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161230s2017 enk ob 001 0 eng d |
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|a IDEBK
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|a GBB715315
|2 bnb
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|a 018161898
|2 Uk
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|a 967254553
|a 968341581
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|a 0128041757
|q (ebk)
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|a 9780128041758
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|z 9780128041529
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|z 0128041528
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|a (OCoLC)967393718
|z (OCoLC)967254553
|z (OCoLC)968341581
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|a RC641.7.A6
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|a 2017 C-814
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|a WH 380
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|a 616.1/52
|2 23
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|a Congenital and acquired bone marrow failure /
|c edited by M.D. Aljurf, E. Gluckman, C. Dufour.
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|a London :
|b Academic Press,
|c 2017.
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|a 1 online resource (290)
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336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Print version record.
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|a Cover; Title page; Copyright page; Contents; List of Contributors; Introduction; Chapter 1 -- Epidemiology of Acquired Bone Marrow Failure; Introduction; Incidence of AA in different geographical regions and race; Age and gender related demographics of AA; Posthepatitis AA and AA occurring after viral infections; AA and association with toxins/drugs; AA and association with HLA genes; AA and autoimmune disorders; AA during pregnancy; AA postvaccination; Problems with epidemiological studies in AA and future strategies; References; Chapter 2 -- Pathophysiology of Acquired Bone Marrow Failure.
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|a Introduction: Evidence and Inferences from the ClinicPathophysiology; Hematopoiesis in AA; Immune Mechanisms in AA; Clinical Data; T Cells and Cytokines; HLA and Cytokine Gene Polymorphisms; Immune Escape Clones (PNH, 6pLOH); STAT3 Mutant Clones; Innate Immunity; microRNAs; Autoantibodies; Immune-Mediated BM Failure Mouse Models; Mouse Models of Chemical and Drug Hematopoietic Toxicity; Genetic Risk Factors in AA; Clonal Evolution in AA; Treatments for AA; BMT With Matched Sibling Donors; BMT From Alternative Donors; Experimental HSCT; IST; Eltrombopag; Supportive Care; Conclusions.
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|a AA and HLA-DR TypingAA and LGL; Diagnostic of AA in the Elderly; Defining Severity of AA; Defining Response After Treatment; Future challenges in the diagnostics of AA; Acknowledgment; References; Chapter 4 -- Acquired Overlap Bone Marrow Failure Disorders; Introduction; Hypoplastic MDS; Single lineage cytopenias (pure red cell aplasia or immune thrombocytopenia); T cell large granular lymphocytes; Paroxysmal nocturnal hemoglobinuria; Congenital marrow failure undiagnosed; Conclusions; References; Chapter 5 -- Supportive Care in Aplastic Anemia; Introduction.
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|a Prevention of infections by general medical management of aplastic anemia patientsProtective Environment; Protective Isolation; Special Low Bacterial Diet; Individual Hygiene Rules; Prevention of infections by antibiotic/antimycotic/antiviral prophylaxis; Antimycotic Prophylaxis; Antibiotic Prophylaxis; Antiviral Prophylaxis; Vaccination; Hematopoietic growth factors as prophylaxis of infections or in combination with immunosuppression to improve quality of re ... ; Treatment of infections; Granulocyte Transfusions; Transfusion therapy; Iron chelation therapy; Physical exercise.
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|a Includes bibliographical references and index.
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650 |
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|a Bone marrow
|x Diseases.
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650 |
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2 |
|a Bone Marrow Diseases
|0 (DNLM)D001855
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650 |
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|a Moelle osseuse
|x Maladies.
|0 (CaQQLa)201-0015076
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650 |
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|a HEALTH & FITNESS
|x Diseases
|x General.
|2 bisacsh
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650 |
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|a MEDICAL
|x Clinical Medicine.
|2 bisacsh
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650 |
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|a MEDICAL
|x Diseases.
|2 bisacsh
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|a MEDICAL
|x Evidence-Based Medicine.
|2 bisacsh
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|a MEDICAL
|x Internal Medicine.
|2 bisacsh
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650 |
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|a Bone marrow
|x Diseases
|2 fast
|0 (OCoLC)fst00835945
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655 |
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|a Electronic books.
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655 |
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|a Internet Resources.
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700 |
1 |
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|a Gluckman, Eliane.
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700 |
1 |
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|a Dufour, C.
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700 |
1 |
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|a Aljurf, Mahmoud Deeb.
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776 |
0 |
8 |
|i Print version:
|z 0128041528
|z 9780128041529
|w (OCoLC)957680589
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856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128041529
|z Texto completo
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