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The innate immune response to non-infectious stressors : human and animal models /
The Innate Immune Response to Non-infectious Stressors: Human and Animal Models highlights fundamental mechanisms of stress response and important findings on how the immune system is affected, and in turn affects such a response. In addition, this book covers the crucial link between stress respons...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam :
Academic Press is an imprint of Elsevier,
[2016]
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 245 | 0 | 4 | |a The innate immune response to non-infectious stressors : |b human and animal models / |c edited by Massimo Amadori. |
| 264 | 1 | |a Amsterdam : |b Academic Press is an imprint of Elsevier, |c [2016] | |
| 264 | 4 | |c �2016 | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Online resource; title from PDF title page (EBSCO, viewed March 17, 2016). | |
| 520 | |a The Innate Immune Response to Non-infectious Stressors: Human and Animal Models highlights fundamental mechanisms of stress response and important findings on how the immune system is affected, and in turn affects such a response. In addition, this book covers the crucial link between stress response and energy metabolism, prompts a re-appraisal of some crucial issues, and helps to define research priorities in this fascinating, somehow elusive field of investigation. | ||
| 505 | 0 | |a Cover; Title Page; Copyright Page; Dedication; Contents; Contributors; Preface; References; Chapter 1 -- An Overview of the Innate Immune Response to Infectious and Noninfectious Stressors; Introduction; Recognition; PRRs and PAMPs; Toll-Like Receptors; Signaling; C-Type Lectin Receptors; Signaling; The RIG-I-Like Receptors; Signaling; NLRs and the Inflammasome; Signaling; AIM2-Like Receptors; Signaling; C-GAS and Other DNA Sensors; Signaling; RAGE; Soluble PRRs; PRR localization; DAMPs; Nucleic Acids; ATP; Uric Acid; Heat-Shock Proteins; Mitochondrial Danger Signals; HMGB1; DAMP; Chaperone. | |
| 505 | 8 | |a Secondary Danger SignalChemokine; Redox State; Degradation Products of the Extracellular Matrix; Secondary endogenous danger signals; Emerging and Homeostatic Danger Signals; Conclusions; References; Chapter 2 -- Homeostatic Inflammation as Environmental-Adaptation Strategy; Introduction; Innate immune sensors recognize various endogenous ligands including metabolites; Modulation of metabolites recognized by extracellular sensors; Modification of nucleic acid-sensing receptors; DNA and RNA are modified to be recognized or not by innate immune sensors. | |
| 505 | 8 | |a Priming effect of noninfectious inflammation on immune responseCorrelation with inflammatory and autoimmune diseases in adipose tissue; Excessive activation of nucleic acid-sensing sensors induces autoimmune diseases; Regulation of homeostatic inflammation and innate immune sensors for controlling immune system and homeostasis; References; Chapter 3 -- The Molecular Basis of the Immune Response to Stressed Cells and Tissues; Innate immune responses: receptors and ligands; Stress-mediated regulation of immune receptors and ligands: an overview. | |
| 505 | 8 | |a Transcriptional Regulation of NK-Cell Activating Ligands Modulated by Stress ResponsesPosttranscriptional Regulation of Stress-Controlled NK-Cell Activating Ligands; Translational and Posttranslational Regulation of Stress-Modulated NK-Cell Activating Ligands; Different forms of stress regulate innate immunity; Osmotic Stress; Thermal Stress; Genotoxic Stress; Oxidative Stress; Endoplasmic Reticulum Stress; Stress-Induced Senescence; Immunogenic cell death: putting all the things together; References; Chapter 4 -- Modulation of Innate Immunity by Hypoxia; Hypoxia; Hypoxia sensing. | |
| 505 | 8 | |a Hypoxia-Inducible FactorsNuclear Factor kB; Hypoxia effects on leukocytes; Myeloid Cells; Monocytes/Macrophages; Granulocytes; Dendritic Cells; Lymphoid Cells; Hypoxia, myeloid cells, and diseases; Pulmonary Hypertension (PH); Rheumatoid Arthritis; Inflammatory Bowel Disease; Atherosclerosis; Ischemia; Preeclampsia; Allergy; Cancer; Therapeutic targeting of hypoxic signaling; HIF Activators; HIF Inhibitors; Acknowledgments; References; Chapter 5 -- Metabolic Stress, Heat Shock Proteins, and Innate Immune Response; Introduction; Metabolic stress conditions; Metabolic stress and innate immunity. | |
| 650 | 0 | |a Chronic diseases. | |
| 650 | 0 | |a Immune response. | |
| 650 | 0 | |a Natural immunity. | |
| 650 | 1 | 2 | |a Chronic Disease |0 (DNLM)D002908 |
| 650 | 1 | 2 | |a Immunity, Innate |0 (DNLM)D007113 |
| 650 | 6 | |a Maladies chroniques. |0 (CaQQLa)201-0012323 | |
| 650 | 6 | |a R�eaction immunitaire. |0 (CaQQLa)201-0013536 | |
| 650 | 6 | |a Immunit�e naturelle. |0 (CaQQLa)201-0055771 | |
| 650 | 7 | |a HEALTH & FITNESS |x Diseases |x General. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Clinical Medicine. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Diseases. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Evidence-Based Medicine. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Internal Medicine. |2 bisacsh | |
| 650 | 7 | |a Natural immunity. |2 fast |0 (OCoLC)fst01034361 | |
| 650 | 7 | |a Chronic diseases. |2 fast |0 (OCoLC)fst00860072 | |
| 650 | 7 | |a Immune response. |2 fast |0 (OCoLC)fst00967867 | |
| 700 | 1 | |a Amadori, Massimo, |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Innate immune response to non-infectious stressors : human and animal models. |d Amsterdam, [Netherlands] : Academic Press, �2016 |h xxvii, 247 pages |z 9780128019689 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780128019689 |z Texto completo |