Chromatin regulation and dynamics /
Clasificación: | Libro Electrónico |
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Otros Autores: | |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
London, United Kingdom :
Academic Press is an imprint of Elsevier,
2016.
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Colección: | Translational epigenetics series.
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Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Cover; Title page; Copyright page; Table of Contents; List of Contributors; Preface; Chapter 1
- A Brief Introduction to Chromatin Regulation and Dynamics; 1.1
- Introduction to Basic Concepts of Chromatin Regulation; 1.2
- Epigenetic Phenomena: Heritability of Chromatin States During Cell Division; 1.2.1
- Inheritance of Stable, Cell Type-Specific Gene Expression Patterns; 1.2.2
- Genomic Imprinting; 1.2.3
- Random Monoallelic Gene Expression; 1.2.4
- Other Epigenetic Phenomena; 1.3
- Reprogramming of Epigenetic States During Development and in Diseases.
- 1.3.1
- Reprogramming of Epigenetic Marks During Early�Development1.3.2
- Epigenetic Reprogramming in Tumor Development; 1.4
- Early Period of Chromatin Research; 1.5
- Discovery of the Nucleosome and Nucleosome Positioning; 1.6
- Histone Modifications: Discovery and Function; 1.6.1
- The Language of Histone Modifications; 1.7
- Discovery of DNA Methylation: Functions and Cross Talk With Histone Modifications; 1.7.1
- Discovery of DNA Methylation; 1.7.2
- DNA Methylation in Tumor Development; 1.7.3
- Cross Talk Between DNA Methylation and Histone Modifications.
- 1.8
- Replication Timing: Potential Vehicle for Epigenetic Inheritance and Reprogramming1.9
- Chromatin Folding in 3D: Basic Principles of Genome Organization; 1.9.1
- Cross Talk Between Regulatory Elements; 1.9.2
- Technical Innovations to Detect 3D Genome Organization; 1.9.3
- Compartmentalization of Nuclear Functions; 1.10
- Signal Integration at the Level of Chromatin; 1.11
- Outlook; Abbreviations; Acknowledgments; Conflict of Interest; References; Chapter 2
- Histone Modifications and Histone Variants in Pluripotency and Differentiation.
- 2.1
- Histones and the Regulation of Transcription2.1.1
- Histones; 2.1.1.1
- Core and Linker Histones; 2.1.1.2
- Histone Variants; 2.1.2
- Histone Posttranslational Modifications; 2.1.2.1
- Histone Acetylation; 2.1.2.2
- Histone Methylation; 2.1.2.3
- Context-Dependent Role of Histone Modifications; 2.1.2.4
- Small Molecule Inhibitors of Chromatin Regulators; 2.2
- Histone PTMs and Variants During Development; 2.2.1
- Epigenetic Landscapes During Development; 2.2.2
- Histone PTMs and Variants in Pluripotency and Reprogramming; 2.2.2.1
- Unique Properties of the Chromatin of Pluripotent Cells.
- 2.2.2.2
- How is a Pluripotent Epigenetic State Established?2.2.2.3
- Histone Variants in Pluripotency; 2.2.2.4
- Histone Modifications as Barriers Against Reprogramming; 2.2.3
- Histone PTMs/Variants in Cell Specification and Differentiation in the Developing Central Nervous System; 2.2.3.1
- Histone (De)Methylation in Neural Development; 2.2.3.2
- Histone (De)Acetylation in Neural Development; 2.2.4
- Terminally Differentiated Neural Cell States: Histones in the Regulation of Functional States; 2.2.4.1
- Histone Modifiers in Synaptic Development.
- 2.2.4.2
- Histone Modifiers in Neural Plasticity, Learning, and Memory.