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|z (OCoLC)962323885
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|a 615.7/04
|2 23
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| 245 |
0 |
2 |
|a A comprehensive guide to toxicology in nonclinical drug development /
|c edited by Ali Said Faqi.
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| 250 |
|
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|a Second edition.
|
| 264 |
|
1 |
|a London, United Kingdom :
|b Academic Press is an imprint of Elsevier,
|c [2016]
|
| 264 |
|
4 |
|c �2017
|
| 300 |
|
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|a 1 online resource (xiii, 971 pages)
|
| 336 |
|
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|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia
|
| 338 |
|
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|a online resource
|b cr
|2 rdacarrier
|
| 500 |
|
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|a Includes index.
|
| 588 |
0 |
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|a Online resource; title from PDF title page (ScienceDirect, viewed November 22, 2016).
|
| 505 |
0 |
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|a 1. Introduction; 2. ADME in Drug Discovery; 3. Pharmacokinetics and Toxicokinetics; 4. Acute, Sub-Acute, Sub-Chronic and Chronic, Dermal and Inhalation Toxicology; 5. Contemporary Practices in Core Safety Pharmacology Assessments; 6. Genetic Toxicology Testing; 7. Clinical Pathology; 8. Best Practice in Toxicologic Pathology; 9. Molecular Pathology: Applications in Nonclinical Drug Development; 10. Infusion Toxicology and Techniques; 11. The Preparation of a Nonclinical Dossier to Support an Investigational New Drug (IND) Application and First-in-Human Clinical Trials; 12. Developmental and Reproductive Toxicology; 13. Immunotoxicology Assessment in Drug Development; 14. Juvenile Toxicity Testing to Support Clinical Trials in the Pediatric Population; 15. Photosafety: Current Methods and Future Direction; 16. Dermal Toxicology; 17. Inhalation Toxicology; 18.
|
| 505 |
0 |
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|a Nonclinical Evaluation of Carcinogenicity using the Rodent Two-Year Bioassay and Carcinogenicity Evaluations using Genetically Engineered Animals; 19 Current Strategies for Abuse Liability Assessment of New Chemical Entities; 20. Nonclinical Development of Monoclonal Antibodies; 21. Nonclinical Development of Non-Oncogenic Drugs (Small and Large Molecules); 22. Nonclinical Development of Oncology Drugs; 23. Safety Evaluation of Ocular Drugs; 24. Nonclinical toxicology of Vaccines; 25. Stem Cells In Nonclinical Toxicology; 26. Overview of the Nonclinical Development Strategies and Class-Effects of Oligonucleotide-Based Therapeutics; 27. Nonclinical Safety Assessment of Botanical Drugs; 28. Regulatory Toxicology; 29. Biostatistics for Toxicologists; 30. Role of Study Director and Study Monitor in Drug Development; 31. Use of Imaging for Nonclinical Evaluation; 32. Biomarkers in Toxicology; 33. Predictive Toxicology: Biological Assay Platforms; 34.
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| 505 |
0 |
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|a Toxicometabolomics: Technology and Applications; 35. Toxicogenomics in Nonclinical Development; 36. Nonclinical Testing of Medical Devices; 37. The Pitfalls of Drug Development
|
| 650 |
|
0 |
|a Drugs
|x Toxicology.
|
| 650 |
|
0 |
|a Drug development.
|
| 650 |
|
6 |
|a M�edicaments
|x Toxicologie.
|0 (CaQQLa)201-0007218
|
| 650 |
|
6 |
|a M�edicaments
|x D�eveloppement.
|0 (CaQQLa)201-0306620
|
| 650 |
|
7 |
|a MEDICAL
|x Pharmacology.
|2 bisacsh
|
| 650 |
|
7 |
|a Drug development
|2 fast
|0 (OCoLC)fst00898670
|
| 650 |
|
7 |
|a Drugs
|x Toxicology
|2 fast
|0 (OCoLC)fst00898958
|
| 700 |
1 |
|
|a Faqi, Ali S.,
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|t Comprehensive guide to toxicology in nonclinical drug development.
|b Second edition.
|d London, United Kingdom : Academic Press is an imprint of Elsevier, [2016]
|z 0128036206
|z 9780128036204
|w (OCoLC)942707459
|
| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128036204
|z Texto completo
|
