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Adverse effects of engineered nanomaterials : exposure, toxicology, and impact on human health /
Bio-nano interactions / Dana Westmeier, Shirley K. Knauer, Roland H. Stauber, Dominic Docter -- Physicochemical characterization / Kristen Rasmussen, Hubert Rauscher, Agnieszka Mech -- Toxicity tests / Maria Dusinska, Elise Rund�en-Pran, J�urgen Schnekenburger, Jun Kanno -- Com...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Academic Press,
2017.
|
| Edición: | 2nd ed. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 020 | |z 9780128094907 | ||
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| 020 | |z 9780128091999 | ||
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| 245 | 0 | 0 | |a Adverse effects of engineered nanomaterials : |b exposure, toxicology, and impact on human health / |c edited by Bengt Fadeel, Antonio Pietroiusti, Anna A. Shvedova. |
| 250 | |a 2nd ed. | ||
| 260 | |a London : |b Academic Press, |c 2017. | ||
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Cover; Title page; Copyright page; Contents; Contributors; About the Editors; Preface; Section A -- Engineered nanomaterials: hazard, exposure, risk assessment; Chapter 1 -- Bio-Nano Interactions; Introduction; Protein Corona on Nanoparticles; Development of the Protein Corona; Hard Corona Versus Soft Corona; The Biomolecule Corona Composition; Dynamic Formation of the Biocorona; Impact of the NP-Biomolecule Corona on Human Systems; In Vitro Studies; In Vivo Studies; Microbiome Interactions; Nanotoxicity and the Biomolecule Corona; Conclusions; Take-Home Messages; Acknowledgments; References. | |
| 505 | 8 | |a Chapter 2 -- Physicochemical CharacterizationIntroduction; Overview of Key Physicochemical Parameters; Modalities of Physicochemical Characterization; Particle Size, Size Distribution, Agglomeration, and Aggregation; Shape; Specific Surface Area and Porosity; Chemical Composition, Purity, and Crystal Structure (Crystallinity); Surface Chemistry (and Contamination); Surface Charge Density and Stability in Dispersion; Dispersibility and Solubility; Dustiness; Sample Preparation and Dispersion Media; Data Collection and Interpretation; Take-Home Messages; Acknowledgments; Disclaimer; References. | |
| 505 | 8 | |a Chapter 3 -- Toxicity Tests: In Vitro and In VivoIntroduction; Methods for Visualizing Cellular Uptake and Biodistribution; Evaluation of Transport and Uptake of ENM In Vitro and In Vivo; In Vitro Toxicity Tests; Cytotoxicity Tests; Limitations of In Vitro Tests; New In Vitro Test Principles; Validated Cytotoxicity Tests; Genotoxicity Tests; Ex Vivo Models; In Vivo Toxicity Testing; Toxicokinetics; Immunological Responses; Chronic Toxicity and Carcinogenicity; Considerations for Selection of Toxicity Tests: In Vitro/In Vivo Comparison; Conclusions; Take-Home Messages; Acknowledgments. | |
| 504 | |a ReferencesChapter 4-Computational Approaches; Introduction; Challenges in Modeling Nanoparticle Biological Effects; Examples of Nanotoxicology Modeling Approaches; Quantum Chemical Studies of Toxicity of Nanoparticles; Statistical Modeling and Machine Learning Methods; Nanotoxicological Fingerprints to Classify Nanomaterials; Molecular Modeling and Molecular Dynamics Methods; Elucidating Interactions Between Nanomaterials and Proteins; Other Modeling Approaches for Nanotoxicology; Conclusions; Take-Home Messages; References; Chapter 5-Exposure Assessment; Background. | ||
| 505 | 8 | |a How can Workers be Exposed to ENMs?Exposure Routes; Characterization of Behavior of ENMs; Challenges to Assess Exposure to ENMs; Exposure Assessment of ENMs in Workplaces; Evidence for Release of Engineered Nanoparticles in the Workplace; Harmful Effects on Workers; How to Measure Nanoparticles: Metrics; How to Measure Nanoparticles: Measurement Strategies; Instruments Measuring Number Concentration; Instruments Measuring Surface Concentration; Instruments Measuring Mass Concentration; Instruments Giving Indirect Estimates; Sample Collection and Characterization. | |
| 500 | |a ENM Modifications After Their Release. | ||
| 588 | 0 | |a Print version record. | |
| 520 | 0 | |a Bio-nano interactions / Dana Westmeier, Shirley K. Knauer, Roland H. Stauber, Dominic Docter -- Physicochemical characterization / Kristen Rasmussen, Hubert Rauscher, Agnieszka Mech -- Toxicity tests / Maria Dusinska, Elise Rund�en-Pran, J�urgen Schnekenburger, Jun Kanno -- Computational approaches / Tu C. Le, Vidana Epa, Lang Tran, Dave Winkler -- Exposure Assessment / Kai Savolainen, Antonio Pietroiusti -- Biomonitoring / Enrico Bergamaschi, Irirna Guseva Canu, Adriele Prina-Mello, Regulation and legislation / Kirsten Rasmussen, Brigit Sokull-Kl�uttgen, IL Je Yu, Jun Kanno, Akihiro Hirose, Maureen R. Gwinn -- Risk assessment and risk management / Robert Landsiedel, Ursula G. Sauer, Wim H De Jong -- Respiratory system, part one / Craig A. Plooand, Ken Donaldson -- Respiratory system, part two / Harri Alenius, Michael R. Shurin, Galina V. Shurin, Don Beezhold, Anna A. Shvedova -- Cardiovascular system / Jennifer B. Raftis, Nicholas L. Mills, Rodger Duffin -- Neurological system / Myrtill Simk�o, Mats-olof Mattsson, Robert A. Yokel -- Immune system / Diana Boraschi, Bengt Fadeel, Albert Duschl -- Endorine system / Xuefei Lu, Yong Zhu, Tao Zhu -- Skin / Nancy A. Monteiro-Riviere, Francesca Larese Filon -- Gastrointestinal system / Mark A. Jepson, Hans Bouwmeester -- Reproduction and development / Luisa Campagnolo, Karin S. Hougard -- Genotoxicitiy and cancer / Shareen H. Doak, Ying Liu, Chunying Chen. | |
| 650 | 0 | |a Nanostructured materials |x Toxicology. | |
| 650 | 0 | |a Risk assessment. | |
| 650 | 1 | 2 | |a Nanostructures |x adverse effects |0 (DNLM)D049329Q000009 |
| 650 | 2 | 2 | |a Nanostructures |x toxicity |0 (DNLM)D049329Q000633 |
| 650 | 2 | 2 | |a Environmental Exposure |x adverse effects |0 (DNLM)D004781Q000009 |
| 650 | 2 | 2 | |a Risk Assessment |0 (DNLM)D018570 |
| 650 | 6 | |a Nanomat�eriaux |0 (CaQQLa)201-0258061 |x Toxicologie. |0 (CaQQLa)201-0379898 | |
| 650 | 6 | |a �Evaluation du risque. |0 (CaQQLa)201-0139195 | |
| 650 | 7 | |a risk assessment. |2 aat |0 (CStmoGRI)aat300263660 | |
| 650 | 7 | |a MEDICAL |x Pharmacology. |2 bisacsh | |
| 650 | 7 | |a Risk assessment |2 fast |0 (OCoLC)fst01098146 | |
| 655 | 0 | |a Electronic books. | |
| 655 | 4 | |a Internet Resources. | |
| 655 | 4 | |a Portraits. | |
| 700 | 1 | |a Fadeel, Bengt, |e editor. | |
| 700 | 1 | |a Pietroiusti, Antonio, |e editor. | |
| 700 | 1 | |a Shvedova, Anna A., |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Adverse effects of engineered nanomaterials. |b 2nd ed. |d London : Academic Press, 2017 |z 9780128091999 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780128091999 |z Texto completo |