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Epi-Informatics : discovery and development of small molecule epigenetic drugs and probes /
Epi-Informatics: Discovery and Development of Small Molecule Epigenetic Drugs and Probes features multidisciplinary strategies with strong computational approaches that have led to the successful discovery and/or optimization of compounds that act as modulators of epigenetic targets. This book is in...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; Boston :
Academic Press/Elsevier,
[2016]
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 020 | |a 9780128028087 | ||
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| 082 | 0 | 4 | |a 615.7 |2 23 |
| 245 | 0 | 0 | |a Epi-Informatics : |b discovery and development of small molecule epigenetic drugs and probes / |c edited by Jos�e L. Medina-Franco, PhD. |
| 264 | 1 | |a Amsterdam ; |a Boston : |b Academic Press/Elsevier, |c [2016] | |
| 264 | 4 | |c �2016 | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Online resource; title from PDF title page (EBSCO, viewed March 17, 2016). | |
| 520 | |a Epi-Informatics: Discovery and Development of Small Molecule Epigenetic Drugs and Probes features multidisciplinary strategies with strong computational approaches that have led to the successful discovery and/or optimization of compounds that act as modulators of epigenetic targets. This book is intended for all those using or wanting to learn more about computational methodologies in epigenetic drug discovery, including molecular modelers, informaticians, pharmaceutical scientists, and medicinal chemists. With a better understanding of different molecular modeling and cheminformatic approaches, readers can incorporate these techniques into their own drug discovery projects that may involve chemical synthesis and medium- or high-throughput screening. In addition, this book highlights the significance of epigenetic targets to the public health for molecular modelers and chemoinformatians. The goal of this reference is to stimulate ongoing multidisciplinary research and to further improve current computational methodologies and workflows in order to accelerate the discovery and development of epi-drugs and epi-probes. | ||
| 505 | 0 | |a Front Cover; Epi-Informatics: Discovery and Development of Small Molecule Epigenetic Drugs and Probes; Copyright; Dedication; Contents; List of Contributors; Preface; 1 -- Introduction of Epigenetic Targets in Drug Discovery and Current Status of Epi-Drugs and Epi-Probes; 1. INTRODUCTION; 1.1 Current Status of Epigenetic Drugs; 1.2 Epigenetics; 1.2.1 DNA Methylation; 1.2.2 Histone Modification; 1.2.3 Noncoding RNAs; 1.3 The Genetics of Epigenetics; 1.4 Epigenomics; 1.5 Conclusions; 1.6 Perspectives; ACKNOWLEDGMENTS; REFERENCES; 2 -- Overview of Computer-Aided Drug Design for Epigenetic Targets | |
| 650 | 0 | |a Pharmacogenomics. | |
| 650 | 0 | |a Pharmaceutical industry |x Technological innovations. | |
| 650 | 0 | |a Drug development. | |
| 650 | 0 | |a Epigenetics. | |
| 650 | 6 | |a Pharmacog�enomique. |0 (CaQQLa)201-0322837 | |
| 650 | 6 | |a M�edicaments |x D�eveloppement. |0 (CaQQLa)201-0306620 | |
| 650 | 6 | |a �Epig�en�etique. |0 (CaQQLa)000270630 | |
| 650 | 7 | |a MEDICAL |x Pharmacology. |2 bisacsh | |
| 650 | 7 | |a Drug development |2 fast |0 (OCoLC)fst00898670 | |
| 650 | 7 | |a Epigenetics |2 fast |0 (OCoLC)fst01893642 | |
| 650 | 7 | |a Pharmaceutical industry |x Technological innovations |2 fast |0 (OCoLC)fst01060184 | |
| 650 | 7 | |a Pharmacogenomics |2 fast |0 (OCoLC)fst01060245 | |
| 700 | 1 | |a Medina-Franco, Jos�e L., |e editor. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780128028087 |z Texto completo |