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LEADER 00000cam a2200000Ia 4500
001 SCIDIR_ocn967258286
003 OCoLC
005 20231120112203.0
006 m o d
007 cr |n|||||||||
008 161229s2017 enk ob 001 0 eng d
040 |a YDX  |b eng  |e pn  |c YDX  |d N$T  |d EBLCP  |d OPELS  |d N$T  |d IDEBK  |d OCLCF  |d OCLCQ  |d UPM  |d OCLCQ  |d OTZ  |d MERUC  |d OCLCO  |d MERER  |d OCLCO  |d OCLCQ  |d CASUM  |d CHVBK  |d OCLCO  |d WY@  |d OCLCO  |d OCLCQ  |d OCLCO  |d OCLCQ  |d OCLCO  |d OCLCQ  |d OCLCO  |d D6H  |d OCLCO  |d OCLCQ  |d U3W  |d OCLCQ  |d OCLCO  |d OCLCQ  |d OCLCA  |d OCLCQ  |d S2H  |d OCLCO  |d OCL  |d OCLCA  |d OCL  |d OCLCO  |d OCLCA 
020 |a 9780128095027  |q (electronic bk.) 
020 |a 0128095024  |q (electronic bk.) 
020 |z 9780128094112 
020 |z 0128094117 
035 |a (OCoLC)967258286 
050 4 |a R858 
060 4 |a 2017 C-603 
060 4 |a WB 102 
072 7 |a HEA  |x 012000  |2 bisacsh 
072 7 |a HEA  |x 020000  |2 bisacsh 
072 7 |a MED  |x 004000  |2 bisacsh 
072 7 |a MED  |x 101000  |2 bisacsh 
072 7 |a MED  |x 109000  |2 bisacsh 
072 7 |a MED  |x 029000  |2 bisacsh 
072 7 |a MED  |x 040000  |2 bisacsh 
072 7 |a MED  |x 092000  |2 bisacsh 
082 0 4 |a 610.285  |2 23 
245 0 0 |a Progress and challenges in precision medicine /  |c edited by Mukesh Verma, Debmalya Barh. 
260 |a London, United Kingdom :  |b Academic Press,  |c 2017. 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
588 0 |a Online resource, title from PDF title page (EBSCO, viewed January 25, 2017). 
505 0 |a Front Cover; Progress and Challengesin Precision Medicine; Progress and Challenges in Precision Medicine; Copyright; Contents; List of Contributors; Biography; MUKESH VERMA; DEBMALYA BARH; Dedication; Preface; 1 -- Introduction: Every Individual Is Different and Precision Medicine Offers Options for Disease Control and Treatment; 1. WHAT IS PRECISION MEDICINE? PERSONALIZED MEDICINE VERSUS PRECISION MEDICINE (C. HIZEL, P. HAMET, AND J. TREMBLAY); 1.1 Precision Medicine in Complex Chronic Disease: A Focus on Diabetes; 2. PRECISION MEDICINE FOR POPULATION HEALTH (G. BARTLETT); 3. CONCLUSION 
505 8 |a 5.4 Noninvasive Prenatal Testing5.5 Disease Gene Identification; 6. REGULATORY CONCERNS WITH NGS CLINICAL GENOMICS; 7. CONCLUSION; REFERENCES; 3 -- Phenotyping in Precision Medicine; 1. INTRODUCTION; 2. DEEP PHENOTYPING; 3. EXPRESSIVITY AND PENETRANCE; 4. EXPRESSIVITY; 5. PENETRANCE; 6. PHENOTYPIC VARIATION IN EXPRESSIVITY AND PENETRANCE; 7. PLEIOTROPY; 8. DISEASES AND PHENOTYPES; 9. CANCER; 10. DIABETES; 11. RESPIRATORY DISORDERS; 12. ENCEPHALOPATHY; 13. DATA MINING AND PHENOTYPING; 14. APPROACHES FOR PHENOTYPING; 15. FUTURE DIRECTIONS; REFERENCES 
505 8 |a 4 -- Cancer Genetic Screening and Ethical Considerations for Precision Medicine1. INTRODUCTION; 2. GENETIC TESTING IN HEREDITARY CANCERS; 2.1 Genetic Testing for Hereditary Breast and Ovarian Cancers; 2.2 Genetic Testing for Hereditary Colorectal Cancers; 2.3 Genetic Testing for Lung Cancers; 3. ETHICAL ISSUES RELATED TO CANCER GENETIC SCREENING; 3.1 Competency of Genetic Screening Laboratories and Medical Personnel; 3.2 Direct-To-Consumers Genetic Testing; 3.3 Individual Rights Versus Community Rights; 3.4 Individual Informed Consent; 3.5 Return of the Results for Pediatric Patients 
505 8 |a 3.6 Environmental and Distributive Justice3.7 Cancer Screening and Discrimination; 3.8 Cancer Screening and Stigma; 3.9 Implications of Genetic-Based Cancer Screening at the Population Level; 4. SUMMARY AND CONCLUSIONS; REFERENCES; 5 -- Precision Medicine in Primary Health Care; 1. THE CASE FOR PRIMARY HEALTH CARE; 2. PRECISION MEDICINE IN PRIMARY HEALTH CARE: WARFARIN AND PHARMACOGENOMICS; 3. PRECISION MEDICINE IN PRIMARY HEALTH CARE: CREATING AN INFORMATICS SYSTEM; 4. PRECISION MEDICINE: A FEASIBILITY STUDY FOR PRIMARY HEALTH CARE; 4.1 Outcomes; 4.2 Statistical Analysis; 4.3 Ethics 
650 0 |a Medical innovations. 
650 0 |a Medical informatics. 
650 0 |a Medicine  |x Data processing. 
650 0 |a Precision medicine. 
650 1 2 |a Precision Medicine  |0 (DNLM)D057285 
650 2 2 |a Medical Informatics  |0 (DNLM)D008490 
650 2 |a Medical Informatics Applications  |0 (DNLM)D008491 
650 6 |a M�edecine  |x Innovations.  |0 (CaQQLa)201-0046524 
650 6 |a M�edecine  |x Informatique.  |0 (CaQQLa)201-0103112 
650 6 |a M�edecine de pr�ecision.  |0 (CaQQLa)000288678 
650 7 |a HEALTH & FITNESS  |x Holism.  |2 bisacsh 
650 7 |a HEALTH & FITNESS  |x Reference.  |2 bisacsh 
650 7 |a MEDICAL  |x Alternative Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Atlases.  |2 bisacsh 
650 7 |a MEDICAL  |x Essays.  |2 bisacsh 
650 7 |a MEDICAL  |x Family & General Practice.  |2 bisacsh 
650 7 |a MEDICAL  |x Holistic Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Osteopathy.  |2 bisacsh 
650 7 |a Precision medicine  |2 fast  |0 (OCoLC)fst01910010 
650 7 |a Medicine  |x Data processing  |2 fast  |0 (OCoLC)fst01014924 
650 7 |a Medical informatics  |2 fast  |0 (OCoLC)fst01014175 
650 7 |a Medical innovations  |2 fast  |0 (OCoLC)fst01014181 
655 0 |a Computer network resources. 
655 4 |a Fulltext. 
655 4 |a Internet Resources. 
700 1 |a Verma, Mukesh,  |e editor. 
700 1 |a Barh, Debmalya,  |e editor. 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780128094112  |z Texto completo