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Boron nitride nanotubes in nanomedicine /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Ciofani, Gianni (Editor ), Mattoli, Virgilio (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Oxford, UK : William Andrew is an imprint of Elsevier, 2016.
Colección:Micro & nano technologies.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover; Titile Page; Copyright Page; Contents; List of Contributors; Biographies; Foreword; Chapter 1
  • Introduction to boron nitride nanotubes: synthesis, properties, functionalization, and cutting; 1.1
  • Introduction; 1.2
  • Properties of BNNTs for potential biomedical applications; 1.3
  • Synthesis of BNNTs; 1.3.1
  • Chemical vapor deposition; 1.3.2
  • Ball milling; 1.3.3
  • Laser-based techniques; 1.3.4
  • Large-scale synthesis by plasma-based techniques; 1.4
  • Comparison of production rate, purity, and dispersibility of BNNTs.
  • 1.5
  • Functionalization and cutting of BNNTs for biomedical applications1.5.1
  • Noncovalent functionalization; 1.5.2
  • Covalent functionalization; 1.6
  • Summary; Acknowledgments; References; Chapter 2
  • Functionalization of boron nitride nanotubes for applications innanobiomedicine; 2.1
  • Introduction; 2.2
  • Covalent functionalization; 2.2.1
  • Nitrogen site reaction; 2.2.2
  • Boron site reaction; 2.3
  • Noncovalent functionalization; 2.3.1
  • Small molecules with aromatic groups; 2.3.2
  • Small molecules without aromatic groups; 2.3.3
  • Amino acids; 2.3.4
  • Surfactants; 2.3.5
  • Peptides.
  • 2.3.6
  • Deoxyribonucleic acids (DNA)2.3.7
  • Lipids; 2.3.8
  • Polysaccharides; 2.3.9
  • Polymers; 2.4
  • Defect reaction approach; 2.5
  • Filling BNNTs approach; 2.6
  • Conclusions and perspectives; References; Chapter 3
  • Biocompatibility evaluation of boron nitride nanotubes; 3.1
  • Introduction; 3.2
  • Common methods for evaluating in vitro biocompatibility; 3.2.1
  • Viability and cytotoxicity assays; 3.2.2
  • ROS detection; 3.2.3
  • Apoptosis and necrosis detection; 3.2.4
  • Genotoxicity assessment; 3.3
  • In vitro biocompatibility assessment; 3.4
  • In vivo biocompatibility assessment.
  • 3.5
  • Future studies and perspectives3.6
  • Conclusions; References; Chapter 4
  • Theoretical investigations of interactions between boron nitride nanotubes and drugs; 4.1
  • Introduction; 4.2
  • Density functional theory methods; 4.3
  • BNNTs/biomolecules interactions; 4.3.1
  • BNNTs and platinum-based drugs; 4.3.2
  • BNNTs and heterocyclic compound; 4.3.3
  • BNNTs and other clinically-relevant molecules; 4.3.4
  • BNNTs and amino acids; 4.4
  • Conclusions; References; Chapter 5
  • Boron nitride nanotubes as drug carriers; 5.1
  • Introduction.
  • 5.2
  • Improving the dispersibility of BNNT-based drug carriers5.2.1
  • Oxidation method; 5.2.2
  • Polymer surface modification method; 5.2.3
  • Plasma treatment; 5.2.4
  • Mesoporous silica coating method; 5.3
  • Various drug molecules loaded onto BNNT-based drug carriers; 5.3.1
  • DNA; 5.3.2
  • Proteins; 5.3.3
  • Flavin mononucleotide; 5.3.4
  • Chemotherapy drugs; 5.4
  • Interactions between BNNTs and drug molecules; 5.4.1
  • Weak interactions; 5.4.2
  • Covalent interactions; 5.5
  • Integration of multifunctional properties in BNNT-BASED drug carriers; 5.5.1
  • Targeting release; 5.5.2
  • Imaging.
  • 5.5.3
  • Acting as B carrier for boron neutron capture therapy.