Analytical chemistry for assessing medication adherence /
The lack of adherence to medication is a growing public health problem worldwide and is costing many patients their good health and healthcare systems billions of dollars. A new volume in the Emerging Issues in Analytical Chemistry series, Analytical Chemistry for Assessing Medication Adherence intr...
Clasificación: | Libro Electrónico |
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Autores principales: | , |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Amsterdam :
Elsevier,
2016.
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Colección: | Emerging issues in analytical chemistry.
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Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Analytical Chemistry for Assessing Medication Adherence; Copyright Page; Contents; Biographies; Preface; Acknowledgments; 1 Medication Adherence; Introduction; What Is Medication Adherence?; Is Medication Adherence Really a Problem?; Consequences of Medication Nonadherence; Consequences for Patients; Consequences for Healthcare Systems; Medicines Wastage; Factors Affecting Medication Adherence; Patient Factors; Treatment Factors; Healthcare System Factors; Clinical Practice Guidelines for the Improvement of Medication Adherence; Methods for Assessing Medication Adherence.
- Indirect Assessment MethodsDirect Assessment Methods; Conclusions; References; 2 Opportunities and Challenges for Analytical Chemistry in the Assessment of Medication Adherence; Introduction; Opportunities; Challenges; Understanding Pharmacokinetic Effects on the Concentration of a Drug in the Bloodstream; Absorption; Distribution; Metabolism and Pharmacogenetics; Excretion; Overall Effects of ADME on Drug Levels in Blood; Movement of a Drug Through the Body; Biological Sample Matrices; Urine; Liquid Blood; Dried Blood Spot; Saliva; Hair; Sweat; Tears; Cerebrospinal Fluid; Semen.
- Vaginal FluidConclusions; References; 3 Analytical Chemistry Methods for the Assessment of Medication Adherence; Introduction; Sample Preparation; Protein Precipitation; Liquid-Liquid Extraction; Solid-Phase Extraction; Instrumental Analyses; Immunoassay (IA) Systems for Organic Active Ingredients; Enzyme-Based Assays; Fluorescence-Based Polarization Assays; Antibodies; Instrumentation; Point-of-Care Testing; Chromatography-Based Methods for Organic Active Pharmaceutical Ingredients; Chromatography Systems With Passive Detectors; GC With Flame Ionization Detection.
- Thin Layer and High-Performance Thin Layer Liquid ChromatographyHigh-Performance Liquid Chromatography With UV Detection; Mass Spectrometry and Chromatography; Mass Spectrometers As Dynamic Detectors For Chromatography Systems; Interfaces for GC-MS Systems; Interfaces for LC-MS Systems; Electrospray Ionization; Atmospheric Pressure Chemical Ionization; Mass Analysis; Low-Resolution Scanning MS-Linear Quadrupole; Low-Resolution Tandem Mass Spectrometers-Triple Quadrupole and Ion Traps; High-Resolution Mass Spectrometers-ToF and Orbitrap; Time-of-Flight (ToF) Instruments; Orbitrap.
- Data Collection and Manipulation for GC-MS and LC-MS InstrumentsComparison of MS Systems; Analytical Methods for Inorganic Active Pharmaceutical Ingredients; Flame Photometry; Ion-Selective Electrodes; Electrochemical Detection; Polymerase Chain Reaction (PCR) Analysis; Test Facilities; Instrumentation for Service Provision; References; 4 Application of Bioanalytical Methods to Assess Medication Adherence in Clinical Settings; Introduction; Cardiovascular Disease; Diabetes; Cancer; HIV/AIDS; Hepatitis C; Pain Management; Schizophrenia; Depression; Bipolar Disorder; Epilepsy; Malaria.