Biflavanoids : chemical and pharmacological aspects /
Biflavanoids are an important class of plant metabolites offering a range of activities, good availability and relatively low toxicity. Long thought to hold possible therapeutic potential, the recent surge in interest for natural product drug discovery has further highlighted the possibility of usin...
Clasificación: | Libro Electrónico |
---|---|
Autores principales: | , |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Amsterdam, Netherlands :
Elsevier Ltd.,
2016.
|
Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Biflavanoids; Copyright Page; Contents; 1 Structural Features and Occurrence of Biflavanoids; 1.1 Introduction; 1.2 Nomenclature of Biflavanoids; 1.3 Structures of Biflavanoids; 1.4 Natural Distribution of Biflavanoids; 1.5 Conclusion; References; 2 Isolation and Identification of Biflavanoids; 2.1 Introduction; 2.2 Separation and Purification; 2.2.1 Preparative PC and TLC; 2.2.2 Column Chromatography; 2.2.3 Droplet Counter-Current Chromatography; 2.2.4 High-Pressure Liquid Chromatography; 2.3 Identification; 2.3.1 UV Spectroscopy; 2.3.2 Mass Spectrometry; 2.3.3 NMR Spectroscopy.
- 2.4 ConclusionReferences; 3 Synthesis of Biflavanoids; 3.1 Ullmann Coupling of Halogenated Flavones; 3.2 Synthesis of Biflavones via 1,12 Biphenyls; 3.3 Metal-Catalyzed Cross-Coupling of Flavones; 3.4 Wessely-Moser Rearrangements; 3.5 Phenol Oxidative Coupling of Flavones; 3.6 Ullmann Condensation With Flavone Salts; 3.7 Nucleophilic Substitution; 3.8 Dehydrogenation of Biflavanones Into Biflavones; 3.9 Hydrogenation of Biflavone Into Biflavanone; 3.10 Special Approaches for the Synthesis of Selective Biflavanoids; 3.10.1 Photoreductive Dimerization of Flavones.
- 3.10.2 Synthesis of 2,42 and 2,22 Biflavanoids Using Photoinduced Electron Transfer Reactions of Flavones With Amines3.11 Conclusion; References; 4 Biochemical Pharmacology of Biflavanoids; 4.1 General Biological Properties of Biflavanoids; 4.2 Anticancer Action of Bioflavonoids; 4.3 Antimicrobial and Antiviral Activity of Bioflavonoids; 4.4 Antiinflammatory Activity of Bioflavonoids: Cellular Mechanisms of Antiinflammatory Bioflavonoids; 4.5 Analgesic Activity of Bioflavonoids; 4.6 Antiinflammatory Activity of Synthetic Flavanoids; 4.7 Conclusion; References; Back Cover.