Cargando…
Adverse effects of engineered nanomaterials : exposure, toxicology, and impact on human health /
Bio-nano interactions / Dana Westmeier, Shirley K. Knauer, Roland H. Stauber, Dominic Docter -- Physicochemical characterization / Kristen Rasmussen, Hubert Rauscher, Agnieszka Mech -- Toxicity tests / Maria Dusinska, Elise Rund�en-Pran, J�urgen Schnekenburger, Jun Kanno -- Com...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Academic Press,
2017.
|
| Edición: | 2nd ed. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Cover; Title page; Copyright page; Contents; Contributors; About the Editors; Preface; Section A
- Engineered nanomaterials: hazard, exposure, risk assessment; Chapter 1
- Bio-Nano Interactions; Introduction; Protein Corona on Nanoparticles; Development of the Protein Corona; Hard Corona Versus Soft Corona; The Biomolecule Corona Composition; Dynamic Formation of the Biocorona; Impact of the NP-Biomolecule Corona on Human Systems; In Vitro Studies; In Vivo Studies; Microbiome Interactions; Nanotoxicity and the Biomolecule Corona; Conclusions; Take-Home Messages; Acknowledgments; References.
- Chapter 2
- Physicochemical CharacterizationIntroduction; Overview of Key Physicochemical Parameters; Modalities of Physicochemical Characterization; Particle Size, Size Distribution, Agglomeration, and Aggregation; Shape; Specific Surface Area and Porosity; Chemical Composition, Purity, and Crystal Structure (Crystallinity); Surface Chemistry (and Contamination); Surface Charge Density and Stability in Dispersion; Dispersibility and Solubility; Dustiness; Sample Preparation and Dispersion Media; Data Collection and Interpretation; Take-Home Messages; Acknowledgments; Disclaimer; References.
- Chapter 3
- Toxicity Tests: In Vitro and In VivoIntroduction; Methods for Visualizing Cellular Uptake and Biodistribution; Evaluation of Transport and Uptake of ENM In Vitro and In Vivo; In Vitro Toxicity Tests; Cytotoxicity Tests; Limitations of In Vitro Tests; New In Vitro Test Principles; Validated Cytotoxicity Tests; Genotoxicity Tests; Ex Vivo Models; In Vivo Toxicity Testing; Toxicokinetics; Immunological Responses; Chronic Toxicity and Carcinogenicity; Considerations for Selection of Toxicity Tests: In Vitro/In Vivo Comparison; Conclusions; Take-Home Messages; Acknowledgments.
- How can Workers be Exposed to ENMs?Exposure Routes; Characterization of Behavior of ENMs; Challenges to Assess Exposure to ENMs; Exposure Assessment of ENMs in Workplaces; Evidence for Release of Engineered Nanoparticles in the Workplace; Harmful Effects on Workers; How to Measure Nanoparticles: Metrics; How to Measure Nanoparticles: Measurement Strategies; Instruments Measuring Number Concentration; Instruments Measuring Surface Concentration; Instruments Measuring Mass Concentration; Instruments Giving Indirect Estimates; Sample Collection and Characterization.