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Insights into enzyme mechanisms and functions from experimental and computational methods /

Insights into Enzyme Mechanisms and Functions from Experimental and Computational Methods is the latest volume in the popular Advances in Protein Chemistry and Structural Biology series, an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Christov, Christo (Senior lecturer in computational biochemistry) (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cambridge, MA : Academic Press is an imprint of Elsevier, 2016.
Colección:Advances in protein chemistry and structural biology ; v. 105.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Insights into enzyme mechanisms and functions from experimental and computational methods /  |c edited by Christo Z. Christov. 
264 1 |a Cambridge, MA :  |b Academic Press is an imprint of Elsevier,  |c 2016. 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
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490 1 |a Advances in protein chemistry and structural biology ;  |v volume 105 
520 |a Insights into Enzyme Mechanisms and Functions from Experimental and Computational Methods is the latest volume in the popular Advances in Protein Chemistry and Structural Biology series, an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics. 
500 |a Includes index. 
588 0 |a Online resource; title from PDF title page (ScienceDirect, viewed September 1, 2016). 
505 0 |a Title page; Table of Contents; Copyright; Contributors; Preface; Chapter One: Molecular Modeling and Chemoinformatics to Advance the Development of Modulators of Epigenetic Targets: A Focus on DNA Methyltransferases; Abstract; 1 Introduction; 2 Progress on Chemical Information; 3 Chemoinformatic Studies of DNMTs; 4 VS: Hit Identification and Optimization; 5 Computer-Assisted Drug Repurposing; 6 Food Chemicals as Potential Modulators of DNMTs and Other Epigenetic Targets; 7 Concluding Remarks; Acknowledgments. 
505 8 |a Chapter Two: Recent Advances in Computational Models for the Study of Protein-Peptide InteractionsAbstract; 1 Introduction; 2 Theory and Methods; 3 Sample Applications; 4 Concluding Remarks; Chapter Three: Structural Plasticity in Globins: Role of Protein Dynamics in Defining Ligand Migration Pathways; Abstract; 1 Introduction; 2 Ligand Migration Pathways in the Globin Superfamily: Structure-Function Relationships; 3 The Coordination of the Heme Group and Its Role in Ligand Binding; 4 Conclusions; Acknowledgments. 
505 8 |a Chapter Four: Dynamic Reorganization and Enzymatic Remodeling of Type IV Collagen at Cell-Biomaterial InterfaceAbstract; 1 Introduction; 2 Material and Methods; 3 Results and Discussion; 4 Conclusive Remarks; Chapter Five: Cytochromes P450: History, Classes, Catalytic Mechanism, and Industrial Application; Abstract; 1 Background and History of Cytochromes P450; 2 P450 Classes; 3 P450 Family Nomenclature; 4 Catalytic Cycle; 5 Uncoupling; 6 P450s in Industry; Chapter Six: Understanding the Multifaceted Role of Human Down Syndrome Kinase DYRK1A; Abstract; 1 Introduction. 
505 8 |a 2 Minibrain in Drosophila3 Role of DYRK1A in Infection and Immunity; 4 Cardiovascular Function of DYRK1A; 5 Role of DYRK1A in Cancer; 6 Understanding the Neuronal Function of DYRK1A; 7 Concluding Remarks; Author Index; Subject Index. 
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700 1 |a Christov, Christo  |c (Senior lecturer in computational biochemistry),  |e editor. 
830 0 |a Advances in protein chemistry and structural biology ;  |v v. 105. 
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