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170106s2017 mau o 000 0 eng d |
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|a T-box genes in development and disease /
|c edited by Manfred Frasch.
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| 260 |
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|a Cambridge, MA :
|b Academic Press,
|c 2017.
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| 300 |
|
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|a 1 online resource
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| 336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
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1 |
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|a Current topics in developmental biology ;
|v volume 122
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|a Print version record.
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|a Front Cover; T-box Genes in Development; Copyright; Contents; Contributors; Preface; References; Chapter One: Evolution and Classification of the T-Box Transcription Factor Family; 1. An Updated Phylogenetic Classification of the T-Box Gene Family; 2. Premetazoan T-Box Genes; 3. Metazoan T-Box Classes and Function; 3.1. Brachyury; 3.2. Eomes/Tbrain; 3.3. Tbx7; 3.4. Tbx8; 3.5. Tbx2/3; 3.6. Tbx4/5; 3.7. Tbx1/15/20; 3.8. Tbx6; 4. Functional Conservation of Premetazoan and Early-Metazoan Brachyury Homologs; 5. Ancestral Conserved Role of Brachyury in Morphogenetic Movements.
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| 505 |
8 |
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|a 6. The Evolution of T-Box RegulationAcknowledgments; References; Chapter Two: The Remarkably Diverse Family of T-Box Factors in Caenorhabditis elegans; 1. Introduction; 2. T-Box Genes in C. elegans and Related Nematodes; 3. DNA-Binding Specificity of C. elegans T-Box Factors; 4. Genetic Analyses of T-Box Factor Function in C. elegans; 4.1. A Network of T-Box Factors Function in C. elegans Pharyngeal Development; 4.2. tbx-2 Has Additional Functions in Neuronal Development and Sensory Adaptation.
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|a 4.3. The Tbx-1 Subfamily Members MAB-9 and MLS-1 Function Postembryonically to Specify Ectodermal and Muscle Cell Fates4.4. The TBX-8 and TBX-9 Paralogs Play Redundant Roles in Hypodermal and Body Wall Muscle Morphogenesis; 4.5. The Divergent T-Box Factor SEA-1 Functions as an Autosomal Counting Element to Determine Sex in C. elegans; 4.6. The Functions of Other C. elegans T-Box Genes Are Only Beginning to Be Characterized; 5. Posttranslational Mechanisms Affecting T-Box Factor Activity; 6. Concluding Remarks; Acknowledgments; References.
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|a Chapter Three: T-Box Genes and Developmental Gene Regulatory Networks in Ascidians1. Introduction; 2. Brachyury and the Temporal Control of Notochord Specification, Development, and Differentiation; 3. Tbx2/3: An Essential Mediator of Brachyury Function in the Notochord; 4. The Lineage-Specific Duplication of Tbx6 Genes in Ascidians; 5. Tbx6a; 6. Tbx6b, Tbx6c, and the Interpretation of the Maternally Inherited Muscle Determinant; 7. Tbx6b and Tbx6c in Heart Development; 8. Tbx1/10 and the Evolutionary Origins of the Pharyngeal Muscles.
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| 505 |
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|a 9. Tbx15/18/22 (VegTR) and the Establishment of Muscle Cell Identity10. Maternal T and Tail Development; 11. Tbx20: In or Out of the Ascidian Heart?; 12. Transcriptional Regulation of T-Box Genes Expression; 12.1. Brachyury: A Balancing Act Between Multiple Activators and a Repressor; 12.2. Tbx2/3: A Composite Expression Pattern Orchestrated by Additive, Partly Redundant CRMs; 12.3. Tbx6b and Tbx6c: Early and Late Elements, Autoregulation, and Crossregulation; 13. Concluding Remarks; Acknowledgments; References.
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| 504 |
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|a Includes bibliographical references and index.
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| 650 |
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0 |
|a Genes.
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| 650 |
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0 |
|a Developmental genetics.
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| 650 |
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0 |
|a Medical genetics.
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| 650 |
1 |
2 |
|a T-Box Domain Proteins
|0 (DNLM)D020825
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| 650 |
2 |
2 |
|a Embryonic Development
|x genetics
|0 (DNLM)D047108Q000235
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| 650 |
2 |
2 |
|a Gene Expression Regulation, Developmental
|0 (DNLM)D018507
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| 650 |
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2 |
|a Genes
|0 (DNLM)D005796
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| 650 |
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2 |
|a Genetics, Medical
|0 (DNLM)D005826
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| 650 |
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6 |
|a G�enes.
|0 (CaQQLa)201-0008512
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| 650 |
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6 |
|a G�en�etique du d�eveloppement.
|0 (CaQQLa)201-0008942
|
| 650 |
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6 |
|a G�en�etique m�edicale.
|0 (CaQQLa)201-0001432
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| 650 |
|
7 |
|a SCIENCE
|x Life Sciences
|x Biochemistry.
|2 bisacsh
|
| 650 |
|
7 |
|a Developmental genetics.
|2 fast
|0 (OCoLC)fst00891808
|
| 650 |
|
7 |
|a Genes.
|2 fast
|0 (OCoLC)fst00939991
|
| 650 |
|
7 |
|a Medical genetics.
|2 fast
|0 (OCoLC)fst01014133
|
| 700 |
1 |
|
|a Frasch, Manfred,
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|t T-box genes in development and disease.
|d Cambridge, MA : Academic Press, 2017
|z 012801380X
|z 9780128013809
|w (OCoLC)959033404
|
| 830 |
|
0 |
|a Current topics in developmental biology ;
|v v. 122.
|
| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/bookseries/00702153/122
|z Texto completo
|
