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161229s2017 enk ob 001 0 eng d |
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|a YDX
|b eng
|e pn
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|a 9780128095027
|q (electronic bk.)
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|a 0128095024
|q (electronic bk.)
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|z 9780128094112
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|z 0128094117
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|a (OCoLC)967258286
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|a R858
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|a 2017 C-603
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|a WB 102
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|a HEA
|x 012000
|2 bisacsh
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|a HEA
|x 020000
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|a MED
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|a 610.285
|2 23
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|a Progress and challenges in precision medicine /
|c edited by Mukesh Verma, Debmalya Barh.
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|a London, United Kingdom :
|b Academic Press,
|c 2017.
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|a 1 online resource
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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338 |
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|a online resource
|b cr
|2 rdacarrier
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|a Includes bibliographical references and index.
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|a Online resource, title from PDF title page (EBSCO, viewed January 25, 2017).
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|a Front Cover; Progress and Challengesin Precision Medicine; Progress and Challenges in Precision Medicine; Copyright; Contents; List of Contributors; Biography; MUKESH VERMA; DEBMALYA BARH; Dedication; Preface; 1 -- Introduction: Every Individual Is Different and Precision Medicine Offers Options for Disease Control and Treatment; 1. WHAT IS PRECISION MEDICINE? PERSONALIZED MEDICINE VERSUS PRECISION MEDICINE (C. HIZEL, P. HAMET, AND J. TREMBLAY); 1.1 Precision Medicine in Complex Chronic Disease: A Focus on Diabetes; 2. PRECISION MEDICINE FOR POPULATION HEALTH (G. BARTLETT); 3. CONCLUSION
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|a 5.4 Noninvasive Prenatal Testing5.5 Disease Gene Identification; 6. REGULATORY CONCERNS WITH NGS CLINICAL GENOMICS; 7. CONCLUSION; REFERENCES; 3 -- Phenotyping in Precision Medicine; 1. INTRODUCTION; 2. DEEP PHENOTYPING; 3. EXPRESSIVITY AND PENETRANCE; 4. EXPRESSIVITY; 5. PENETRANCE; 6. PHENOTYPIC VARIATION IN EXPRESSIVITY AND PENETRANCE; 7. PLEIOTROPY; 8. DISEASES AND PHENOTYPES; 9. CANCER; 10. DIABETES; 11. RESPIRATORY DISORDERS; 12. ENCEPHALOPATHY; 13. DATA MINING AND PHENOTYPING; 14. APPROACHES FOR PHENOTYPING; 15. FUTURE DIRECTIONS; REFERENCES
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|a 4 -- Cancer Genetic Screening and Ethical Considerations for Precision Medicine1. INTRODUCTION; 2. GENETIC TESTING IN HEREDITARY CANCERS; 2.1 Genetic Testing for Hereditary Breast and Ovarian Cancers; 2.2 Genetic Testing for Hereditary Colorectal Cancers; 2.3 Genetic Testing for Lung Cancers; 3. ETHICAL ISSUES RELATED TO CANCER GENETIC SCREENING; 3.1 Competency of Genetic Screening Laboratories and Medical Personnel; 3.2 Direct-To-Consumers Genetic Testing; 3.3 Individual Rights Versus Community Rights; 3.4 Individual Informed Consent; 3.5 Return of the Results for Pediatric Patients
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|a 3.6 Environmental and Distributive Justice3.7 Cancer Screening and Discrimination; 3.8 Cancer Screening and Stigma; 3.9 Implications of Genetic-Based Cancer Screening at the Population Level; 4. SUMMARY AND CONCLUSIONS; REFERENCES; 5 -- Precision Medicine in Primary Health Care; 1. THE CASE FOR PRIMARY HEALTH CARE; 2. PRECISION MEDICINE IN PRIMARY HEALTH CARE: WARFARIN AND PHARMACOGENOMICS; 3. PRECISION MEDICINE IN PRIMARY HEALTH CARE: CREATING AN INFORMATICS SYSTEM; 4. PRECISION MEDICINE: A FEASIBILITY STUDY FOR PRIMARY HEALTH CARE; 4.1 Outcomes; 4.2 Statistical Analysis; 4.3 Ethics
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650 |
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0 |
|a Medical innovations.
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650 |
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0 |
|a Medical informatics.
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650 |
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0 |
|a Medicine
|x Data processing.
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650 |
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0 |
|a Precision medicine.
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650 |
1 |
2 |
|a Precision Medicine
|0 (DNLM)D057285
|
650 |
2 |
2 |
|a Medical Informatics
|0 (DNLM)D008490
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650 |
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2 |
|a Medical Informatics Applications
|0 (DNLM)D008491
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650 |
|
6 |
|a M�edecine
|x Innovations.
|0 (CaQQLa)201-0046524
|
650 |
|
6 |
|a M�edecine
|x Informatique.
|0 (CaQQLa)201-0103112
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650 |
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6 |
|a M�edecine de pr�ecision.
|0 (CaQQLa)000288678
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650 |
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7 |
|a HEALTH & FITNESS
|x Holism.
|2 bisacsh
|
650 |
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7 |
|a HEALTH & FITNESS
|x Reference.
|2 bisacsh
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650 |
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7 |
|a MEDICAL
|x Alternative Medicine.
|2 bisacsh
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650 |
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7 |
|a MEDICAL
|x Atlases.
|2 bisacsh
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650 |
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7 |
|a MEDICAL
|x Essays.
|2 bisacsh
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650 |
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7 |
|a MEDICAL
|x Family & General Practice.
|2 bisacsh
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650 |
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7 |
|a MEDICAL
|x Holistic Medicine.
|2 bisacsh
|
650 |
|
7 |
|a MEDICAL
|x Osteopathy.
|2 bisacsh
|
650 |
|
7 |
|a Precision medicine
|2 fast
|0 (OCoLC)fst01910010
|
650 |
|
7 |
|a Medicine
|x Data processing
|2 fast
|0 (OCoLC)fst01014924
|
650 |
|
7 |
|a Medical informatics
|2 fast
|0 (OCoLC)fst01014175
|
650 |
|
7 |
|a Medical innovations
|2 fast
|0 (OCoLC)fst01014181
|
655 |
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0 |
|a Computer network resources.
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655 |
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4 |
|a Fulltext.
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655 |
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4 |
|a Internet Resources.
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700 |
1 |
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|a Verma, Mukesh,
|e editor.
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700 |
1 |
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|a Barh, Debmalya,
|e editor.
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856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128094112
|z Texto completo
|