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Hsp90 in Cancer : Beyond the Usual Suspects /
This title focuses on the multifunctional molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of client proteins and discusses some of the lesser-known aspects of how Hsp90 and its related family members enable oncogenic transformation and ma...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cambridge, MA :
Academic Press is an imprint of Elsevier,
2016.
|
| Colección: | Advances in cancer research ;
129. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Unusual suspects in the twilight zone between the Hsp90 interactome and carcinogenesis / Evangelia Vartholomaiou, Pablo C. Echeverr�ia and Didier Picard
- Impact of posttranslational modifications on the anticancer activity of Hsp90 inhibitors / Mark R. Woodford, Diana Dunn, Jonelle B. Miller, Sami Jamal, Len Neckers and Mehdi Mollapour
- Anticancer inhibitors of Hsp90 function: beyond the usual suspects / Gaurav Garg, Anuj Khandelwal and Brian S. J. Blagg
- HSP90 in cancer: transcriptional roles in the nucleus / Stuart K. Calderwood and Len Neckers
- Hsp90 as a 'chaperone' of the epigenome: insights and opportunities for cancer therapy / Jennifer S. Isaacs
- Emerging roles of extracellular Hsp90 in cancer / Daniel Senh Wong and Daniel G. Jay
- GRP94/gp96 in cancer: biology, structure, immunology and drug development / Bill X Wu, Feng Hong, Yongliang Zhang, Ephraim Ansa-Addo and Zihai Li
- HSP90 and immune modulation in cancer / Michael W. Graner
- Hsp90: a global regulator of the genotype-to-phenotype map in cancers / Daniel Jarosz.