State ExaminationMini-Cog; Mood Assessment; Brain Imaging; Objective Evaluation: Standard-of-Care; The First Alzheimer's Diagnosis; Standard-of-Care Diagnosis at Autopsy; Cognitive Tests and Human Memory; Cognitive Functioning Tests Explored; The Mini-Mental State Examination; Neurological Tests Beyond the MMSE; Limits of Cognitive Tests; Advanced Diagnosis Within the Standard-of-Care; Advanced Brain Imaging; Magnetic Resonance Imaging; Positron Emission Tomography; X-Ray Computer Tomography Scan; Who Creates Diagnostic Criteria?; References; Chapter 4
- Diagnostic Accuracy.
- Diagnosis ExploredMisdiagnosis; Prevalence of Misdiagnosis; Why Does Misdiagnosis Occur?; Patient; Doctor; Doctors Are Not the Problem; Causes of Misdiagnosis; Preventing Misdiagnosis; A 300-Billion Diagnostic Error; Baseline Disease 1-Pellagra; Baseline Disease 2-Tuberculosis; Baseline Disease 3-Typhoid Fever; Statins and Cardiovascular Disease; Statins Trigger Memory Problems; Link Between Low Cholesterol and Mortality; Cholesterol and Alzheimer's Disease; Misdiagnosis: Case Study; References; Chapter 5
- Can Medicine Save You?; Do We Need Drugs to Be Healthy?