Cargando…

The end of Alzheimer's : the brain and beyond /

The End of Alzheimer's: The Brain and Beyond, Second Edition is the first comprehensive overview on the molecular basis of Alzheimer's outside of the brain, merging the most recent findings within the field into a single book. It aims to educate the reader on the many overlooked aspects of...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Lewis, Thomas J., 1959- (Autor)
Otros Autores: Trempe, Clement L.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, an imprint of Elsevier, �2017.
Edición:Second edition.
Temas:
Acceso en línea:Texto completo

MARC

LEADER 00000cam a2200000Ia 4500
001 SCIDIR_ocn987725951
003 OCoLC
005 20231120112231.0
006 m o d
007 cr cnu|||unuuu
008 170520s2017 enka ob 001 0 eng d
010 |a  2017302046 
040 |a EBLCP  |b eng  |e pn  |c EBLCP  |d YDX  |d N$T  |d IDEBK  |d OCLCF  |d OCLCQ  |d TEFOD  |d OPELS  |d TKN  |d MERER  |d OCLCQ  |d UPM  |d CASUM  |d OCLCQ  |d OCLCO  |d OCLCQ  |d OCLCA  |d USU  |d D6H  |d OCLCO  |d DKU  |d OCLCO  |d U3W  |d KSU  |d RRP  |d OCLCO  |d OCLCQ  |d AU@  |d OCLCO  |d OCLCQ  |d WYU  |d OCLCO  |d OCLCQ  |d LQU  |d UKAHL  |d OCLCQ  |d OCLCO  |d S2H  |d OCLCO  |d VT2  |d OCLCO  |d OCLCQ  |d SFB  |d OCLCO 
016 7 |a 101713164  |2 DNLM 
019 |a 987345943  |a 987432825  |a 1066464156  |a 1105191945  |a 1105564809  |a 1235834030 
020 |a 9780128121139  |q (electronic bk.) 
020 |a 0128121130  |q (electronic bk.) 
020 |z 0128121122 
020 |z 9780128121122 
035 |a (OCoLC)987725951  |z (OCoLC)987345943  |z (OCoLC)987432825  |z (OCoLC)1066464156  |z (OCoLC)1105191945  |z (OCoLC)1105564809  |z (OCoLC)1235834030 
050 4 |a RC523 
060 4 |a 2017 G-989 
060 4 |a WT 155 
072 7 |a MED  |x 033000  |2 bisacsh 
082 0 4 |a 618.97683  |2 23 
100 1 |a Lewis, Thomas J.,  |d 1959-  |e author. 
245 1 4 |a The end of Alzheimer's :  |b the brain and beyond /  |c Thomas J. Lewis nand Clement L. Trempe. 
250 |a Second edition. 
260 |a London :  |b Academic Press, an imprint of Elsevier,  |c �2017. 
300 |a 1 online resource (484 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record. 
505 0 |a Cover; Title page; Copyright page; Dedication; Contents; About the Authors; Foreword; By Jack C. de la Torre, MD, PhD; By Kimer S. McCully, MD; Preface; By Dr. Lewis; By Dr. Trempe; Chapter 1 -- Is it Alzheimer's Disease?; Neurodegenerative Diseases and Dementia; True Dementias; Alzheimer's Disease; Alzheimer's Versus Dementias; Multifactorial Alzheimer's; What if Alzheimer's Is Not Isolated to the Brain?; Differential Diagnosis; Beta-Amyloid and Alzheimer's; Diseases That Occur With Alzheimer's; Impact of Alzheimer's; Treatable Dementias and "Senior Moments"; Head Injury; Acute Infections. 
505 8 |a Normal Pressure HydrocephalusSimple Hydrocephalus; Brain Tumors; Toxic Exposure; Metabolic Disorders; Hormone Disorders; Poor Oxygenation (Hypoxia); Blood Pressure; Drug Reactions, Overuse, or Abuse; Nutritional Issues; Sodium Deficiency; Chronic Alcoholism; Other Neurodegenerative Disorders; Vascular Dementia; Parkinson's Disease; Lewy Body Dementia; Huntington's Disease; Creutzfeldt-Jakob Disease; Pick's Disease (Frontotemporal Dementia); Conclusions; References; Chapter 2 -- The Amyloid Cascade Hypothesis; Evidence Against the Amyloid Cascade Hypothesis. 
505 8 |a Research Opposed to the Amyloid Cascade HypothesisDrug Companies Committed to the Amyloid Hypothesis; Eli Lilly; Johnson & Johnson and Pfizer; Bristol-Myers Squibb; Pfizer and Medivation; Merck; The Animal Model for Alzheimer's and Beta-Amyloid Therapy; If Not Amyloid, What Next?; What Use Does Amyloid Serve? Diagnostics; Tau-Neurofibrillary Tangles: The "Other" Hallmark; Proposed Tau Therapies; Hyperphosphorylated Tau Occurs Naturally in Healthy Animals; References; Chapter 3 -- Diagnosis of Alzheimer's-Standard-of-Care; Alzheimer's Diagnosis: Standard-of-Care; Mental Status Tests. 
505 8 |a Mini-Mental State ExaminationMini-Cog; Mood Assessment; Brain Imaging; Objective Evaluation: Standard-of-Care; The First Alzheimer's Diagnosis; Standard-of-Care Diagnosis at Autopsy; Cognitive Tests and Human Memory; Cognitive Functioning Tests Explored; The Mini-Mental State Examination; Neurological Tests Beyond the MMSE; Limits of Cognitive Tests; Advanced Diagnosis Within the Standard-of-Care; Advanced Brain Imaging; Magnetic Resonance Imaging; Positron Emission Tomography; X-Ray Computer Tomography Scan; Who Creates Diagnostic Criteria?; References; Chapter 4 -- Diagnostic Accuracy. 
505 8 |a Diagnosis ExploredMisdiagnosis; Prevalence of Misdiagnosis; Why Does Misdiagnosis Occur?; Patient; Doctor; Doctors Are Not the Problem; Causes of Misdiagnosis; Preventing Misdiagnosis; A 300-Billion Diagnostic Error; Baseline Disease 1-Pellagra; Baseline Disease 2-Tuberculosis; Baseline Disease 3-Typhoid Fever; Statins and Cardiovascular Disease; Statins Trigger Memory Problems; Link Between Low Cholesterol and Mortality; Cholesterol and Alzheimer's Disease; Misdiagnosis: Case Study; References; Chapter 5 -- Can Medicine Save You?; Do We Need Drugs to Be Healthy? 
500 |a The Commercialization of Health Care. 
520 |a The End of Alzheimer's: The Brain and Beyond, Second Edition is the first comprehensive overview on the molecular basis of Alzheimer's outside of the brain, merging the most recent findings within the field into a single book. It aims to educate the reader on the many overlooked aspects of Alzheimer's disease that occur outside the brain. This book uniquely provides step-by-step, peer-reviewed evidence that the current research model may be misguided and that a new and emerging model is more accurate. It carefully outlines the molecular research in Alzheimer's outside the brain and argues that a more thorough, whole-body diagnosis will provide better answers about its causes and lead to new treatments. It is beneficial to researchers who need to be apprised of the emerging science on the causes of Alzheimer's, and will hopefully redirect many into new avenues of cellular research and discovery. 
650 0 |a Alzheimer's disease. 
650 1 2 |a Alzheimer Disease  |0 (DNLM)D000544 
650 6 |a Maladie d'Alzheimer.  |0 (CaQQLa)201-0114128 
650 7 |a MEDICAL  |x Gynecology & Obstetrics.  |2 bisacsh 
650 7 |a Alzheimer's disease  |2 fast  |0 (OCoLC)fst00806532 
655 0 |a Electronic books. 
655 4 |a Internet Resources. 
700 1 |a Trempe, Clement L. 
776 0 8 |i Print version:  |a Lewis, Thomas J.  |t End of Alzheimer's : The Brain and Beyond.  |d Saint Louis : Elsevier Science, �2017  |z 9780128121122 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780128121122  |z Texto completo