Genomics, circuits, and pathways in clinical neuropsychiatry /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Lehner, Thomas (Thomas A.) (Editor ), Miller, Bruce L., 1949- (Editor ), State, Matthew W. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: [London, UK] : Academic Press is an imprint of Elsevier, 2016.
Temas:
Neuropsychiatry.
Neuropsychiatry
Neuropsychiatrie.
HEALTH & FITNESS / Diseases / General
MEDICAL / Clinical Medicine
MEDICAL / Diseases
MEDICAL / Evidence-Based Medicine
MEDICAL / Internal Medicine
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Machine generated contents note: 1.The Newly Emerging View of the Genome
  • Introduction / Christopher E. Mason / Stephan J. Sanders
  • Conceptualizing DNA / Christopher E. Mason / Stephan J. Sanders
  • Information Flow in Biological Systems / Christopher E. Mason / Stephan J. Sanders
  • Key Definitions / Christopher E. Mason / Stephan J. Sanders
  • Cis and Trans / Christopher E. Mason / Stephan J. Sanders
  • Gene / Christopher E. Mason / Stephan J. Sanders
  • Transcript / Christopher E. Mason / Stephan J. Sanders
  • High-Throughput Sequencing / Christopher E. Mason / Stephan J. Sanders
  • The Genome (DNA) / Christopher E. Mason / Stephan J. Sanders
  • Visualizing the Genome / Christopher E. Mason / Stephan J. Sanders
  • Large-Scale Structures in the Genome / Christopher E. Mason / Stephan J. Sanders
  • Telomeres / Christopher E. Mason / Stephan J. Sanders
  • Subtelomeres / Christopher E. Mason / Stephan J. Sanders
  • Centromeres / Christopher E. Mason / Stephan J. Sanders
  • Note continued: Small-Scale Structures in the Genome / Christopher E. Mason / Stephan J. Sanders
  • Protein-Coding Genes / Christopher E. Mason / Stephan J. Sanders
  • Noncoding Transcripts/Genes / Christopher E. Mason / Stephan J. Sanders
  • Enhancers / Christopher E. Mason / Stephan J. Sanders
  • Silencers / Christopher E. Mason / Stephan J. Sanders
  • Insulators / Christopher E. Mason / Stephan J. Sanders
  • Repetitive Elements / Christopher E. Mason / Stephan J. Sanders
  • Multiple Roles / Christopher E. Mason / Stephan J. Sanders
  • Variation in the Genome / Christopher E. Mason / Stephan J. Sanders
  • Entire Chromosomes / Christopher E. Mason / Stephan J. Sanders
  • Structural Variation / Christopher E. Mason / Stephan J. Sanders
  • Insertions and Deletions / Christopher E. Mason / Stephan J. Sanders
  • Single-Nucleotide Variants / Christopher E. Mason / Stephan J. Sanders
  • Loss-of-Function Variants / Christopher E. Mason / Stephan J. Sanders
  • Note continued: Ethnicity and Population Frequency of Variants in the Genome / Christopher E. Mason / Stephan J. Sanders
  • Variation in Complex and Mendelian Disorders / Christopher E. Mason / Stephan J. Sanders
  • Chromatin (DNA, RNA, and Protein) and Epigenetics / Christopher E. Mason / Stephan J. Sanders
  • Chromatin State / Christopher E. Mason / Stephan J. Sanders
  • Heterochromatin / Christopher E. Mason / Stephan J. Sanders
  • Euchromatin / Christopher E. Mason / Stephan J. Sanders
  • DNA Methylation / Christopher E. Mason / Stephan J. Sanders
  • Histone Proteins / Christopher E. Mason / Stephan J. Sanders
  • Chromatin Remodelers / Christopher E. Mason / Stephan J. Sanders
  • Transcription Factors / Christopher E. Mason / Stephan J. Sanders
  • Cofactors / Christopher E. Mason / Stephan J. Sanders
  • Elongation Factors / Christopher E. Mason / Stephan J. Sanders
  • Cohesins / Christopher E. Mason / Stephan J. Sanders
  • Note continued: Regulatory Complexes / Christopher E. Mason / Stephan J. Sanders
  • Preinitiation Complex (PIC) / Stephan J. Sanders / Christopher E. Mason
  • Proximal Promoter-Pausing Complexes / Christopher E. Mason / Stephan J. Sanders
  • Elongation Complex / Christopher E. Mason / Stephan J. Sanders
  • Transcription (RNA) / Christopher E. Mason / Stephan J. Sanders
  • Posttranscriptional mRNA Modifications / Christopher E. Mason / Stephan J. Sanders
  • Epitranscriptome / Christopher E. Mason / Stephan J. Sanders
  • RNA Editing / Christopher E. Mason / Stephan J. Sanders
  • RNA Processing / Christopher E. Mason / Stephan J. Sanders
  • Translation / Christopher E. Mason / Stephan J. Sanders
  • Posttranslational Modifications / Christopher E. Mason / Stephan J. Sanders
  • Summary / Christopher E. Mason / Stephan J. Sanders
  • References / Christopher E. Mason / Stephan J. Sanders
  • Note continued: 2.Contribution of Genetic Epidemiology to Our Understanding of Psychiatric Disorders / Christopher E. Mason / Stephan J. Sanders
  • Introduction / Alison K. Merikangas / Kathleen R. Merikangas
  • Background: Epidemiology / Alison K. Merikangas / Kathleen R. Merikangas
  • Contributions to Psychiatry / Alison K. Merikangas / Kathleen R. Merikangas
  • Genetic Epidemiology / Alison K. Merikangas / Kathleen R. Merikangas
  • Family Studies / Alison K. Merikangas / Kathleen R. Merikangas
  • Twin Studies / Alison K. Merikangas / Kathleen R. Merikangas
  • Adoption Studies / Alison K. Merikangas / Kathleen R. Merikangas
  • Genetic Epidemiology of Psychiatric Disorders / Alison K. Merikangas / Kathleen R. Merikangas
  • Neurodevelopmental Disorders / Alison K. Merikangas / Kathleen R. Merikangas
  • Eating Disorders / Alison K. Merikangas / Kathleen R. Merikangas
  • Mood Disorders / Alison K. Merikangas / Kathleen R. Merikangas
  • Note continued: Anxiety Disorders: Panic Disorder / Alison K. Merikangas / Kathleen R. Merikangas
  • Obsessive-Compulsive Disorder / Alison K. Merikangas / Kathleen R. Merikangas
  • Substance Use Disorders / Alison K. Merikangas / Kathleen R. Merikangas
  • Summary / Alison K. Merikangas / Kathleen R. Merikangas
  • Applications of Genetic Epidemiology in Molecular Era / Alison K. Merikangas / Kathleen R. Merikangas
  • Study Designs and Samples / Alison K. Merikangas / Kathleen R. Merikangas
  • Statistical Approaches to Estimate Genetic Influence / Alison K. Merikangas / Kathleen R. Merikangas
  • Phenotypes: Moving Beyond Dichotomous Classification / Alison K. Merikangas / Kathleen R. Merikangas
  • Incorporation of Environmental Factors / Alison K. Merikangas / Kathleen R. Merikangas
  • Combining Genetic and Environmental Factors / Alison K. Merikangas / Kathleen R. Merikangas
  • Team Science / Alison K. Merikangas / Kathleen R. Merikangas
  • Note continued: References / Alison K. Merikangas / Kathleen R. Merikangas
  • 3.Natural Selection and Neuropsychiatric Disease: Theory, Observation, and Emerging Genetic Findings / Alison K. Merikangas / Kathleen R. Merikangas
  • Introduction / Mark J. Daly / Benjamin M. Neale / Elise B. Robinson
  • Epidemiology of Neuropsychiatric Disease / Mark J. Daly / Benjamin M. Neale / Elise B. Robinson
  • Theoretical Considerations / Mark J. Daly / Benjamin M. Neale / Elise B. Robinson
  • Hypothesis Testing: Epidemiology and Emerging Genetic Data / Mark J. Daly / Benjamin M. Neale / Elise B. Robinson
  • Mendelian Randomization and Polygenic Risk / Mark J. Daly / Benjamin M. Neale / Elise B. Robinson
  • De Novo Mutation and Mutation-Selection Balance / Mark J. Daly / Benjamin M. Neale / Elise B. Robinson
  • Conclusions / Mark J. Daly / Benjamin M. Neale / Elise B. Robinson
  • References / Mark J. Daly / Benjamin M. Neale / Elise B. Robinson
  • Note continued: 4.Genome Tools and Methods: Rare Genetic Variation / Mark J. Daly / Benjamin M. Neale / Elise B. Robinson
  • Rare Variants in Psychiatric Disease / Jonathan Sebat / Daniel J. Barrera
  • Genetic Variation / Daniel J. Barrera / Jonathan Sebat
  • Modern Technologies for Discovery of Rare Variants / Jonathan Sebat / Daniel J. Barrera
  • Microarray Technology and Large-Scale Copy Number Variants in Neurodevelopmental and Neuropsychiatric Disease / Jonathan Sebat / Daniel J. Barrera
  • Copy Number Variant Studies of Disease / Jonathan Sebat / Daniel J. Barrera
  • Studies of De Novo Mutation in Trio Families / Jonathan Sebat / Daniel J. Barrera
  • Case-Control Studies / Jonathan Sebat / Daniel J. Barrera
  • Analysis Strategies / Daniel J. Barrera / Jonathan Sebat
  • Genome / Daniel J. Barrera / Jonathan Sebat
  • Pathways / Daniel J. Barrera / Jonathan Sebat
  • Genes / Daniel J. Barrera / Jonathan Sebat
  • SNVs / Daniel J. Barrera / Jonathan Sebat
  • Note continued: Detection of Rare Genetic Variation by High-Throughput Sequencing / Daniel J. Barrera / Jonathan Sebat
  • Exome / Daniel J. Barrera / Jonathan Sebat
  • Gene Panels / Daniel J. Barrera / Jonathan Sebat
  • Whole Genome Sequencing / Daniel J. Barrera / Jonathan Sebat
  • Rare Genetic Variation in Noncoding DNA: A New Frontier / Daniel J. Barrera / Jonathan Sebat
  • Rare Genetic Variants and the Potential to Affect Clinical Care / Daniel J. Barrera / Jonathan Sebat
  • References / Daniel J. Barrera / Jonathan Sebat
  • 5.Neuroepigenomics and Human Disease / Daniel J. Barrera / Jonathan Sebat
  • Epigenetics / John M. Greally / Eric J. Nestler
  • Epigenetics in Neurobiological Research / John M. Greally / Eric J. Nestler
  • The Genomic Context of Transcriptional and Epigenetic Mechanisms / John M. Greally / Eric J. Nestler
  • Transcriptional and Epigenetic Regulatory Mechanisms / John M. Greally / Eric J. Nestler
  • Note continued: Epigenetic Perturbation and Epigenome-Wide Assays / John M. Greally / Eric J. Nestler
  • Cell Type Choices in Neuroepigenomic Studies / John M. Greally / Eric J. Nestler
  • Interaction of the Genome With the Epigenome / John M. Greally / Eric J. Nestler
  • Epigenetics Mechanisms of Brain Diseases: General Principles and Future Directions / John M. Greally / Eric J. Nestler
  • References / Eric J. Nestler / John M. Greally
  • 6.Bioinformatics in Neuropsychiatric Genomics / John M. Greally / Eric J. Nestler
  • What is Bioinformatics? / Shaun M. Purcell
  • Databases / Shaun M. Purcell
  • Methods / Shaun M. Purcell
  • Tools / Shaun M. Purcell
  • Standards / Shaun M. Purcell
  • Summary / Shaun M. Purcell
  • List of URLs / Shaun M. Purcell
  • Core Genomic Databases and Portals / Shaun M. Purcell
  • Genome Browsers / Shaun M. Purcell
  • Genetic Variation / Shaun M. Purcell
  • Gene Expression Resources / Shaun M. Purcell
  • Note continued: Programming Environments for Bioinformatics / Shaun M. Purcell
  • Genetic Linkage, Association, and Variation Detection / Shaun M. Purcell
  • Network and Pathway Analysis / Shaun M. Purcell
  • Rare Variant Detection and Annotation / Shaun M. Purcell
  • Identifiers, Ontologies, and Standards / Shaun M. Purcell
  • Psychiatric/Neuroscience Projects / Shaun M. Purcell
  • References / Shaun M. Purcell
  • 7.Imaging Genomics And Enigma / Shaun M. Purcell
  • Introduction / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Power of MRI / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • What Is Imaging Genomics? / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • The Endophenotype Concept and Biomarkers / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Mapping Brain Diseases in Neurology / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Note continued: MRI Versus Cellular Measures / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Mapping Brain Disorders: Psychiatry / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Psychiatric Neuroimaging Expands Worldwide / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Meta-Analysis / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • ENIGMA Studies of Brain Disease / Neda Jahanshad / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein
  • Defusing Controversy With Meta-Analysis / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Imaging Genomics and Genome-Wide Association Studies / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Genetic Influences on the Brain / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Genes and Disease Risk / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Note continued: Manhattan Plots / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Candidate Genes and Genome-Wide Association Studies / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Genome-Wide Significance / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Formation of ENIGMA in 2009 / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Surprises From Imaging Genomics Consortia / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Other Neuroimaging Methods / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Multivariate Imaging Genomics and Big Data / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Searching the Brain for Gene Effects / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Cooperative Machine Learning / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Note continued: Conclusions / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Acknowledgments / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • References / Neda Jahanshad / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein
  • 8.Brain in a Dish: Stem Cell Technologies to Study Disorders of the Central Nervous System / Paul M. Thompson / Derrek P. Hibar / Jason L. Stein / Neda Jahanshad
  • Generating Induced Pluripotent Stem Cells / Cleber A. Trujillo / Priscilla D. Negraes / Branka Hrvoj-Mihic / Mauro F.C. Lins / Katerina Semendeferi / Alysson R. Muotri
  • Progress in Modeling Human Central Nervous System Pathology: Neurodevelopmental Disorders / Cleber A. Trujillo / Priscilla D. Negraes / Branka Hrvoj-Mihic / Mauro F.C. Lins / Katerina Semendeferi / Alysson R. Muotri
  • Rett Syndrome / Cleber A. Trujillo / Priscilla D. Negraes / Branka Hrvoj-Mihic / Mauro F.C. Lins / Katerina Semendeferi / Alysson R. Muotri
  • Note continued: Fragile X Syndrome / Cleber A. Trujillo / Priscilla D. Negraes / Branka Hrvoj-Mihic / Mauro F.C. Lins / Katerina Semendeferi / Alysson R. Muotri
  • Angelman Syndrome / Cleber A. Trujillo / Priscilla D. Negraes / Branka Hrvoj-Mihic / Mauro F.C. Lins / Katerina Semendeferi / Alysson R. Muotri
  • Timothy Syndrome / Cleber A. Trujillo / Priscilla D. Negraes / Branka Hrvoj-Mihic / Mauro F.C. Lins / Katerina Semendeferi / Alysson R. Muotri
  • Contribution of Different Cell Types to Neurodevelopmental Disorders / Cleber A. Trujillo / Priscilla D. Negraes / Branka Hrvoj-Mihic / Mauro F.C. Lins / Katerina Semendeferi / Alysson R. Muotri
  • The Next Step of Induced Pluripotent Stem Cells: Three-Dimensional Cultures and Mini-Brains / Cleber A. Trujillo / Priscilla D. Negraes / Branka Hrvoj-Mihic / Mauro F.C. Lins / Katerina Semendeferi / Alysson R. Muotri
  • Note continued: Limitations of Induced Pluripotent Stem Cell Model / Cleber A. Trujillo / Priscilla D. Negraes / Branka Hrvoj-Mihic / Mauro F.C. Lins / Katerina Semendeferi / Alysson R. Muotri
  • Genome Editing: Creating Diseased Embryonic Stem Cells / Alysson R. Muotri / Cleber A. Trujillo / Priscilla D. Negraes / Branka Hrvoj-Mihic / Mauro F.C. Lins / Katerina Semendeferi
  • Drug Discovery With Induced Pluripotent Stem Cells / Cleber A. Trujillo / Priscilla D. Negraes / Branka Hrvoj-Mihic / Mauro F.C. Lins / Katerina Semendeferi / Alysson R. Muotri
  • Conclusions / Cleber A. Trujillo / Priscilla D. Negraes / Branka Hrvoj-Mihic / Mauro F.C. Lins / Katerina Semendeferi / Alysson R. Muotri
  • References / Cleber A. Trujillo / Priscilla D. Negraes / Branka Hrvoj-Mihic / Mauro F.C. Lins / Katerina Semendeferi / Alysson R. Muotri
  • Note continued: 9.Association Strategies / Cleber A. Trujillo / Priscilla D. Negraes / Branka Hrvoj-Mihic / Mauro F.C. Lins / Katerina Semendeferi / Alysson R. Muotri
  • Common Variants / Benjamin M. Neale
  • Rare Variants / Benjamin M. Neale
  • Conclusions / Benjamin M. Neale
  • Acknowledgments / Benjamin M. Neale
  • References / Benjamin M. Neale
  • 10.Reconstructing Causal Network Models of Human Disease / Benjamin M. Neale
  • Introduction / Eric E. Schadt
  • Modeling Biological Data / Eric E. Schadt
  • Causality as a Statistical Inference / Eric E. Schadt
  • From Assessing Causal Relationships Among Trait Pairs to Predictive Gene Networks / Eric E. Schadt
  • Building From the Bottom Up or Top Down? / Eric E. Schadt
  • An Integrative Genomics Approach to Constructive Predictive Network Models / Eric E. Schadt
  • Integrating Genetic Data as a Structure Before Enhancing Causal Inference in the Bayesian Network Reconstruction Process / Eric E. Schadt
  • Note continued: Incorporating Other -Omics Data as Network Priors in the Bayesian Network Reconstruction Process / Eric E. Schadt
  • Elucidating the Complexity of Human Disease: From the Metabolic to the Psychiatric / Eric E. Schadt
  • Application of Predictive Network Models to High-Throughput Screening / Eric E. Schadt
  • Conclusion and Future Directions / Eric E. Schadt
  • References / Eric E. Schadt
  • 11.Gene Networks in Neuropsychiatric Disease / Eric E. Schadt
  • Introduction / Neelroop N. Parikshak / Daniel H. Geschwind
  • RNA, Protein, and Epigenetic Molecular Levels in Neurobiology / Neelroop N. Parikshak / Daniel H. Geschwind
  • The Challenge of Spatial and Temporal Heterogeneity in the Central Nervous System / Neelroop N. Parikshak / Daniel H. Geschwind
  • Gene Networks Provide a Framework for Neurobiological Interpretation / Neelroop N. Parikshak / Daniel H. Geschwind
  • Note continued: Gene Networks in Neuropsychiatric Disorders / Neelroop N. Parikshak / Daniel H. Geschwind
  • Genome-Wide Approaches / Neelroop N. Parikshak / Daniel H. Geschwind
  • Seed-Based Approaches / Neelroop N. Parikshak / Daniel H. Geschwind
  • Protein-Protein Interaction Networks / Neelroop N. Parikshak / Daniel H. Geschwind
  • Integrative Network Approaches / Neelroop N. Parikshak / Daniel H. Geschwind
  • Themes From Cross-Method Comparisons / Neelroop N. Parikshak / Daniel H. Geschwind
  • Conclusions and Future Directions / Neelroop N. Parikshak / Daniel H. Geschwind
  • Acknowledgments / Neelroop N. Parikshak / Daniel H. Geschwind
  • References / Neelroop N. Parikshak / Daniel H. Geschwind
  • 12.Somatic Mosaicism and Neurological Diseases / Neelroop N. Parikshak / Daniel H. Geschwind
  • Introduction / Saumya S. Jamuar / Alissa M. D'Gama / Christopher A. Walsh
  • Note continued: Cortical Clonal Architecture and Somatic Mutations / Saumya S. Jamuar / Alissa M. D'Gama / Christopher A. Walsh
  • Somatic Mutations in Normal Brain / Saumya S. Jamuar / Alissa M. D'Gama / Christopher A. Walsh
  • Somatic Mutation in Neurological Disease / Saumya S. Jamuar / Alissa M. D'Gama / Christopher A. Walsh
  • "Brain-Only" Somatic Mutations / Saumya S. Jamuar / Alissa M. D'Gama / Christopher A. Walsh
  • "Second-Hit" Mutations Produce Mosaicism / Saumya S. Jamuar / Alissa M. D'Gama / Christopher A. Walsh
  • Neurodevelopmental Disorders Caused by Somatic Mutations / Saumya S. Jamuar / Alissa M. D'Gama / Christopher A. Walsh
  • Neurological Diseases Caused or Modulated by Somatic Mutations / Saumya S. Jamuar / Alissa M. D'Gama / Christopher A. Walsh
  • Types of Somatic Variants / Saumya S. Jamuar / Alissa M. D'Gama / Christopher A. Walsh
  • Large-Scale Chromosomal Abnormalities / Saumya S. Jamuar / Alissa M. D'Gama / Christopher A. Walsh
  • Note continued: Copy Number Variants / Saumya S. Jamuar / Alissa M. D'Gama / Christopher A. Walsh
  • Single-Nucleotide Variants / Saumya S. Jamuar / Alissa M. D'Gama / Christopher A. Walsh
  • Tissue Type Considerations / Saumya S. Jamuar / Alissa M. D'Gama / Christopher A. Walsh
  • Tools to Study Somatic Variation in the Brain / Saumya S. Jamuar / Alissa M. D'Gama / Christopher A. Walsh
  • Copy Number Variants / Saumya S. Jamuar / Alissa M. D'Gama / Christopher A. Walsh
  • Single-Nucleotide Variants, Including Insertions and Deletions / Saumya S. Jamuar / Alissa M. D'Gama / Christopher A. Walsh
  • Conclusion / Saumya S. Jamuar / Alissa M. D'Gama / Christopher A. Walsh
  • Acknowledgments / Saumya S. Jamuar / Alissa M. D'Gama / Christopher A. Walsh
  • References / Saumya S. Jamuar / Alissa M. D'Gama / Christopher A. Walsh
  • 13.The Molecular Landscape of the Developing Human Central Nervous System / Saumya S. Jamuar / Alissa M. D'Gama / Christopher A. Walsh
  • Note continued: Introduction / Nenad Sestan / Ying Zhu / John C. Silbereis / Sirisha Pochareddy / Mingfeng Li
  • The Cellular and Structural Complexity of the Human Brain / John C. Silbereis / Ying Zhu / Sirisha Pochareddy / Mingfeng Li / Nenad Sestan
  • General Principles of Human Neocortical Development / Ying Zhu / John C. Silbereis / Sirisha Pochareddy / Mingfeng Li / Nenad Sestan
  • Neurogenesis and Neuronal Migration / John C. Silbereis / Ying Zhu / Sirisha Pochareddy / Nenad Sestan / Mingfeng Li
  • Glial Cell Genesis and Differentiation / Ying Zhu / John C. Silbereis / Sirisha Pochareddy / Mingfeng Li / Nenad Sestan
  • Neural Circuit Formation and Developmental Plasticity / Ying Zhu / John C. Silbereis / Mingfeng Li / Sirisha Pochareddy / Nenad Sestan
  • Regional Patterning and Interhemispheric Lateralization / Ying Zhu / John C. Silbereis / Sirisha Pochareddy / Mingfeng Li / Nenad Sestan
  • Note continued: Transcriptional Landscape of the Developing Human Brain / Ying Zhu / John C. Silbereis / Sirisha Pochareddy / Mingfeng Li / Nenad Sestan
  • Spatiotemporal Dynamics of Human Brain Transcriptome / Ying Zhu / John C. Silbereis / Sirisha Pochareddy / Mingfeng Li / Nenad Sestan
  • Transcriptional Architecture Underlying Cellular and Regional Specification of the Human Brain / Ying Zhu / John C. Silbereis / Sirisha Pochareddy / Mingfeng Li / Nenad Sestan
  • Transcriptional Insights Into Maturational Trajectories of the Human Neocortex / Ying Zhu / John C. Silbereis / Sirisha Pochareddy / Mingfeng Li / Nenad Sestan
  • Interhemispheric Neocortical Transcriptomes / Ying Zhu / John C. Silbereis / Sirisha Pochareddy / Mingfeng Li / Nenad Sestan
  • Epigenomic and Regulatory Landscapes of the Developing Human Brain / Ying Zhu / John C. Silbereis / Sirisha Pochareddy / Mingfeng Li / Nenad Sestan
  • Note continued: DNA Methylation in Human Brain Development / Ying Zhu / John C. Silbereis / Sirisha Pochareddy / Mingfeng Li / Nenad Sestan
  • Histone Modification and Functional Regulatory Elements in Human Brain Development / Ying Zhu / John C. Silbereis / Sirisha Pochareddy / Mingfeng Li / Nenad Sestan
  • Noncoding RNAs in Human Brain Development / Ying Zhu / John C. Silbereis / Sirisha Pochareddy / Mingfeng Li / Nenad Sestan
  • Insights Into Psychiatric and Neurological Disorders / Ying Zhu / John C. Silbereis / Sirisha Pochareddy / Mingfeng Li / Nenad Sestan
  • Conclusions and Future Directions / Ying Zhu / John C. Silbereis / Sirisha Pochareddy / Mingfeng Li / Nenad Sestan
  • Acknowledgments / Ying Zhu / John C. Silbereis / Sirisha Pochareddy / Mingfeng Li / Nenad Sestan
  • References / Ying Zhu / John C. Silbereis / Sirisha Pochareddy / Mingfeng Li / Nenad Sestan
  • Note continued: 14.Optogenetic Approaches to Neural Circuit Analysis in the Mammalian Brain / Ying Zhu / John C. Silbereis / Sirisha Pochareddy / Mingfeng Li / Nenad Sestan
  • Introduction / Stephan Lammel / Gul Dolen / Robert C. Malenka
  • Tools for Functional Neural Circuit Dissection / Stephan Lammel / Gul Dolen / Robert C. Malenka
  • Definition of Opsins / Stephan Lammel / Gul Dolen / Robert C. Malenka
  • Expression of Opsins in the Mammalian Brain / Stephan Lammel / Gul Dolen / Robert C. Malenka
  • Cell Type-Specific Targeting of Opsins Using Promoters / Stephan Lammel / Gul Dolen / Robert C. Malenka
  • Cell Type-Specific Targeting of Opsins Using Cre/loxP Recombinase / Stephan Lammel / Gul Dolen / Robert C. Malenka
  • Intersectional Approaches / Stephan Lammel / Gul Dolen / Robert C. Malenka
  • Functional Circuit Analysis / Stephan Lammel / Gul Dolen / Robert C. Malenka
  • Note continued: Ex Vivo Synaptic Input Specificity / Stephan Lammel / Gul Dolen / Robert C. Malenka
  • In Vivo Neural Circuit Analysis in Freely Moving Animals / Stephan Lammel / Gul Dolen / Robert C. Malenka
  • Translational Medicine / Stephan Lammel / Gul Dolen / Robert C. Malenka
  • Conclusions / Stephan Lammel / Gul Dolen / Robert C. Malenka
  • References / Stephan Lammel / Gul Dolen / Robert C. Malenka
  • 15.Brain Imaging With Magneto-encephalography During Rest and During Speech and Language Processing / Stephan Lammel / Gul Dolen / Robert C. Malenka
  • Brain Imaging With Magnetoencephalography (MEG) / Srikantan S. Nagarajan / Kamalini G. Ranasinghe / Keith A. Vossel
  • Sensing the Brain's Magnetic Fields / Srikantan S. Nagarajan / Kamalini G. Ranasinghe / Keith A. Vossel
  • From Sensing to Imaging / Srikantan S. Nagarajan / Kamalini G. Ranasinghe / Keith A. Vossel
  • Note continued: Forward Models Describing Brain Activity and Measurements / Srikantan S. Nagarajan / Kamalini G. Ranasinghe / Keith A. Vossel
  • Inverse Models for Reconstructing Brain Activity From Measurements / Srikantan S. Nagarajan / Kamalini G. Ranasinghe / Keith A. Vossel
  • Sources of Noise in Magnetoencephalography / Srikantan S. Nagarajan / Kamalini G. Ranasinghe / Keith A. Vossel
  • Temporal and Spatial Resolution of Magnetoencephalography Imaging / Srikantan S. Nagarajan / Kamalini G. Ranasinghe / Keith A. Vossel
  • From Single-Subject Reconstructions to Group-Level Inference / Srikantan S. Nagarajan / Kamalini G. Ranasinghe / Keith A. Vossel
  • Magnetoencephalography Studies in Aging and Dementia / Srikantan S. Nagarajan / Kamalini G. Ranasinghe / Keith A. Vossel
  • Resting Magnetoencephalography Studies in Aging and Dementia / Srikantan S. Nagarajan / Kamalini G. Ranasinghe / Keith A. Vossel
  • Note continued: Activation Magnetoencephalography Studies in Aging and Dementia / Srikantan S. Nagarajan / Kamalini G. Ranasinghe / Keith A. Vossel
  • Summary and Conclusions / Srikantan S. Nagarajan / Kamalini G. Ranasinghe / Keith A. Vossel
  • References / Srikantan S. Nagarajan / Kamalini G. Ranasinghe / Keith A. Vossel
  • 16.Resting-State Functional MRI: A Novel Tool for Understanding Brain Networks in Neuropsychiatric Disorders / Srikantan S. Nagarajan / Kamalini G. Ranasinghe / Keith A. Vossel
  • A Brief History of Resting-State Functional MRI / Michael Greicius
  • Healthy Skepticism Drives Deeper Explorations / Michael Greicius
  • Attributes of Resting-State Networks / Michael Greicius
  • Default-Mode and Salience Networks / Michael Greicius
  • Applications to Brain Disease / Michael Greicius
  • Future Directions / Michael Greicius
  • References / Michael Greicius
  • 17.Neuroimaging Advances in Alzheimer's Disease / Michael Greicius
  • Note continued: Abbreviations / Daniel R. Schonhaut / Gil D. Rabinovici
  • Introduction / Daniel R. Schonhaut / Gil D. Rabinovici
  • Alzheimer's Disease Defined / Daniel R. Schonhaut / Gil D. Rabinovici
  • Imaging Characteristics of Alzheimer's Disease / Daniel R. Schonhaut / Gil D. Rabinovici
  • Structural MRI / Daniel R. Schonhaut / Gil D. Rabinovici
  • Functional MRI / Daniel R. Schonhaut / Gil D. Rabinovici
  • [18F]Fluoro-2-Deoxy-o-Glucose Positron Emission Tomography / Daniel R. Schonhaut / Gil D. Rabinovici
  • Amyloid Positron Emission Tomography / Daniel R. Schonhaut / Gil D. Rabinovici
  • Tau Positron Emission Tomography / Daniel R. Schonhaut / Gil D. Rabinovici
  • Progression of Neuroimaging Abnormalities: An Amyloid Cascade? / Daniel R. Schonhaut / Gil D. Rabinovici
  • Preclinical Alzheimer's Disease / Daniel R. Schonhaut / Gil D. Rabinovici
  • Mild Cognitive Impairment / Daniel R. Schonhaut / Gil D. Rabinovici
  • Note continued: Dementia and Limitations of the Amyloid Cascade Hypothesis / Daniel R. Schonhaut / Gil D. Rabinovici
  • Underlying Mechanisms of Alzheimer's Disease Pathology / Daniel R. Schonhaut / Gil D. Rabinovici
  • Amyloid Plaques Form in Regional Hubs / Daniel R. Schonhaut / Gil D. Rabinovici
  • Tau Spreads Through Functional Networks / Daniel R. Schonhaut / Gil D. Rabinovici
  • Conclusions / Daniel R. Schonhaut / Gil D. Rabinovici
  • References / Daniel R. Schonhaut / Gil D. Rabinovici
  • 18.Progressive Supranuclear Palsy and Related Parkinsonian Disorders / Daniel R. Schonhaut / Gil D. Rabinovici
  • Introduction / Jesse A. Brown / William W. Seeley
  • Each Neurodegenerative Syndrome Reflects a Network / Jesse A. Brown / William W. Seeley
  • Class-Wide Principles of Network-Based Neurodegeneration / Jesse A. Brown / William W. Seeley
  • Parkinsonian Syndromes: Parkinson Disease and Others / Jesse A. Brown / William W. Seeley
  • Note continued: Parkinson Disease: Clinical and Anatomical Features / Jesse A. Brown / William W. Seeley
  • Progressive Supranuclear Palsy Syndrome: Clinical Features / Jesse A. Brown / William W. Seeley
  • Corticobasal Syndrome: Clinical Features / Jesse A. Brown / William W. Seeley
  • Network Architecture of Neurodegenerative Parkinsonian Syndromes / William W. Seeley / Jesse A. Brown
  • Network Architecture of Progressive Supranuclear Palsy Syndrome / Jesse A. Brown / William W. Seeley
  • Network Architecture of Corticobasal Syndrome / Jesse A. Brown / William W. Seeley
  • Clinicopathological Correlation in Progressive Supranuclear Palsy and Corticobasal Degeneration / Jesse A. Brown / William W. Seeley
  • Multiple Proteinopathies Can Cause Progressive Supranuclear Palsy Syndrome and Corticobasal Syndrome / Jesse A. Brown / William W. Seeley
  • Pathological Causes of Progressive Supranuclear Palsy Syndrome / Jesse A. Brown / William W. Seeley
  • Note continued: Pathological Causes of Corticobasal Syndrome / Jesse A. Brown / William W. Seeley
  • Progressive Supranuclear Palsy and Corticobasal Degeneration Histopathology Can Cause Multiple Clinical Syndromes / Jesse A. Brown / William W. Seeley
  • Genetic Factors in Progressive Supranuclear Palsy and Corticobasal Degeneration / Jesse A. Brown / William W. Seeley
  • Rare Monogenic Causes / Jesse A. Brown / William W. Seeley
  • Risk Factors / Jesse A. Brown / William W. Seeley
  • Genome-Wide Association Studies / Jesse A. Brown / William W. Seeley
  • Conclusion / Jesse A. Brown / William W. Seeley
  • Acknowledgment / Jesse A. Brown / William W. Seeley
  • References / Jesse A. Brown / William W. Seeley
  • 19.A New Neuroanatomy of Basal Ganglia Circuitry / Jesse A. Brown / William W. Seeley
  • Abbreviations / Nicholas AuYong / Adrienne M. Keener / Yvette M. Bordelon / Carlos Portera-Cailliau / Nader Pouratian
  • Note continued: Anatomic Overview of Basal Ganglia / Nicholas AuYong / Adrienne M. Keener / Yvette M. Bordelon / Carlos Portera-Cailliau / Nader Pouratian
  • Clinical Basal Ganglia Disorders / Nicholas AuYong / Adrienne M. Keener / Yvette M. Bordelon / Carlos Portera-Cailliau / Nader Pouratian
  • Parkinson Disease / Nicholas AuYong / Adrienne M. Keener / Yvette M. Bordelon / Carlos Portera-Cailliau / Nader Pouratian
  • Huntington Disease / Nicholas AuYong / Adrienne M. Keener / Yvette M. Bordelon / Carlos Portera-Cailliau / Nader Pouratian
  • Classical Basal Ganglia Microanatomy / Nicholas AuYong / Adrienne M. Keener / Yvette M. Bordelon / Carlos Portera-Cailliau / Nader Pouratian
  • Probing Basal Ganglia Circuitry in Animal Models / Carlos Portera-Cailliau / Nader Pouratian / Nicholas AuYong / Adrienne M. Keener / Yvette M. Bordelon
  • Recordings in Animals / Nicholas AuYong / Adrienne M. Keener / Yvette M. Bordelon / Carlos Portera-Cailliau / Nader Pouratian
  • Note continued: Ablation Studies / Nicholas AuYong / Adrienne M. Keener / Yvette M. Bordelon / Carlos Portera-Cailliau / Nader Pouratian
  • Optogenetics / Nicholas AuYong / Adrienne M. Keener / Yvette M. Bordelon / Carlos Portera-Cailliau / Nader Pouratian
  • Animal Studies Reveal Flaws in the Classical Model of Basal Ganglia Circuitry / Nicholas AuYong / Adrienne M. Keener / Yvette M. Bordelon / Carlos Portera-Cailliau / Nader Pouratian
  • Emerging Techniques to Study Basal Ganglia Circuitry in Animals / Nicholas AuYong / Adrienne M. Keener / Yvette M. Bordelon / Carlos Portera-Cailliau / Nader Pouratian
  • Calcium Imaging / Nicholas AuYong / Adrienne M. Keener / Yvette M. Bordelon / Carlos Portera-Cailliau / Nader Pouratian
  • Voltage Sensors / Nicholas AuYong / Adrienne M. Keener / Yvette M. Bordelon / Carlos Portera-Cailliau / Nader Pouratian
  • Optogenetics / Nicholas AuYong / Adrienne M. Keener / Yvette M. Bordelon / Carlos Portera-Cailliau / Nader Pouratian
  • Note continued: Striatal Interneurons / Nicholas AuYong / Adrienne M. Keener / Yvette M. Bordelon / Carlos Portera-Cailliau / Nader Pouratian
  • Probing Basal Ganglia Circuitry in Humans: Invasive Physiology / Nicholas AuYong / Adrienne M. Keener / Yvette M. Bordelon / Carlos Portera-Cailliau / Nader Pouratian
  • Noninvasive Studies of Basal Ganglia Circuitry in Humans / Nicholas AuYong / Adrienne M. Keener / Yvette M. Bordelon / Carlos Portera-Cailliau / Nader Pouratian
  • Conclusions / Nicholas AuYong / Adrienne M. Keener / Yvette M. Bordelon / Carlos Portera-Cailliau / Nader Pouratian
  • References / Yvette M. Bordelon / Carlos Portera-Cailliau / Nader Pouratian / Nicholas AuYong / Adrienne M. Keener
  • 20.Brainstem Circuitry and Emotions / Nicholas AuYong / Adrienne M. Keener / Yvette M. Bordelon / Carlos Portera-Cailliau / Nader Pouratian
  • The Structural Organization of the Brainstem / Panos Theofilas / Helmut Heinsen / Lea T. Grinberg
  • Note continued: Reticular Formation / Panos Theofilas / Helmut Heinsen / Lea T. Grinberg
  • Chemical Properties of the Reticular Nuclei / Panos Theofilas / Helmut Heinsen / Lea T. Grinberg
  • Reticular Formation Modulates Behavior / Panos Theofilas / Helmut Heinsen / Lea T. Grinberg
  • Sleep Cycle / Panos Theofilas / Helmut Heinsen / Lea T. Grinberg
  • Mood / Panos Theofilas / Helmut Heinsen / Lea T. Grinberg
  • Conclusion / Panos Theofilas / Helmut Heinsen / Lea T. Grinberg
  • References / Panos Theofilas / Helmut Heinsen / Lea T. Grinberg
  • 21.Apathy: Frontal and Basal Ganglia Circuits / Panos Theofilas / Helmut Heinsen / Lea T. Grinberg
  • Introduction / Pongsatorn Paholpak / Mario F. Mendez
  • Definition and Diagnosis of Apathy / Pongsatorn Paholpak / Mario F. Mendez
  • Clinical Variants, Diagnosis, and Measurement of Apathy / Pongsatorn Paholpak / Mario F. Mendez
  • Measurement and Rating Scale / Pongsatorn Paholpak / Mario F. Mendez
  • Note continued: Molecular and Neuroanatomical Basis of Apathy / Pongsatorn Paholpak / Mario F. Mendez
  • Prefrontal Cortex in Primates / Pongsatorn Paholpak / Mario F. Mendez
  • Prefrontal Cortex in Humans / Pongsatorn Paholpak / Mario F. Mendez
  • Motivation and Reward System: Basal Ganglia Structures and Corticostriatal Loop / Pongsatorn Paholpak / Mario F. Mendez
  • Structural and Functional Connectivity in Apathy / Pongsatorn Paholpak / Mario F. Mendez
  • Dopamine Regulation in Motivation and Reward System / Pongsatorn Paholpak / Mario F. Mendez
  • Apathy in Neuropsychiatric Diseases / Pongsatorn Paholpak / Mario F. Mendez
  • Traumatic Brain Injury / Pongsatorn Paholpak / Mario F. Mendez
  • Schizophrenia / Pongsatorn Paholpak / Mario F. Mendez
  • Stroke / Pongsatorn Paholpak / Mario F. Mendez
  • Parkinson Disease / Mario F. Mendez / Pongsatorn Paholpak
  • Huntington Disease / Pongsatorn Paholpak / Mario F. Mendez
  • Note continued: Alzheimer Dementia / Pongsatorn Paholpak / Mario F. Mendez
  • Frontotemporal Dementia / Pongsatorn Paholpak / Mario F. Mendez
  • Genetics Studies of Apathy / Pongsatorn Paholpak / Mario F. Mendez
  • Huntington Disease / Pongsatorn Paholpak / Mario F. Mendez
  • Parkinson Disease and Parkinsonism / Pongsatorn Paholpak / Mario F. Mendez
  • Alzheimer Dementia / Pongsatorn Paholpak / Mario F. Mendez
  • Frontotemporal Dementia / Pongsatorn Paholpak / Mario F. Mendez
  • Schizophrenia / Pongsatorn Paholpak / Mario F. Mendez
  • Summary / Pongsatorn Paholpak / Mario F. Mendez
  • References / Pongsatorn Paholpak / Mario F. Mendez
  • 22.Emotional Dysfunction in Psychopathology and Neuropathology: Neural and Genetic Pathways / Pongsatorn Paholpak / Mario F. Mendez
  • Emotional Dysfunction in Psychopathology and Neuropathology: Neural and Genetic Pathways / Virginia E. Sturm / Claudia M. Haase / Robert W. Levenson
  • Note continued: Emotions and Emotional Processes Emotions: Short and Discrete / Virginia E. Sturm / Claudia M. Haase / Robert W. Levenson
  • Emotional Processes / Virginia E. Sturm / Claudia M. Haase / Robert W. Levenson
  • Emotional Reactivity / Virginia E. Sturm / Claudia M. Haase / Robert W. Levenson
  • Emotional Regulation / Virginia E. Sturm / Claudia M. Haase / Robert W. Levenson
  • Emotional Affiliation / Virginia E. Sturm / Claudia M. Haase / Robert W. Levenson
  • Emotional Functioning: Neural Pathways / Virginia E. Sturm / Claudia M. Haase / Robert W. Levenson
  • Emotional Reactivity / Virginia E. Sturm / Claudia M. Haase / Robert W. Levenson
  • Anterior Cingulate Cortex / Virginia E. Sturm / Claudia M. Haase / Robert W. Levenson
  • Amygdala / Virginia E. Sturm / Claudia M. Haase / Robert W. Levenson
  • Hypothalamus / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Brain Stem / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Note continued: Insula / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Emotion Regulation / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Ventrolateral Prefrontal Cortex / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Dorsolateral Prefrontal Cortex / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Anterior Midcingulate Cortex / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Inferior Parietal Lobe / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Emotional Affiliation / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Superior Temporal Sulcus / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Dorsomedial Prefrontal Cortex / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Ventral Striatum / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Medial Orbitofrontal Cortex / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Note continued: Septal Area / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Emotion Functioning: Genetic Pathways / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Model of the Genetic Pathway / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Emotional Reactivity / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Serotonin-Related Genes / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Other Genes / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Emotion Regulation / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Dopamine-Related Genes / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Other Genes / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Emotional Affiliation / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Oxytocin-Related Genes / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Note continued: Other Genes and Affiliation / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Neural and Genetic Pathways: Clinical Implications / Virginia E. Sturm / Claudia M. Haase / Robert W. Levenson
  • Emotional Dysfunction in Psychopathology and Neuropathology / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Emotional Reactivity / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Emotion Regulation / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Emotional Affiliation / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Emotion in Diagnosis / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Psychopathology: Diagnostic and Statistical Manual / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Psychopathology: Research Domain Criteria / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Neuropathology / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Note continued: Emotion in Treatment / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • References / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • 23.The Anatomy of Delusion / Virginia E. Sturm / Robert W. Levenson / Claudia M. Haase
  • Introduction and Definition / Georges Naasan
  • Phenomenology and Anatomy / Georges Naasan
  • The Two-Factor Hypothesis and the Role of the Right Prefrontal Cortex / Georges Naasan
  • Attention Bias and Faulty Assignment of Salience to External Stimuli: The "Aberrant Salience" Model / Georges Naasan
  • The Theory of Mind in People With Delusions / Georges Naasan
  • Content-Specific Delusions / Georges Naasan
  • Paranoid Delusions / Georges Naasan
  • The Capgras Delusion / Georges Naasan
  • Genetics / Georges Naasan
  • References / Georges Naasan
  • 24.Beyond Dopamine: The Role of the Serotonergic System and Treatments in Understanding and Treating Visual Hallucinations in Parkinson Disease / Georges Naasan
  • Note continued: Simple Versus Complex Visual Hallucinations / Andrew Evans / Ramon Mocellin / Dennis Velakoulis / Mark Walterfang
  • The Visual Pathway and Mechanisms of Disruption Leading to Visual Hallucinations / Dennis Velakoulis / Mark Walterfang / Andrew Evans / Ramon Mocellin
  • Complex Visual Hallucinations: The Role of Lesion Location / Dennis Velakoulis / Mark Walterfang / Andrew Evans / Ramon Mocellin
  • Synucleinopathy and Visual Hallucinations / Dennis Velakoulis / Mark Walterfang / Andrew Evans / Ramon Mocellin
  • The Origins of Visual Hallucinations in Parkinson Disease / Dennis Velakoulis / Mark Walterfang / Andrew Evans / Ramon Mocellin
  • The Serotonergic System and Visual Hallucinations / Dennis Velakoulis / Mark Walterfang / Andrew Evans / Ramon Mocellin
  • Anatomy of the Serotonergic System / Dennis Velakoulis / Mark Walterfang / Andrew Evans / Ramon Mocellin
  • Note continued: Psilocybin and the Serotonergic System / Dennis Velakoulis / Mark Walterfang / Andrew Evans / Ramon Mocellin
  • Parkinson Disease and the Serotonergic System / Dennis Velakoulis / Mark Walterfang / Andrew Evans / Ramon Mocellin
  • Pharmacological Interventions for Visual Hallucinations in Parkinson Disease / Dennis Velakoulis / Mark Walterfang / Andrew Evans / Ramon Mocellin
  • D2 Antagonism / Dennis Velakoulis / Mark Walterfang / Andrew Evans / Ramon Mocellin
  • Serotonin Antagonism / Dennis Velakoulis / Mark Walterfang / Andrew Evans / Ramon Mocellin
  • Summary / Dennis Velakoulis / Mark Walterfang / Andrew Evans / Ramon Mocellin
  • References / Dennis Velakoulis / Mark Walterfang / Andrew Evans / Ramon Mocellin
  • 25.Risk Overlap Between Clinical Disorders / Dennis Velakoulis / Mark Walterfang / Andrew Evans / Ramon Mocellin
  • Introduction / Patrick F. Sullivan
  • Clinical Neuroscience, Neurology, and Psychiatry / Patrick F. Sullivan

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