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|a 9780128033135
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|z 9780128033128
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|a 2016 J-254
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|a HEA
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|a 616.1
|2 23
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| 245 |
0 |
0 |
|a Cardiovascular diseases :
|b genetic susceptibility, environmental factors and their interaction /
|c edited by Nikolaos Papageorgiou.
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| 260 |
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|a London, United Kingdom :
|b Academic Press,
|c 2016.
|
| 300 |
|
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|a 1 online resource (254)
|
| 336 |
|
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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0 |
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|a Print version record.
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| 505 |
0 |
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|a Front Cover; Cardiovascular Diseases; Cardiovascular Diseases: Genetic Susceptibility, Environmental Factors and their Interaction; Copyright; Dedication; Contents; List of Contributors; Acknowledgments; 1 -- Summary ; 2 -- Atherosclerosis and Coronary Artery Disease: From Basics to Genetics ; INTRODUCTION; NORMAL ARTERY STRUCTURES; PATHOGENESIS OF ATHEROSCLEROSIS; INITIATION OF ATHEROMA; The Role of Endothelium; The Role of LDL Particles; The Role of Inflammation; Monocyte-Derived Macrophages; LDL and Inflammation; Atheroprotective Mechanisms and Inflammation; Retention of Macrophages.
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| 505 |
8 |
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|a T LymphocytesTHE FORMATION OF ATHEROSCLEROTIC PLAQUE; Apoptosis and Efferocytosis of Macrophages; The Role of Vascular Smooth Muscle Cells; Neovascularization; CLINICAL IMPLICATIONS OF ATHEROSCLEROSIS; GENETICS OF CORONARY ARTERY DISEASE; ABO Blood Groups; Lipid-Associated Genes; Other Atherosclerosis-Related Genes; The Role of microRNAs; ATHEROSCLEROSIS: THERAPEUTIC OPTIONS; REFERENCES; 3 -- The Role of Genetics in Acute Coronary Syndrome ; INTRODUCTION; CLOPIDOGREL; Metabolism and Pharmacokinetics; Absorption and Role of P-glycoprotein; Hepatic Carboxylation and Oxidation.
|
| 505 |
8 |
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|a Effect of Genotypic PolymorphismsABCB1; CYP2C19; Nomenclature; CYP2C19*2 and Other Loss-of-Function Alleles; Pharmacokinetics/Pharmacodynamics; Clinical Trials and Meta-analyses; CYP2C19*17 Gain of Function Allele; Incidence of CYP2C19 Alleles in Specific Ethnic Groups; CYP3A4; CYP1A2; Paraoxonase 1; CYP4F2; Platelet Surface Receptors; P2Y12 Receptor; Platelet Endothelial Aggregation Receptor-1; Protease Activated Receptors; Nongenetic Factors; Clopidogrel and Proton Pump Inhibitors; PRASUGREL; Metabolism; Pharmacokinetics, Pharmacodynamics, and Clinical Trials; TICAGRELOR; Metabolism.
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| 505 |
8 |
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|a Pharmacokinetics, Pharmacodynamics, and Clinical TrialsCompliance; Drug-Drug Interactions; GENOTYPING ASSAYS; COST-EFFECTIVENESS OF GENOTYPING; GENETIC POLYMORPHISMS RELATED TO ASPIRIN; FUTURE DIRECTIONS; Cilostazol and Role of Genetics; Statins and the Role of Genetics; SUMMARY: ROLE OF GENOTYPING IN ACUTE CORONARY SYNDROME; REFERENCES; 4 -- Global Epidemiology and Incidence of Cardiovascular Disease ; INTRODUCTION; GLOBAL BURDEN OF DISEASE: REPORTING METRICS; MEASURING THE GLOBAL BURDEN OF CARDIOVASCULAR DISEASE; Limitations of the Quality and Completeness of Data.
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| 505 |
8 |
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|a CHANGES IN TOTAL DISEASE BURDEN VERSUS CVDGLOBAL CARDIOVASCULAR MORTALITY; Global CVD Mortality Rates by WHO Region; Global CVD Mortality Rates by WHO/World Bank Region; Age and Gender Global CVD Mortality Rates; GLOBAL CARDIOVASCULAR DALY; Global CVD Lost DALYs Within WHO Regions; Global CVD Lost DALYs by WHO/World Bank Region; Age and Gender Global CVD Loss of DALYs; RISK FACTORS FOR CVD GLOBALLY; Hypertension; Diabetes Mellitus; Tobacco; Dyslipidemia; Physical Activity; Alcohol Consumption; EPIDEMIOLOGICAL TRANSITION; AGING POPULATION; ETHNICITY; European; Chinese; South Asian; Hispanic.
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| 504 |
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|a Includes bibliographical references and index.
|
| 650 |
|
0 |
|a Cardiovascular system
|x Diseases.
|
| 650 |
|
0 |
|a Cardiovascular system
|x Diseases
|x Genetic aspects.
|
| 650 |
1 |
2 |
|a Cardiovascular Diseases
|x genetics
|0 (DNLM)D002318Q000235
|
| 650 |
1 |
2 |
|a Cardiovascular Diseases
|x etiology
|0 (DNLM)D002318Q000209
|
| 650 |
|
2 |
|a Cardiovascular Diseases
|0 (DNLM)D002318
|
| 650 |
2 |
2 |
|a Genetic Predisposition to Disease
|0 (DNLM)D020022
|
| 650 |
2 |
2 |
|a Environment
|0 (DNLM)D004777
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| 650 |
|
6 |
|a Appareil cardiovasculaire
|x Maladies.
|0 (CaQQLa)201-0057760
|
| 650 |
|
6 |
|a Appareil cardiovasculaire
|0 (CaQQLa)201-0057760
|x Maladies
|0 (CaQQLa)201-0057760
|x Aspect g�en�etique.
|0 (CaQQLa)201-0377534
|
| 650 |
|
7 |
|a HEALTH & FITNESS
|x Diseases
|x General.
|2 bisacsh
|
| 650 |
|
7 |
|a MEDICAL
|x Clinical Medicine.
|2 bisacsh
|
| 650 |
|
7 |
|a MEDICAL
|x Diseases.
|2 bisacsh
|
| 650 |
|
7 |
|a MEDICAL
|x Evidence-Based Medicine.
|2 bisacsh
|
| 650 |
|
7 |
|a MEDICAL
|x Internal Medicine.
|2 bisacsh
|
| 650 |
|
7 |
|a Cardiovascular system
|x Diseases
|2 fast
|0 (OCoLC)fst00847181
|
| 650 |
|
7 |
|a Cardiovascular system
|x Diseases
|x Genetic aspects
|2 fast
|0 (OCoLC)fst00847194
|
| 700 |
1 |
|
|a Papageorgiou, Nikolaos.
|
| 776 |
0 |
8 |
|i Print version:
|t Cardiovascular diseases.
|d London, United Kingdom : Academic Press, 2016
|z 9780128033128
|z 0128033126
|w (OCoLC)900032389
|
| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128033128
|z Texto completo
|
