Reproductive and developmental toxicology /

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Of the Effects of Estrogens and Progesterone During the Female Reproductive Cycle -- Oocyte/Sperm Transport, Normal Capacitation of Sperm, and Fertilization -- Transport of the Ovulated Oocyte -- Transport and Capacitation of Spermatozoa -- Transport of Spermatozoa -- Capacitation of Spermatozoa --...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Gupta, Ramesh C. (Ramesh Chandra), 1949- (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Saint Louis : Elsevier Science, 2017.
Edición:Second edition.
Temas:
Reproductive toxicology.
Teratogens > toxicity
Congenital Abnormalities > embryology
Embryonic Development > drug effects
Fetal Development > drug effects
Toxicity Tests
Toxicologie de la reproduction.
MEDICAL > Toxicology.
SCIENCE > Chemistry > Toxicology.
Reproductive toxicology
Electronic books.
Internet Resources.
Acceso en línea:Texto completo
Descripción
Sumario:Of the Effects of Estrogens and Progesterone During the Female Reproductive Cycle -- Oocyte/Sperm Transport, Normal Capacitation of Sperm, and Fertilization -- Transport of the Ovulated Oocyte -- Transport and Capacitation of Spermatozoa -- Transport of Spermatozoa -- Capacitation of Spermatozoa -- Fertilization -- Important Aspects of Normal Embryonic and Fetal Development -- Historical Perspective -- Blastocyst Formation and Differentiation of the Germ Cell Layers -- "Maternal Recognition of Pregnancy" and Implantation -- Formation of the Extraembryonic Membranes -- Concepts and Definitions -- Placental Types -- Placental Function -- The "Placental Barrier"--Sex Determination and Sexual Differentiation of Reproductive Function -- Genotypic Sex and Development of the Primitive Sex Cords -- Gonadal Sex Determination and Phenotypic Sexual Differentiation -- Development of the Male Phenotype -- Development of the Female Phenotype -- Sexual Differentiation of the Brain -- The Endocrinology of Pregnancy -- Gestational Hormones -- Parturition -- Physiology of Parturition -- The Mammary Glands -- Anatomy -- Physiology of Lactation -- Lactogenesis -- Control of Prolactin Secretion -- Reproductive Senescence -- CONCLUDING REMARKS AND FUTURE DIRECTIONS -- References -- 3 - Pharmacokinetics in Pregnancy -- INTRODUCTION -- FACTORS AFFECTING PHARMACOKINETICS IN PREGNANCY -- Absorption -- Distribution -- Metabolism -- Renal Excretion -- THE FETAL COMPARTMENT -- Drug Metabolism Within the Fetal Compartment -- Drug Accumulation Within the Fetal Compartment -- HIGHLIGHTING THE VALUE OF PK INFORMATION IN PREGNANCY: TOCOLYTIC THERAPY -- MATERNAL DISEASE AND OBSTETRICAL COMPLICATIONS -- ORIGINS OF THE KNOWLEDGE GAP -- CURRENT INITIATIVES AND FUTURE DIRECTIONS -- PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING -- CONCLUDING REMARKS AND FUTURE DIRECTIONS.
Notas:Reproductive Senescence.
Descripción Física:1 online resource (xiii, 1446 pages) : illustrations
Bibliografía:Includes bibliographical references and index.
ISBN:9780128042403
0128042400

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