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020 |a 0128051477  |q (electronic bk.) 
020 |a 9780128051474  |q (electronic bk.) 
020 |z 9780128048320 
020 |z 0128048328 
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072 7 |a MED  |x 014000  |2 bisacsh 
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072 7 |a MED  |x 045000  |2 bisacsh 
082 0 4 |a 616.8/3104  |2 23 
100 1 |a Khan, T. K. 
245 1 0 |a Biomarkers in Alzheimer's disease /  |c T.K. Khan. 
260 |a London, United Kingdom :  |b Academic Press :  |b Elsevier,  |c 2016. 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
588 0 |a Print version record. 
505 0 |a Cover ; Title page; Copyright page; Contents; Foreword; Preface; Acknowledgments; Chapter 1 -- Introduction to Alzheimer's Disease Biomarkers ; 1.1 -- Historical Background; 1.2 -- Important Events in Alzheimer's Disease (AD) Research; 1.3 -- Some Facts About Alzheimer's Disease; 1.4 -- Common Features of Alzheimer's Disease; 1.5 -- Classification of Alzheimer's Disease; 1.6 -- Risk Factors for Alzheimer's Disease; 1.7 -- Definition of a Biomarker; 1.7.1 -- A. Categorization of Biomarkers According to Their Role. 
505 8 |a 1.7.2 -- B. Definition of Common Statistical Parameters to Quantify the Performance of Biomarkers1.8 -- Biomarkers of Alzheimer's Disease; 1.9 -- Future Focus: Detecting Preclinical Stages of Alzheimer's Disease; 1.10 -- Economic Impact of Alzheimer's Disease Biomarkers; 1.11 -- Conclusions; Bibliography; Chapter 2 -- Clinical Diagnosis of Alzheimer's Disease ; 2.1 -- Clinical Diagnosis of Alzheimer's Disease: Historical Perspective; 2.2 -- Neuropsychological Assessment Tests to Diagnose Alzheimer's Disease; 2.2.1 -- Mini-Mental State Examination; 2.2.2 -- Clock Drawing Test. 
505 8 |a 2.2.3 -- Alzheimer's Disease Assessment Scale2.2.4 -- Neuropsychological Test Battery; 2.2.4.1 -- Other neuropsychological tests; 2.2.5 -- Clinical Dementia Rating; 2.2.6 -- Global Deterioration Scale; 2.2.7 -- Dementia Severity Rating Scale; 2.3 -- Neuropathology at Brain Autopsy to Diagnose Alzheimer's Disease; 2.4 -- Accuracy of Clinical Diagnosis of Alzheimer's Disease; 2.5 -- Alzheimer's Disease-Related Neurological Conditions; 2.5.1 -- Preclinical Alzheimer's Disease; 2.5.2 -- Mild Cognitive Impairment; 2.5.3 -- Non-Alzheimer's Dementias; 2.5.3.1 -- Vascular dementia; 2.5.3.2 -- Lewy body dementia. 
505 8 |a 2.5.3.3 -- Frontotemporal dementia2.5.3.4 -- Creutzfeldt-Jacob disease; 2.5.3.5 -- Other non-AD dementias; 2.6 -- Challenges in Diagnosing Alzheimer's Disease; 2.6.1 -- Long Prodromal Stages; 2.6.2 -- Comorbidity With Non-Alzheimer's Disease Dementias; 2.6.3 -- Multiple Nongenetic and Genetic Factors; 2.6.4 -- Anomalous Alzheimer's Disease Neuropathology; 2.7 -- Comprehensive Alzheimer's Disease Diagnostic Framework; 2.8 -- Conclusions; Bibliography; Chapter 3 -- Neuroimaging Biomarkers in Alzheimer's Disease ; 3.1 -- Neuroimaging in Alzheimer's Disease; 3.1.1 -- Structural Neuroimaging. 
505 8 |a 3.1.2 -- Functional Neuroimaging3.1.3 -- Molecular Neuroimaging; 3.2 -- Common Neuroimaging Alzheimer's Disease Biomarkers and Modalities; 3.3 -- Magnetic Resonance Imaging; 3.3.1 -- Structural MRI; 3.3.2 -- Functional MRI; 3.3.3 -- Magnetic Resonance Spectroscopy; 3.3.4 -- Advanced Magnetic Resonance Based Neuroimaging Modalities; 3.3.4.1 -- Diffusion tensor imaging; 3.3.4.2 -- Arterial spin labeling MRI; 3.3.4.3 -- Task free fMRI; 3.4 -- Positron Emission Tomography; 3.4.1 -- Amyloid Imaging by PET; 3.4.2 -- Glucose Metabolism Measurement by PET; 3.4.3 -- Brain Inflammation Imaging by PET. 
505 8 |a 3.4.4 -- Tau Imaging by PET. 
500 |a Includes index. 
504 |a Includes bibliographical references and index. 
650 0 |a Alzheimer's disease  |x Molecular aspects. 
650 0 |a Biochemical markers. 
650 2 |a Alzheimer Disease  |x diagnosis  |0 (DNLM)D000544Q000175 
650 2 |a Biomarkers  |0 (DNLM)D015415 
650 6 |a Maladie d'Alzheimer  |0 (CaQQLa)201-0114128  |x Aspect mol�eculaire.  |0 (CaQQLa)201-0374959 
650 6 |a Marqueurs biologiques.  |0 (CaQQLa)201-0177920 
650 7 |a HEALTH & FITNESS  |x Diseases  |x General.  |2 bisacsh 
650 7 |a MEDICAL  |x Clinical Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Diseases.  |2 bisacsh 
650 7 |a MEDICAL  |x Evidence-Based Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Internal Medicine.  |2 bisacsh 
650 7 |a Alzheimer's disease  |x Molecular aspects  |2 fast  |0 (OCoLC)fst00806550 
650 7 |a Biochemical markers  |2 fast  |0 (OCoLC)fst00831950 
776 0 8 |i Erscheint auch als:  |n Druck-Ausgabe  |t Khan, Tapan. Biomarkers in Alzheimer's Disease 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780128048320  |z Texto completo