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Polycomb group proteins /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Pirrotta, Vincenzo (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, 2017.
Colección:Translational epigenetics series.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Polycomb group proteins /  |c edited by Vincenzo Pirrotta. 
260 |a London :  |b Academic Press,  |c 2017. 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Translational epigenetics series 
504 |a Includes bibliographical references and index. 
588 0 |a Online resource, title from PDF title page (EBSCO, viewed January 28, 2017). 
505 0 |a Front Cover; Polycomb Group Proteins; Translational Epigenetics Series; Polycomb Group Proteins; Copyright; Contents; List of Contributors; Editor's Biography; Acknowledgments; 1 -- Introduction to Polycomb Group Mechanisms; REFERENCES; 2 -- The Role of RAWUL and SAM in Polycomb Repression Complex 1 Assembly and Function; INTRODUCTION; POLYCOMB GROUP; POLYCOMB GROUP RAWUL; Structural Basis for RAWUL-Binding Selectivity; RAWUL Heterodimerization as a Template for Additional Interactions; Internal Tandem Duplications in BCOR PUFD Found in Tumors; POLYCOMB GROUP SAMS. 
505 8 |a Ph SAM Polymerization Is Required for FunctionPh SAM Polymerization Is Required for Subnuclear Organization of PRC1; What Is the Stoichiometry of SAM-Polymerized PRC1?; SAM Polymer Regulation; How Does Ph SAM Polymerization Affect PRC1 H2Aub Activity?; Scm SAM-Dependent Repression; SUMMARY; LIST OF ACRONYMS AND ABBREVIATIONS; ACKNOWLEDGMENTS; REFERENCES; 3 -- The Chromodomain of Polycomb: Methylation Reader and Beyond; INTRODUCTION; POLYCOMB CHROMODOMAIN SPECIFICALLY RECOGNIZES H3K27ME3; STRUCTURAL BASIS FOR THE POLYCOMB-H3K27ME3 INTERACTION SPECIFICITY. 
505 8 |a MAMMALIAN POLYCOMB HOMOLOGS BIND DIFFERENTIALLY TO METHYLATED HISTONE H3CROSS TALK BETWEEN HISTONE METHYLATION AND OTHER POSTTRANSLATIONAL MODIFICATIONS; PUTATIVE NONHISTONE TARGETS OF POLYCOMB GROUP CHROMODOMAINS; NONCODING RNA: NONCANONICAL PARTNERS OF POLYCOMB GROUP CHROMODOMAINS; CHEMICAL PROBES FOR CBX7 CHROMODOMAIN; POLYCOMB HOMOLOGS FROM YEAST AND PLANT: EVOLUTIONARILY CONSERVED BIOLOGICAL SIGNIFICANCE OF CHROMODOMAIN; CONCLUSION; LIST OF ACRONYMS AND ABBREVIATIONS; GLOSSARY; REFERENCES; 4 -- Unraveling the Roles of Canonical and Noncanonical PRC1 Complexes; BACKGROUND. 
505 8 |a THE MECHANISM OF ACTION OF CANONICAL POLYCOMB REPRESSIVE COMPLEXES 1THE MECHANISM OF ACTION OF NONCANONICAL POLYCOMB REPRESSIVE COMPLEXES 1; THE BIOLOGICAL IMPORTANCE OF CANONICAL POLYCOMB REPRESSIVE COMPLEX 1, NONCANONICAL POLYCOMB REPRESSIVE COMPLEX 1, AND H2A M ... ; PERSPECTIVES; LIST OF ACRONYMS AND ABBREVIATIONS; REFERENCES; 5 -- Structure and Biochemistry of the Polycomb Repressive Complex 1 Ubiquitin Ligase Module; INTRODUCTION; UBIQUITIN CONJUGATION AND DECONJUGATION; PRC1 IS A RING E3 LIGASE; THE ACTIVE E3 LIGASE IS A HETERODIMER OF BMI1 AND RING1. 
505 8 |a BIOCHEMICAL AND STRUCTURAL STUDIES OF THE RING DOMAINS OF THE BMI1-RING1B HETERODIMERRECOGNITION OF E2 ENZYMES BY BMI1-RING1B; INTERACTION OF BMI1-RING1B-UBCH5C WITH SUBSTRATE; STRUCTURE OF THE PRC1 UBIQUITIN LIGASE MODULE BOUND TO NUCLEOSOME; VARIANT PRC1 COMPLEXES AND THE MECHANISM OF UBIQUITIN TRANSFER; WHICH PRC1 CONTRIBUTES MOST TO H2A UBIQUITINATION?; IS H2A UBIQUITINATION REALLY IMPORTANT?; WHAT DOES UH2A DO?; WHAT'S NEXT FOR PRC1 AND UH2A?; REFERENCES; 6 -- Cooperative Recruitment of Polycomb Complexes by Polycomb Response Elements; INTRODUCTION; POLYCOMB GROUP PROTEIN COMPLEXES. 
650 0 |a Proteins. 
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700 1 |a Pirrotta, Vincenzo,  |e editor. 
776 0 8 |i Print version:  |t Polycomb group proteins.  |d London : Academic Press, 2017  |z 9780128097373  |z 012809737X  |w (OCoLC)957503545 
830 0 |a Translational epigenetics series. 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780128097373  |z Texto completo