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Chromatin regulation and dynamics /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: G�ond�or, Anita (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London, United Kingdom : Academic Press is an imprint of Elsevier, 2016.
Colección:Translational epigenetics series.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover; Title page; Copyright page; Table of Contents; List of Contributors; Preface; Chapter 1
  • A Brief Introduction to Chromatin Regulation and Dynamics; 1.1
  • Introduction to Basic Concepts of Chromatin Regulation; 1.2
  • Epigenetic Phenomena: Heritability of Chromatin States During Cell Division; 1.2.1
  • Inheritance of Stable, Cell Type-Specific Gene Expression Patterns; 1.2.2
  • Genomic Imprinting; 1.2.3
  • Random Monoallelic Gene Expression; 1.2.4
  • Other Epigenetic Phenomena; 1.3
  • Reprogramming of Epigenetic States During Development and in Diseases.
  • 1.3.1
  • Reprogramming of Epigenetic Marks During Early�Development1.3.2
  • Epigenetic Reprogramming in Tumor Development; 1.4
  • Early Period of Chromatin Research; 1.5
  • Discovery of the Nucleosome and Nucleosome Positioning; 1.6
  • Histone Modifications: Discovery and Function; 1.6.1
  • The Language of Histone Modifications; 1.7
  • Discovery of DNA Methylation: Functions and Cross Talk With Histone Modifications; 1.7.1
  • Discovery of DNA Methylation; 1.7.2
  • DNA Methylation in Tumor Development; 1.7.3
  • Cross Talk Between DNA Methylation and Histone Modifications.
  • 1.8
  • Replication Timing: Potential Vehicle for Epigenetic Inheritance and Reprogramming1.9
  • Chromatin Folding in 3D: Basic Principles of Genome Organization; 1.9.1
  • Cross Talk Between Regulatory Elements; 1.9.2
  • Technical Innovations to Detect 3D Genome Organization; 1.9.3
  • Compartmentalization of Nuclear Functions; 1.10
  • Signal Integration at the Level of Chromatin; 1.11
  • Outlook; Abbreviations; Acknowledgments; Conflict of Interest; References; Chapter 2
  • Histone Modifications and Histone Variants in Pluripotency and Differentiation.
  • 2.1
  • Histones and the Regulation of Transcription2.1.1
  • Histones; 2.1.1.1
  • Core and Linker Histones; 2.1.1.2
  • Histone Variants; 2.1.2
  • Histone Posttranslational Modifications; 2.1.2.1
  • Histone Acetylation; 2.1.2.2
  • Histone Methylation; 2.1.2.3
  • Context-Dependent Role of Histone Modifications; 2.1.2.4
  • Small Molecule Inhibitors of Chromatin Regulators; 2.2
  • Histone PTMs and Variants During Development; 2.2.1
  • Epigenetic Landscapes During Development; 2.2.2
  • Histone PTMs and Variants in Pluripotency and Reprogramming; 2.2.2.1
  • Unique Properties of the Chromatin of Pluripotent Cells.
  • 2.2.2.2
  • How is a Pluripotent Epigenetic State Established?2.2.2.3
  • Histone Variants in Pluripotency; 2.2.2.4
  • Histone Modifications as Barriers Against Reprogramming; 2.2.3
  • Histone PTMs/Variants in Cell Specification and Differentiation in the Developing Central Nervous System; 2.2.3.1
  • Histone (De)Methylation in Neural Development; 2.2.3.2
  • Histone (De)Acetylation in Neural Development; 2.2.4
  • Terminally Differentiated Neural Cell States: Histones in the Regulation of Functional States; 2.2.4.1
  • Histone Modifiers in Synaptic Development.
  • 2.2.4.2
  • Histone Modifiers in Neural Plasticity, Learning, and Memory.