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Micro- and nanotechnology in vaccine development /

This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Skwarczynski, Mariusz (Editor ), Toth, Istvan (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam : Elsevier, [2017]
Colección:Micro & nano technologies.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Micro- and nanotechnology in vaccine development /  |c edited by Mariusz Skwarczynski, Istvan Toth. 
264 1 |a Amsterdam :  |b Elsevier,  |c [2017] 
264 4 |c �2017 
300 |a 1 online resource (xviii, 441 pages) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Micro & nano technologies series 
588 0 |a Online resource; title from PDF title page (EBSCO, viewed October 31, 2016). 
504 |a Includes bibliographical references and index. 
505 0 |a Cover; Title page; Copyright page; Contents; List of Contributors; Introduction; Chapter One -- The Growing Influence of Nanotechnology in Our Lives; 1.1 -- Nanomaterials and Fabrication Techniques; 1.1.1 -- Nanoparticles; 1.1.2 -- Nanowires; 1.1.3 -- Nanofilms; 1.2 -- Nanomaterials in Modern Life; 1.2.1 -- Zero-dimensional nanostructures; 1.2.2 -- One-dimensional nanostructures; 1.2.3 -- Two-dimensional nanostructures; 1.3 -- Conclusions; References; Chapter Two -- Nanotechnology in Medical Research; 2.1 -- Introduction; 2.2 -- Diagnostic Nanoparticles; 2.2.1 -- Imaging agents. 
505 8 |a 2.2.1.1 -- Contrast Agents for MRI2.2.1.2 -- Contrast Agents for CT; 2.2.1.3 -- PET and SPECT Tracers; 2.2.1.4 -- Optical Imaging Agents; 2.2.1.5 -- Ultrasound Imaging Agents; 2.2.1.6 -- Photoacoustic Contrast Agents; 2.2.2 -- Nanoparticle biosensors; 2.2.2.1 -- Sensing of Biomarkers; 2.2.2.2 -- Sensing of Infectious Diseases; 2.3 -- Therapeutic Nanoparticles; 2.3.1 -- Delivery systems and therapeutics; 2.3.2 -- Drug loading; 2.3.3 -- Targeted nanoparticles; 2.4 -- Multimodal Nanoparticles; 2.4.1 -- Multimodal imaging agents; 2.4.2 -- Theranostics; 2.4.3 -- Personalized multimodal therapy. 
505 8 |a 2.5 -- In DevelopmentReferences; Chapter Three -- Introduction to Vaccines and Vaccination; 3.1 -- Introduction to Vaccines and Vaccination; 3.1.1 -- A brief history of vaccines and vaccination; 3.1.2 -- The rationale behind vaccination; 3.1.3 -- Vaccine subtypes; 3.1.4 -- Immunization sites and devices; 3.1.4.1 -- Intramuscular Immunizations; 3.1.4.2 -- Subcutaneous Immunizations; 3.1.4.3 -- Cutaneous Immunizations; 3.1.4.4 -- Mucosal Immunizations; 3.2 -- Challenges; 3.3 -- Conclusions; References; Chapter Four -- Overview of the Immune System; 4.1 -- A Short History of Immunology. 
505 8 |a 4.2 -- Immune Responses to Infection4.3 -- Innate Immunity; 4.4 -- Induced Innate Immune System; 4.4.1 -- Phagocytes; 4.4.2 -- Pattern recognition by innate immune cells; 4.4.3 -- Dendritic cells; 4.4.4 -- Natural killer cells; 4.4.5 -- Mast cells and basophils; 4.5 -- The Adaptive Immune System; 4.6 -- Cells of the Adaptive Immune System; 4.6.1 -- T cells; 4.6.2 -- B cells; 4.6.3 -- Immunological memory; 4.7 -- Immunoglobulin Classes and Function; 4.8 -- Blurring the Lines Between Innate and Adaptive Immunity; 4.8.1 -- Innate-like lymphocytes; 4.8.2 -- Innate immune cells with memory. 
505 8 |a 4.9 -- Concluding RemarksReferences; Chapter Five -- The Role of Antigen Presentation and Innate Immunity During Immune Induction by Particulate Antigens; 5.1 -- Introduction to Vaccine Adjuvants; 5.2 -- The Innate Immune System as a Regulator of Adaptive Immunity; 5.2.1 -- The relationship between innate and adaptive immune systems; 5.2.2 -- Pattern recognition receptors and their ligands; 5.3 -- Nanoparticle Vaccine Delivery Systems; 5.3.1 -- Antigens attached to inert nanoparticles; 5.3.2 -- Particulate antigens containing innate immune stimulators. 
505 8 |a 5.4 -- Targeting APCs at the Site of Vaccination and in the Draining Lymph Node. 
520 |a This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress. 
650 0 |a Vaccines  |x Biotechnology. 
650 0 |a Nanomedicine. 
650 2 |a Vaccines  |x pharmacology  |0 (DNLM)D014612Q000494 
650 2 |a Nanomedicine  |0 (DNLM)D050997 
650 6 |a Vaccins  |x Biotechnologie.  |0 (CaQQLa)201-0226740 
650 6 |a Nanom�edecine.  |0 (CaQQLa)201-0448752 
650 7 |a MEDICAL  |x Pharmacology.  |2 bisacsh 
650 7 |a Nanomedicine  |2 fast  |0 (OCoLC)fst01744350 
650 7 |a Vaccines  |x Biotechnology  |2 fast  |0 (OCoLC)fst01163574 
700 1 |a Skwarczynski, Mariusz,  |e editor. 
700 1 |a Toth, Istvan,  |e editor. 
776 0 8 |i Print version:  |t Micro- and nanotechnology in vaccine development.  |d Amsterdam : Elsevier, [2017]  |z 0323399819  |z 9780323399814  |w (OCoLC)949750284 
830 0 |a Micro & nano technologies. 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780323399814  |z Texto completo