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Hematopoiesis /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cambridge, MA :
Academic Press is an imprint of Elsevier,
2016.
|
| Colección: | Current topics in developmental biology ;
v. 118. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
MARC
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| 245 | 0 | 0 | |a Hematopoiesis / |c edited by Emery H. Bresnick. |
| 264 | 1 | |a Cambridge, MA : |b Academic Press is an imprint of Elsevier, |c 2016. | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Current topics in developmental biology ; |v volume 118 | |
| 588 | 0 | |a Online resource; title from PDF title page (ScienceDirect, viewed May 9, 2016). | |
| 505 | 0 | |a Front Cover; Hematopoiesis; Copyright; Contents; Contributors; Preface; Chapter One: Regulation of Blood Stem Cell Development; 1. Introduction; 1.1. HSC Generation; 1.2. Tracking Hematopoietic Cell Generation from Embryonic Endothelium; 1.3. Regulation of Hemogenic Endothelium; 1.4. Hemogenic Transcriptional Program; 1.5. Reprogramming; References; Chapter Two: Hematopoietic Stem Cell and Its Bone Marrow Niche; 1. Introduction; 2. Evolution of the Stem Cell Niche Concept; 3. Location Matters; 4. Cellular Participants in the Bone Marrow Microenvironment; 4.1. Osteolineage Cells | |
| 505 | 8 | |a 4.2. Perivascular Cells4.3. Endothelial Cells; 4.4. Adipocytes; 4.5. Macrophages; 5. The Sympathetic Nervous System; 6. HSC Mobilization from the BM Niche; 7. Niche of Hematopoietic Malignancies; 8. Perspectives; References; Chapter Three: The Hematopoietic Stem and Progenitor Cell Cistrome: GATA Factor-Dependent cis-Regulatory Mechanisms; 1. cis-Regulatory Mechanisms; 2. GATA Factor Interactions with DNA and Chromatin; 2.1. Sequence Requirements; 2.2. Genomic and Bioinformatics Analysis; 2.3. Discovery and Validation of Enhancers Controlling HSPCs | |
| 505 | 8 | |a 3. Components of Scl/TAL1 and GATA Factor Complexes at E-box-GATA Elements3.1. LMO2; 3.2. LDB1; 3.3. KLF1; 3.4. SWI/SNF Chromatin-Remodeling Complex; 3.5. Single-Stranded DNA-Binding Proteins; 4. HSPC Cistrome; 5. Perspective; References; Chapter Four: ETS Transcription Factor ETV2/ER71/Etsrp in Hematopoietic and Vascular Development; 1. Introduction; 2. Etv2 Is Transiently Expressed in the Hemangiogenic Progenitors; 3. ETV2 Is Sufficient to Induce Hematopoietic and Endothelial Cell Formation; 4. Nonredundant and Transient Role of ETV2 in Hematopoietic and Endothelial Cell Formation | |
| 505 | 8 | |a 5. ETV2, VEGF, and FLK1 in Hematopoietic and Endothelial Cell Formation6. ETV2 Regulates Hemangiogenic versus Cardiac Mesoderm Outcome; 7. ETS Hierarchy and ETS Switching Mechanisms in Hematopoietic and Vascular Development; 8. ETV2 in Definitive Hematopoietic Program and Function; 9. Regulation of Etv2 Expression; 10. Closing Thoughts and Future Directions; Acknowledgments; References; Chapter Five: Taking the Leap: Runx1 in the Formation of Blood from Endothelium; 1. The Three Waves of Blood Cell Formation; 2. The Role of Runx1 in the Formation of Embryonic Progenitors and HSCs | |
| 505 | 8 | |a 3. The Temporal Requirement for Runx1 in Hemogenic Endothelium4. Downstream Runx1 Targets That Execute the Endothelial to Hematopoietic Cell Transition; 5. Epigenetic Regulation by Runx1; 6. Cis-Acting Sequences Regulating Runx1 Transcription; 7. The Gene Regulatory Network Upstream of Runx1; 8. Signaling Pathways Regulating Runx1 Expression in the Aorta; 8.1. Notch Signaling; 8.2. Fibroblast Growth Factor and Bone Morphogenic Protein Signaling; 9. Conclusions and Future Directions; References; Chapter Six: SCL/TAL1 in Hematopoiesis and Cellular Reprogramming; 1. Introduction | |
| 504 | |a Includes bibliographical references and index. | ||
| 650 | 0 | |a Hematopoiesis. | |
| 650 | 2 | |a Hematopoiesis |0 (DNLM)D006410 | |
| 650 | 6 | |a H�ematopo�i�ese. |0 (CaQQLa)201-0005811 | |
| 650 | 7 | |a SOCIAL SCIENCE |x Anthropology |x Physical. |2 bisacsh | |
| 650 | 7 | |a Hematopoiesis |2 fast |0 (OCoLC)fst00954922 | |
| 700 | 1 | |a Bresnick, Emery H., |e editor. | |
| 776 | 0 | 8 | |i Print version: |a Bresnick, Emery. |t Hematopoiesis. |d : Elsevier Science, �2016 |z 9780128033197 |
| 830 | 0 | |a Current topics in developmental biology ; |v v. 118. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780128033197 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/00702153/118 |z Texto completo |