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Applications of Mass Spectrometry Imaging to Cancer /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Drake, Richard R. (Editor ), Mcdonnell, Liam (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cambridge, MA : Academic Press is an imprint of Elsevier, 2017.
Colección:Advances in cancer research ; v. 134.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Applications of Mass Spectrometry Imaging to Cancer /  |c edited by Richard R. Drake and Liam A. McDonnell. 
264 1 |a Cambridge, MA :  |b Academic Press is an imprint of Elsevier,  |c 2017. 
300 |a 1 online resource (xiv, 298 pages :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Advances in cancer research ;  |v volume 134 
546 |a Text in English. 
505 0 |a Front Cover; Applications of Mass Spectrometry Imaging to Cancer; Copyright; Contents; Contributors; Preface; References; Chapter One: The Importance of Histology and Pathology in Mass Spectrometry Imaging; 1. Importance of Pathology; 2. Possible Errors Caused by Tissue Inherent Factors-Why Histology Is Important for Supervised Analysis; 3. Possible Errors Caused by Sample Inherent Factors-Small Pretherapeutic Biopsies; 4. Possible Errors Caused by Sample Preparations-Artifacts Are Not Your Friend. 
505 8 |a 5. Possible Errors Caused by Ill-Defined Sample Groups in the Training Set-Keep It Black and White/Shades of Gray Are Not ... 6. Conclusion; References; Chapter Two: Applications of Mass Spectrometry Imaging to Cancer; 1. Introduction; 1.1. The Advantages of MSI; 1.2. The Basic Principles of MSI; 1.2.1. MALDI-TOF; 1.2.2. MALDI-FT-ICR; 1.2.3. SIMS-TOF; 1.2.4. DESI; 2. Protein MSI in Cancer Research; 2.1. Distinguishing Tissue Types by Peptide MSI; 2.2. Determining Tumor Margins by Peptide MSI; 2.3. Prediction of Metastasis by Peptide MSI; 2.4. Analysing Chemoresponse by Peptide MSI. 
505 8 |a 2.5. Identification of Diagnostic and Prognostic Markers by Peptide MSI2.6. Characterisation of Intra- and Intertumor Variability by Peptide MSI; 2.7. Practical Considerations for Proteolytic Peptide MSI: Sample Preparation; 2.8. Practical Considerations for Peptide MSI: Spatial Resolution; 2.9. Practical Considerations for Peptide MSI: Mass Analysers; 2.10. Practical Considerations for Peptide MSI: Identification; 3. Lipid MSI in Cancer Research; 3.1. Profiling Lipids in Cancer by DESI-MSI; 3.2. Profiling Lipids in Cancer by SIMS-MSI; 4. Glycan MSI in Cancer Research. 
505 8 |a 5. Drug Imaging in Cancer Research5.1. MALDI-MSI on Tissue Sections; 5.2. MALDI-MSI on Whole Body Sections; 5.3. MALDI-MSI on 3D Tissue Cultures; 6. Data Analysis; 6.1. Spatial Information; 6.2. Preprocessing: Peak Detection; 6.3. Classification of FFPE-TMAs and the Importance of Dimension Reduction; 7. Concluding Remarks; 7.1. The Future of MSI: Molecular Pathology; References; Chapter Three: Assessing the Potential of Metal-Assisted Imaging Mass Spectrometry in Cancer Research; 1. Introduction; 2. Material; 3. Silver-Assisted IMS; 3.1. Preparation of Silver-Coated Glass Slides. 
505 8 |a 3.2. Tissue Deposition on Silver- or ITO-Coated Slides3.3. Silver Deposition on Tissue Section; 3.4. LDI Data Acquisition of a Silver-Coated Tissue Section; 3.5. Fast Optimization of New Tissue Sections; 4. Gold-Assisted IMS; 4.1. Preparation of Gold-Coated Glass Slides; 4.2. Tissue Deposition on ITO- or Gold-Coated Slides; 4.3. Sodium Salt Deposition; 4.4. Gold Deposition on Tissue Section; 4.5. LDI Data Acquisition of a CBS-Au-Coated Tissue Section; 5. Applications to Cancer Research; 6. Concluding Remarks; References. 
500 |a Includes index. 
588 0 |a Online resource; title from title details screen (ScienceDirect, viewed January 30, 2017). 
504 |a Includes bibliographical references and index. 
650 0 |a Cancer  |x Spectroscopic imaging. 
650 0 |a Mass spectrometry. 
650 1 2 |a Mass Spectrometry  |0 (DNLM)D013058 
650 6 |a Cancer  |x Imagerie spectroscopique.  |0 (CaQQLa)201-0234723 
650 6 |a Spectrom�etrie de masse.  |0 (CaQQLa)201-0047036 
650 7 |a mass spectrometry.  |2 aat  |0 (CStmoGRI)aat300225881 
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650 7 |a MEDICAL  |x Diseases.  |2 bisacsh 
650 7 |a MEDICAL  |x Evidence-Based Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Internal Medicine.  |2 bisacsh 
650 7 |a Cancer  |x Spectroscopic imaging.  |2 fast  |0 (OCoLC)fst00845522 
650 7 |a Mass spectrometry.  |2 fast  |0 (OCoLC)fst01011435 
655 4 |a Internet Resources. 
700 1 |a Drake, Richard R.,  |e editor. 
700 1 |a Mcdonnell, Liam,  |e editor. 
776 0 8 |i Print version:  |t Applications of Mass Spectrometry Imaging to Cancer.  |d Cambridge, MA : Academic Press is an imprint of Elsevier, 2017  |z 9780128052495  |z 012805249X  |w (OCoLC)957503434 
830 0 |a Advances in cancer research ;  |v v. 134. 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/bookseries/0065230X/134  |z Texto completo