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|a New therapeutics for traumatic brain injury :
|b prevention of secondary brain damage and enhancement of repair and regeneration /
|c edited by Kim A. Heidenreich.
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|a London :
|b Academic Press is an imprint of Elsevier,
|c [2017]
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|c �2017
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|a 1 online resource (xxv, 325 pages) :
|b illustrations (some color)
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|a text
|b txt
|2 rdacontent
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|a text file
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|a Includes bibliographical references and index.
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|t Part I: Interventional therapies for TBI previously or currently in phase 3 clinical trials. Why did the phase III clinical trials for progesterone in TBI fail? An analysis of three potentially critical factors /
|r D.G. Stein, R.B. Howard, I. Sayeed --
|t Hypothermia for traumatic brain injury: current evidence and future directions /
|r H. Mtaweh, D. Simon, M.J. Bell --
|t The future of TBI: hyperbaric oxygen as a primary therapeutic approach /
|r B. Miskin, L.A. Fox --
|t Part II: Repurposing FDA approved drugs for TBI treatment. Erythropoietin and its derivatives: mechanisms of neuroprotection and challenges in clinical translation /
|r T. Bogoslovsky, J.D. Bernstock, K. Kenney, C. Moore, R. Diaz-Arrastia --
|t Atorvastatin in the treatment of traumatic brain injury /
|r A.N. Sen, S.P. Gopinath, C.S. Robertson --
|t The application of glibenclamide in traumatic brain injury /
|r D.S. Hersh, J.M. Simard, H.M. Eisenberg --
|t Perispinal etanercept for traumatic brain injury /
|r E. Tobinick, H. Rodriguez-Romanacce, R. Kinssies, N. Kim --
|t Part III: Interventional drugs for TBI in phase 1-2 clinical trials. Nitric oxide synthase inhibitors in traumatic brain injury /
|r R. Schinzel, F. Tegtmeier --
|t Management of paroxysmal sympathetic hyperactivity after traumatic brain injury /
|r L.D. Wilson, T.C. Leath, M.B. Patel --
|t Part IV: Interventional drugs for TBI in preclinical development. The use of estrogen for the treatment of traumatic brain injury /
|r W.J. Hubbard, I.H. Chaudry --
|t Voltage-gated calcium channel blockers for the treatment of traumatic brain injury /
|r G.G. Gurkoff, K. Shahlaie, B.G. Lyeth, R.F. Berman --
|t 5-lipoxygenase-activating protein inhibitors: promising drugs for treating acute and chronic neuroinflammation following brain injury /
|r K.A. Heidenreich, C.E. Corser-Jensen --
|t Carbonyl scavenging as an antioxidant neuroprotective strategy for acute traumatic brain injury /
|r J.E. Cebak, I.N. Singh, J.A. Wang, R.L. Hill, J.R. Kulbe, E.D. Hall --
|t TrkB receptor agonist 7,8-Dihydroxyflavone and its therapeutic potential for traumatic brain injury /
|r J. Romeika, M. Wurzelmann, D. Sun --
|t Ceftriaxone treatment of TBI /
|r M.Q. Hameed, A. Rotenberg --
|t Part V: Drugs for TBI rehabilitation. Memantine: a safe and tolerable NMDA antagonist with potential benefits in traumatic brain injury /
|r M.A. Keiski --
|t Interventional drugs for TBI Rehabilitation of cognitive impairment: the cholinesterase inhibitor rivastigmine /
|r M.A. Hernandez-Tejada, O. Brawman-Mintzer --
|t Docosahexaenoic acid and omega 3 fatty acids /
|r M.E. Schober --
|t Treatment of mood disorders following traumatic brain injury /
|r H.L. Lin, R.E. Jorge
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|a "New Therapeutics for Traumatic Brain Injury: Prevention of Secondary Brain Damage and Enhancement of Repair and Regeneration explores traumatic brain injury (TBI), a major cause of death and disability throughout the world. The delayed nature of the secondary injury phase suggests that there is a therapeutic window for pharmacological interventions or other approaches to prevent progressive tissue damage and improve functional outcomes. It is now apparent that therapeutic interventions should entail both protective and repair/regeneration strategies depending on the phase of brain injury. This book describes emerging experimental strategies for the treatment of TBI, including new anti-inflammatory or anti-apoptotic therapeutics that limit brain damage, and novel or repurposed drugs that enhance repair or regeneration of the brain after injury"--Publisher's description
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|a Online resource; title from electronic title page (ScienceDirect viewed March 27, 2018).
|
650 |
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|a Brain damage
|x Treatment.
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650 |
|
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|a Brain damage
|x Rehabilitation.
|
650 |
|
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|a Brain
|x Wounds and injuries
|x Complications.
|
650 |
1 |
2 |
|a Brain Injuries, Traumatic
|x drug therapy
|0 (DNLM)D000070642Q000188
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650 |
1 |
2 |
|a Brain Injuries, Traumatic
|x complications
|0 (DNLM)D000070642Q000150
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650 |
2 |
2 |
|a Brain
|x drug effects
|0 (DNLM)D001921Q000187
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650 |
2 |
2 |
|a Clinical Trials as Topic
|0 (DNLM)D002986
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650 |
|
6 |
|a Cerveau
|0 (CaQQLa)201-0011413
|x L�esions et blessures
|0 (CaQQLa)201-0011413
|x Traitement.
|0 (CaQQLa)201-0377521
|
650 |
|
6 |
|a Cerveau
|x L�esions et blessures
|x Complications et s�equelles.
|0 (CaQQLa)201-0272348
|
650 |
|
7 |
|a MEDICAL
|x Neurology.
|2 bisacsh
|
650 |
|
7 |
|a Brain damage
|x Treatment.
|2 fast
|0 (OCoLC)fst00837745
|
650 |
|
7 |
|a Brain
|x Wounds and injuries
|x Complications.
|2 fast
|0 (OCoLC)fst00837695
|
650 |
|
7 |
|a Brain damage
|x Rehabilitation.
|2 fast
|0 (OCoLC)fst00837740
|
655 |
|
4 |
|a Internet Resources.
|
700 |
1 |
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|a Heidenreich, Kim A.,
|e editor.
|
776 |
0 |
8 |
|i Print version:
|t New therapeutics for traumatic brain injury.
|d Amsterdam ; Boston : Elsevier/Academic Press, [2017]
|z 9780128026861
|w (DLC) 2016942110
|w (OCoLC)971597802
|
856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128026861
|z Texto completo
|