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161007s2017 ne ob 001 0 eng d |
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|a Micro- and nanotechnology in vaccine development /
|c edited by Mariusz Skwarczynski, Istvan Toth.
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|a Amsterdam :
|b Elsevier,
|c [2017]
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264 |
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|c �2017
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300 |
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|a 1 online resource (xviii, 441 pages)
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336 |
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|a text
|b txt
|2 rdacontent
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|a computer
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|2 rdamedia
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|a online resource
|b cr
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1 |
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|a Micro & nano technologies series
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588 |
0 |
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|a Online resource; title from PDF title page (EBSCO, viewed October 31, 2016).
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504 |
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|a Includes bibliographical references and index.
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|a Cover; Title page; Copyright page; Contents; List of Contributors; Introduction; Chapter One -- The Growing Influence of Nanotechnology in Our Lives; 1.1 -- Nanomaterials and Fabrication Techniques; 1.1.1 -- Nanoparticles; 1.1.2 -- Nanowires; 1.1.3 -- Nanofilms; 1.2 -- Nanomaterials in Modern Life; 1.2.1 -- Zero-dimensional nanostructures; 1.2.2 -- One-dimensional nanostructures; 1.2.3 -- Two-dimensional nanostructures; 1.3 -- Conclusions; References; Chapter Two -- Nanotechnology in Medical Research; 2.1 -- Introduction; 2.2 -- Diagnostic Nanoparticles; 2.2.1 -- Imaging agents.
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|a 2.2.1.1 -- Contrast Agents for MRI2.2.1.2 -- Contrast Agents for CT; 2.2.1.3 -- PET and SPECT Tracers; 2.2.1.4 -- Optical Imaging Agents; 2.2.1.5 -- Ultrasound Imaging Agents; 2.2.1.6 -- Photoacoustic Contrast Agents; 2.2.2 -- Nanoparticle biosensors; 2.2.2.1 -- Sensing of Biomarkers; 2.2.2.2 -- Sensing of Infectious Diseases; 2.3 -- Therapeutic Nanoparticles; 2.3.1 -- Delivery systems and therapeutics; 2.3.2 -- Drug loading; 2.3.3 -- Targeted nanoparticles; 2.4 -- Multimodal Nanoparticles; 2.4.1 -- Multimodal imaging agents; 2.4.2 -- Theranostics; 2.4.3 -- Personalized multimodal therapy.
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|a 2.5 -- In DevelopmentReferences; Chapter Three -- Introduction to Vaccines and Vaccination; 3.1 -- Introduction to Vaccines and Vaccination; 3.1.1 -- A brief history of vaccines and vaccination; 3.1.2 -- The rationale behind vaccination; 3.1.3 -- Vaccine subtypes; 3.1.4 -- Immunization sites and devices; 3.1.4.1 -- Intramuscular Immunizations; 3.1.4.2 -- Subcutaneous Immunizations; 3.1.4.3 -- Cutaneous Immunizations; 3.1.4.4 -- Mucosal Immunizations; 3.2 -- Challenges; 3.3 -- Conclusions; References; Chapter Four -- Overview of the Immune System; 4.1 -- A Short History of Immunology.
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|a 4.2 -- Immune Responses to Infection4.3 -- Innate Immunity; 4.4 -- Induced Innate Immune System; 4.4.1 -- Phagocytes; 4.4.2 -- Pattern recognition by innate immune cells; 4.4.3 -- Dendritic cells; 4.4.4 -- Natural killer cells; 4.4.5 -- Mast cells and basophils; 4.5 -- The Adaptive Immune System; 4.6 -- Cells of the Adaptive Immune System; 4.6.1 -- T cells; 4.6.2 -- B cells; 4.6.3 -- Immunological memory; 4.7 -- Immunoglobulin Classes and Function; 4.8 -- Blurring the Lines Between Innate and Adaptive Immunity; 4.8.1 -- Innate-like lymphocytes; 4.8.2 -- Innate immune cells with memory.
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|a 4.9 -- Concluding RemarksReferences; Chapter Five -- The Role of Antigen Presentation and Innate Immunity During Immune Induction by Particulate Antigens; 5.1 -- Introduction to Vaccine Adjuvants; 5.2 -- The Innate Immune System as a Regulator of Adaptive Immunity; 5.2.1 -- The relationship between innate and adaptive immune systems; 5.2.2 -- Pattern recognition receptors and their ligands; 5.3 -- Nanoparticle Vaccine Delivery Systems; 5.3.1 -- Antigens attached to inert nanoparticles; 5.3.2 -- Particulate antigens containing innate immune stimulators.
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|a 5.4 -- Targeting APCs at the Site of Vaccination and in the Draining Lymph Node.
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520 |
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|a This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress.
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650 |
|
0 |
|a Vaccines
|x Biotechnology.
|
650 |
|
0 |
|a Nanomedicine.
|
650 |
|
2 |
|a Vaccines
|x pharmacology
|0 (DNLM)D014612Q000494
|
650 |
|
2 |
|a Nanomedicine
|0 (DNLM)D050997
|
650 |
|
6 |
|a Vaccins
|x Biotechnologie.
|0 (CaQQLa)201-0226740
|
650 |
|
6 |
|a Nanom�edecine.
|0 (CaQQLa)201-0448752
|
650 |
|
7 |
|a MEDICAL
|x Pharmacology.
|2 bisacsh
|
650 |
|
7 |
|a Nanomedicine
|2 fast
|0 (OCoLC)fst01744350
|
650 |
|
7 |
|a Vaccines
|x Biotechnology
|2 fast
|0 (OCoLC)fst01163574
|
700 |
1 |
|
|a Skwarczynski, Mariusz,
|e editor.
|
700 |
1 |
|
|a Toth, Istvan,
|e editor.
|
776 |
0 |
8 |
|i Print version:
|t Micro- and nanotechnology in vaccine development.
|d Amsterdam : Elsevier, [2017]
|z 0323399819
|z 9780323399814
|w (OCoLC)949750284
|
830 |
|
0 |
|a Micro & nano technologies.
|
856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780323399814
|z Texto completo
|