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Reproductive and developmental toxicology /

Of the Effects of Estrogens and Progesterone During the Female Reproductive Cycle -- Oocyte/Sperm Transport, Normal Capacitation of Sperm, and Fertilization -- Transport of the Ovulated Oocyte -- Transport and Capacitation of Spermatozoa -- Transport of Spermatozoa -- Capacitation of Spermatozoa --...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Gupta, Ramesh C. (Ramesh Chandra), 1949- (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Saint Louis : Elsevier Science, 2017.
Edición:Second edition.
Temas:
Acceso en línea:Texto completo

MARC

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072 7 |a MED  |x 096000  |2 bisacsh 
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082 0 4 |a 616.6/5071 
245 0 0 |a Reproductive and developmental toxicology /  |c edited by Ramesh C. Gupta. 
250 |a Second edition. 
264 1 |a Saint Louis :  |b Elsevier Science,  |c 2017. 
300 |a 1 online resource (xiii, 1446 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record. 
505 0 |a Front Cover; REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY; REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY; Copyright; Contents; List of Contributors; I -- GENERAL; 1 -- Introduction; Reference; 2 -- Reproductive Anatomy and Physiology; INTRODUCTION; IMPORTANT DEFINITIONS AND CONCEPTS; Reproduction; Hormones and Hormone Receptors; Gonadal Steroid Hormones and Their "Nuclear" Receptors; Genomic and Nongenomic Mechanisms of Action of Gonadal Steroid Hormones; REVIEW OF NORMAL HUMAN REPRODUCTION; Historical Perspectives and Complexity of Reproductive Function. 
505 8 |a Relevance of a Basic Understanding of Human Reproductive Anatomy and PhysiologyNeuroendocrine Control of Reproduction; Puberty and Sexual Maturity; The Onset of Puberty; The Endocrinology of Puberty; Normal Male Reproductive Anatomy and Physiology; Developmental Perspectives; Reproductive Anatomy of the Male; Testicular Structure; Excurrent Duct System; Accessory Sex Glands; External Genitalia; Spermatogenesis; Proliferation (Mitosis or Spermatocytogenesis); Meiosis; Differentiation (Spermiogenesis); The Cycle of the Seminiferous Epithelium; Male Reproductive Physiology. 
505 8 |a Gonadal Steroid Synthesis in the TestesEndocrine Regulation of Spermatogenesis; Positive and Negative Feedback Loops Involved in Male Reproduction; Epididymal and Accessory Sex Gland Function; Sexual Behavior, Erection, Emission, and Ejaculation; Normal Female Reproductive Anatomy and Physiology; Developmental Perspectives; Reproductive Anatomy of the Female; Female Reproductive Physiology; The Estrous Cycle; The Menstrual Cycle; Follicular Development; Ovarian Follicular Synthesis of Estrogens; The Effects of Estrogenic Feedback on the Hypothalamic-Pituitary-Gonadal Axis; Ovulation. 
505 8 |a Formation and Function of a Corpus LuteumSummary of the Effects of Estrogens and Progesterone During the Female Reproductive Cycle; Oocyte/Sperm Transport, Normal Capacitation of Sperm, and Fertilization; Transport of the Ovulated Oocyte; Transport and Capacitation of Spermatozoa; Transport of Spermatozoa; Capacitation of Spermatozoa; Fertilization; Important Aspects of Normal Embryonic and Fetal Development; Historical Perspective; Blastocyst Formation and Differentiation of the Germ Cell Layers; "Maternal Recognition of Pregnancy" and Implantation; Formation of the Extraembryonic Membranes. 
505 8 |a Concepts and DefinitionsPlacental Types; Placental Function; The "Placental Barrier"; Sex Determination and Sexual Differentiation of Reproductive Function; Genotypic Sex and Development of the Primitive Sex Cords; Gonadal Sex Determination and Phenotypic Sexual Differentiation; Development of the Male Phenotype; Development of the Female Phenotype; Sexual Differentiation of the Brain; The Endocrinology of Pregnancy; Gestational Hormones; Parturition; Physiology of Parturition; The Mammary Glands; Anatomy; Physiology of Lactation; Lactogenesis; Control of Prolactin Secretion. 
500 |a Reproductive Senescence. 
520 |a Of the Effects of Estrogens and Progesterone During the Female Reproductive Cycle -- Oocyte/Sperm Transport, Normal Capacitation of Sperm, and Fertilization -- Transport of the Ovulated Oocyte -- Transport and Capacitation of Spermatozoa -- Transport of Spermatozoa -- Capacitation of Spermatozoa -- Fertilization -- Important Aspects of Normal Embryonic and Fetal Development -- Historical Perspective -- Blastocyst Formation and Differentiation of the Germ Cell Layers -- "Maternal Recognition of Pregnancy" and Implantation -- Formation of the Extraembryonic Membranes -- Concepts and Definitions -- Placental Types -- Placental Function -- The "Placental Barrier"--Sex Determination and Sexual Differentiation of Reproductive Function -- Genotypic Sex and Development of the Primitive Sex Cords -- Gonadal Sex Determination and Phenotypic Sexual Differentiation -- Development of the Male Phenotype -- Development of the Female Phenotype -- Sexual Differentiation of the Brain -- The Endocrinology of Pregnancy -- Gestational Hormones -- Parturition -- Physiology of Parturition -- The Mammary Glands -- Anatomy -- Physiology of Lactation -- Lactogenesis -- Control of Prolactin Secretion -- Reproductive Senescence -- CONCLUDING REMARKS AND FUTURE DIRECTIONS -- References -- 3 - Pharmacokinetics in Pregnancy -- INTRODUCTION -- FACTORS AFFECTING PHARMACOKINETICS IN PREGNANCY -- Absorption -- Distribution -- Metabolism -- Renal Excretion -- THE FETAL COMPARTMENT -- Drug Metabolism Within the Fetal Compartment -- Drug Accumulation Within the Fetal Compartment -- HIGHLIGHTING THE VALUE OF PK INFORMATION IN PREGNANCY: TOCOLYTIC THERAPY -- MATERNAL DISEASE AND OBSTETRICAL COMPLICATIONS -- ORIGINS OF THE KNOWLEDGE GAP -- CURRENT INITIATIVES AND FUTURE DIRECTIONS -- PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING -- CONCLUDING REMARKS AND FUTURE DIRECTIONS. 
650 0 |a Reproductive toxicology. 
650 1 2 |a Teratogens  |x toxicity  |0 (DNLM)D013723Q000633 
650 2 2 |a Congenital Abnormalities  |x embryology  |0 (DNLM)D000013Q000196 
650 2 2 |a Embryonic Development  |x drug effects  |0 (DNLM)D047108Q000187 
650 2 2 |a Fetal Development  |x drug effects  |0 (DNLM)D047109Q000187 
650 2 2 |a Toxicity Tests  |0 (DNLM)D018675 
650 6 |a Toxicologie de la reproduction.  |0 (CaQQLa)201-0189902 
650 7 |a MEDICAL  |x Toxicology.  |2 bisacsh 
650 7 |a SCIENCE  |x Chemistry  |x Toxicology.  |2 bisacsh 
650 7 |a Reproductive toxicology  |2 fast  |0 (OCoLC)fst01095012 
655 0 |a Electronic books. 
655 4 |a Internet Resources. 
700 1 |a Gupta, Ramesh C.  |q (Ramesh Chandra),  |d 1949-  |e editor. 
776 0 8 |i Print version:  |a Gupta, Ramesh C.  |t Reproductive and Developmental Toxicology.  |d Saint Louis : Elsevier Science, �2017  |z 9780128042397 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780128042397  |z Texto completo