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SCIDIR_ocn970041760 |
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170126s2017 maua ob 001 0 eng d |
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|a RC255
|b .A66 2017eb
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|a HEA
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|a 616.99/40754
|2 23
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|a Applications of Mass Spectrometry Imaging to Cancer /
|c edited by Richard R. Drake and Liam A. McDonnell.
|
264 |
|
1 |
|a Cambridge, MA :
|b Academic Press is an imprint of Elsevier,
|c 2017.
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300 |
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|a 1 online resource (xiv, 298 pages :
|b illustrations
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336 |
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|a text
|b txt
|2 rdacontent
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337 |
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|a computer
|b c
|2 rdamedia
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338 |
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|a online resource
|b cr
|2 rdacarrier
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490 |
1 |
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|a Advances in cancer research ;
|v volume 134
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546 |
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|a Text in English.
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0 |
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|a Front Cover; Applications of Mass Spectrometry Imaging to Cancer; Copyright; Contents; Contributors; Preface; References; Chapter One: The Importance of Histology and Pathology in Mass Spectrometry Imaging; 1. Importance of Pathology; 2. Possible Errors Caused by Tissue Inherent Factors-Why Histology Is Important for Supervised Analysis; 3. Possible Errors Caused by Sample Inherent Factors-Small Pretherapeutic Biopsies; 4. Possible Errors Caused by Sample Preparations-Artifacts Are Not Your Friend.
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505 |
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|a 5. Possible Errors Caused by Ill-Defined Sample Groups in the Training Set-Keep It Black and White/Shades of Gray Are Not ... 6. Conclusion; References; Chapter Two: Applications of Mass Spectrometry Imaging to Cancer; 1. Introduction; 1.1. The Advantages of MSI; 1.2. The Basic Principles of MSI; 1.2.1. MALDI-TOF; 1.2.2. MALDI-FT-ICR; 1.2.3. SIMS-TOF; 1.2.4. DESI; 2. Protein MSI in Cancer Research; 2.1. Distinguishing Tissue Types by Peptide MSI; 2.2. Determining Tumor Margins by Peptide MSI; 2.3. Prediction of Metastasis by Peptide MSI; 2.4. Analysing Chemoresponse by Peptide MSI.
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|a 2.5. Identification of Diagnostic and Prognostic Markers by Peptide MSI2.6. Characterisation of Intra- and Intertumor Variability by Peptide MSI; 2.7. Practical Considerations for Proteolytic Peptide MSI: Sample Preparation; 2.8. Practical Considerations for Peptide MSI: Spatial Resolution; 2.9. Practical Considerations for Peptide MSI: Mass Analysers; 2.10. Practical Considerations for Peptide MSI: Identification; 3. Lipid MSI in Cancer Research; 3.1. Profiling Lipids in Cancer by DESI-MSI; 3.2. Profiling Lipids in Cancer by SIMS-MSI; 4. Glycan MSI in Cancer Research.
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505 |
8 |
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|a 5. Drug Imaging in Cancer Research5.1. MALDI-MSI on Tissue Sections; 5.2. MALDI-MSI on Whole Body Sections; 5.3. MALDI-MSI on 3D Tissue Cultures; 6. Data Analysis; 6.1. Spatial Information; 6.2. Preprocessing: Peak Detection; 6.3. Classification of FFPE-TMAs and the Importance of Dimension Reduction; 7. Concluding Remarks; 7.1. The Future of MSI: Molecular Pathology; References; Chapter Three: Assessing the Potential of Metal-Assisted Imaging Mass Spectrometry in Cancer Research; 1. Introduction; 2. Material; 3. Silver-Assisted IMS; 3.1. Preparation of Silver-Coated Glass Slides.
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|a 3.2. Tissue Deposition on Silver- or ITO-Coated Slides3.3. Silver Deposition on Tissue Section; 3.4. LDI Data Acquisition of a Silver-Coated Tissue Section; 3.5. Fast Optimization of New Tissue Sections; 4. Gold-Assisted IMS; 4.1. Preparation of Gold-Coated Glass Slides; 4.2. Tissue Deposition on ITO- or Gold-Coated Slides; 4.3. Sodium Salt Deposition; 4.4. Gold Deposition on Tissue Section; 4.5. LDI Data Acquisition of a CBS-Au-Coated Tissue Section; 5. Applications to Cancer Research; 6. Concluding Remarks; References.
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500 |
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|a Includes index.
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588 |
0 |
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|a Online resource; title from title details screen (ScienceDirect, viewed January 30, 2017).
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504 |
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|a Includes bibliographical references and index.
|
650 |
|
0 |
|a Cancer
|x Spectroscopic imaging.
|
650 |
|
0 |
|a Mass spectrometry.
|
650 |
1 |
2 |
|a Mass Spectrometry
|0 (DNLM)D013058
|
650 |
|
6 |
|a Cancer
|x Imagerie spectroscopique.
|0 (CaQQLa)201-0234723
|
650 |
|
6 |
|a Spectrom�etrie de masse.
|0 (CaQQLa)201-0047036
|
650 |
|
7 |
|a mass spectrometry.
|2 aat
|0 (CStmoGRI)aat300225881
|
650 |
|
7 |
|a HEALTH & FITNESS
|x Diseases
|x General.
|2 bisacsh
|
650 |
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7 |
|a MEDICAL
|x Clinical Medicine.
|2 bisacsh
|
650 |
|
7 |
|a MEDICAL
|x Diseases.
|2 bisacsh
|
650 |
|
7 |
|a MEDICAL
|x Evidence-Based Medicine.
|2 bisacsh
|
650 |
|
7 |
|a MEDICAL
|x Internal Medicine.
|2 bisacsh
|
650 |
|
7 |
|a Cancer
|x Spectroscopic imaging.
|2 fast
|0 (OCoLC)fst00845522
|
650 |
|
7 |
|a Mass spectrometry.
|2 fast
|0 (OCoLC)fst01011435
|
655 |
|
4 |
|a Internet Resources.
|
700 |
1 |
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|a Drake, Richard R.,
|e editor.
|
700 |
1 |
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|a Mcdonnell, Liam,
|e editor.
|
776 |
0 |
8 |
|i Print version:
|t Applications of Mass Spectrometry Imaging to Cancer.
|d Cambridge, MA : Academic Press is an imprint of Elsevier, 2017
|z 9780128052495
|z 012805249X
|w (OCoLC)957503434
|
830 |
|
0 |
|a Advances in cancer research ;
|v v. 134.
|
856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/bookseries/0065230X/134
|z Texto completo
|