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Applications of time-of-flight and orbitrap mass spectrometry in environmental, food, doping, and forensic analysis /

Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis deals with the use of high-resolution mass spectrometry (MS) in the analysis of small organic molecules. Over the past few years, time-of-flight (ToF) and Orbitrap MS have both experie...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Perez, Sandra (Editor ), Eichhorn, Peter (Editor ), Barcel�o, Dami�a (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: [Place of publication not identified] : Elsevier, 2016.
Colección:Comprehensive analytical chemistry ; v. 71.
Temas:
Acceso en línea:Texto completo
Texto completo

MARC

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245 0 0 |a Applications of time-of-flight and orbitrap mass spectrometry in environmental, food, doping, and forensic analysis /  |c edited by Sandra P��erez, Peter Eichhorn and Dami�a Barcel�o. 
264 1 |a [Place of publication not identified] :  |b Elsevier,  |c 2016. 
300 |a 1 online resource 
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490 1 |a Comprehensive analytical chemistry ;  |v volume 71 
520 |a Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis deals with the use of high-resolution mass spectrometry (MS) in the analysis of small organic molecules. Over the past few years, time-of-flight (ToF) and Orbitrap MS have both experienced tremendous growth in a great number of analytical sectors and are now well established in many laboratories where high requirements are placed on analytical performance. This book gives a head-to-head comparison of these two technologies that compete directly with each other. As users with hands-on experience in both techniques, the authors provide a balanced description of the strengths and weaknesses of both techniques. In the vast majority of cases, ToF-MS and Orbitrap-MS have been used for qualitative purposes, mainly identification of discrete molecular entities such as drug metabolites or transformation products of environmental contaminants. This paradigm is now changing as quantitative capabilities are increasingly being explored, as are non-target approaches for unbiased broad-scope screening. In view of the continuous innovation of high-resolution MS instrument manufacturers in designing and developing more powerful machines, technological advances in both hardware and software are considerable, with many novel applications. This book summarizes and analyzes these trends. The compilation of selected examples from diverse analytical fields will allow the readers to discover not only the potential of high-resolution MS in their sector, but also shows advances in other fields that rely on hi-res MS. 
500 |a Includes index. 
588 0 |a Online resource; title from PDF title page (ScienceDirect, viewed June 10, 2016). 
505 0 |a Intro; Title page; Table of Contents; Advisory Board; Copyright; Contributors to Volume 71; Series Editor's Preface; Preface; Section I: Instrumentation; Section II: Target Analysis, Identification, and Suspect Screening; Section III: Nontarget Analysis; Section IV: Conclusions; Index; Chapter 1. Orbitrap Mass Spectrometry: Evolution and Applicability; Chapter 2. Advances in Time-of-Flight Mass Spectrometry; Chapter 3. Ambient Ionisation-High-Resolution Mass Spectrometry: Environmental, Food, Forensic and Doping analysis; Chapter 4. High-Resolution Mass Spectrometry in Doping Control 
505 8 |a Chapter 5. Application of LC-Time-of-Flight and Orbitrap-MS/MS for Pesticide Residues in Fruits and VegetablesChapter 6. Identification of Sildenafil Designer Analogues Found in Dietary Supplements; Chapter 7. High-Resolution Mass Spectrometry in Metabolite Identification; Chapter 8. LC-TOF-MS for the Identification of Environmental Metabolites and Degradation Products; Chapter 9. Application of Orbitrap Mass Spectrometry for the Identification of Transformation Products of Trace Organic Contaminants Formed in the Environment 
505 8 |a Chapter 10. High-Resolution Mass Spectrometry Identification of Micropollutants Transformation Products Produced During Water Disinfection With Chlorine and Related ChemicalsChapter 11. Discovery of New Emerging DBPs by High-Resolution Mass Spectrometry; Chapter 12. Suspect Screening of Pharmaceuticals and Related Bioactive Compounds, Their Metabolites and Their Transformation Products in the Aquatic Environment, Biota and Humans Using LC-HR-MS Techniques 
505 8 |a 2. Current Improvements in TOF Instrumentation3. GC/MS Instrumentation; 4. IM-TOF-MS Adding Additional Dimensionality; 5. Conclusion; 1. Introduction; 2. Ambient Ionisation Methods; 3. Ambient Mass Spectrometry Applications; 4. Concluding Remarks; 1. Introduction; 2. Targeted Analysis; 3. Untargeted Detection; 4. Conclusions; 1. Introduction; 2. Mass Resolution; 3. Mass Accuracy; 4. Workflows in Accurate Mass Spectrometry; 5. Comparison of Accurate Mass Spectrometry and Triple Quadrupole Mass Spectrometry; 6. Quantitative Analysis in Accurate Mass Spectrometry 
504 |a Includes bibliographical references and index. 
650 0 |a Time-of-flight mass spectrometry. 
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650 7 |a SCIENCE  |x Chemistry  |x Analytic.  |2 bisacsh 
650 7 |a Time-of-flight mass spectrometry  |2 fast  |0 (OCoLC)fst01151187 
700 1 |a Perez, Sandra,  |e editor. 
700 1 |a Eichhorn, Peter,  |e editor. 
700 1 |a Barcel�o, Dami�a,  |e editor. 
776 0 8 |i Print version:  |z 0444635726  |z 9780444635723  |w (OCoLC)938383126 
830 0 |a Comprehensive analytical chemistry ;  |v v. 71. 
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