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Congenital and acquired bone marrow failure /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Gluckman, Eliane, Dufour, C., Aljurf, Mahmoud Deeb
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, 2017.
Temas:
Acceso en línea:Texto completo

MARC

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035 |a (OCoLC)967393718  |z (OCoLC)967254553  |z (OCoLC)968341581 
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060 4 |a 2017 C-814 
060 4 |a WH 380 
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245 0 0 |a Congenital and acquired bone marrow failure /  |c edited by M.D. Aljurf, E. Gluckman, C. Dufour. 
260 |a London :  |b Academic Press,  |c 2017. 
300 |a 1 online resource (290) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
588 0 |a Print version record. 
505 0 |a Cover; Title page; Copyright page; Contents; List of Contributors; Introduction; Chapter 1 -- Epidemiology of Acquired Bone Marrow Failure; Introduction; Incidence of AA in different geographical regions and race; Age and gender related demographics of AA; Posthepatitis AA and AA occurring after viral infections; AA and association with toxins/drugs; AA and association with HLA genes; AA and autoimmune disorders; AA during pregnancy; AA postvaccination; Problems with epidemiological studies in AA and future strategies; References; Chapter 2 -- Pathophysiology of Acquired Bone Marrow Failure. 
505 8 |a Introduction: Evidence and Inferences from the ClinicPathophysiology; Hematopoiesis in AA; Immune Mechanisms in AA; Clinical Data; T Cells and Cytokines; HLA and Cytokine Gene Polymorphisms; Immune Escape Clones (PNH, 6pLOH); STAT3 Mutant Clones; Innate Immunity; microRNAs; Autoantibodies; Immune-Mediated BM Failure Mouse Models; Mouse Models of Chemical and Drug Hematopoietic Toxicity; Genetic Risk Factors in AA; Clonal Evolution in AA; Treatments for AA; BMT With Matched Sibling Donors; BMT From Alternative Donors; Experimental HSCT; IST; Eltrombopag; Supportive Care; Conclusions. 
505 8 |a AA and HLA-DR TypingAA and LGL; Diagnostic of AA in the Elderly; Defining Severity of AA; Defining Response After Treatment; Future challenges in the diagnostics of AA; Acknowledgment; References; Chapter 4 -- Acquired Overlap Bone Marrow Failure Disorders; Introduction; Hypoplastic MDS; Single lineage cytopenias (pure red cell aplasia or immune thrombocytopenia); T cell large granular lymphocytes; Paroxysmal nocturnal hemoglobinuria; Congenital marrow failure undiagnosed; Conclusions; References; Chapter 5 -- Supportive Care in Aplastic Anemia; Introduction. 
505 8 |a Prevention of infections by general medical management of aplastic anemia patientsProtective Environment; Protective Isolation; Special Low Bacterial Diet; Individual Hygiene Rules; Prevention of infections by antibiotic/antimycotic/antiviral prophylaxis; Antimycotic Prophylaxis; Antibiotic Prophylaxis; Antiviral Prophylaxis; Vaccination; Hematopoietic growth factors as prophylaxis of infections or in combination with immunosuppression to improve quality of re ... ; Treatment of infections; Granulocyte Transfusions; Transfusion therapy; Iron chelation therapy; Physical exercise. 
504 |a Includes bibliographical references and index. 
650 0 |a Bone marrow  |x Diseases. 
650 2 |a Bone Marrow Diseases  |0 (DNLM)D001855 
650 6 |a Moelle osseuse  |x Maladies.  |0 (CaQQLa)201-0015076 
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650 7 |a MEDICAL  |x Clinical Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Diseases.  |2 bisacsh 
650 7 |a MEDICAL  |x Evidence-Based Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Internal Medicine.  |2 bisacsh 
650 7 |a Bone marrow  |x Diseases  |2 fast  |0 (OCoLC)fst00835945 
655 0 |a Electronic books. 
655 4 |a Internet Resources. 
700 1 |a Gluckman, Eliane. 
700 1 |a Dufour, C. 
700 1 |a Aljurf, Mahmoud Deeb. 
776 0 8 |i Print version:  |z 0128041528  |z 9780128041529  |w (OCoLC)957680589 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780128041529  |z Texto completo