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Hsp90 in Cancer : Beyond the Usual Suspects /
This title focuses on the multifunctional molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of client proteins and discusses some of the lesser-known aspects of how Hsp90 and its related family members enable oncogenic transformation and ma...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cambridge, MA :
Academic Press is an imprint of Elsevier,
2016.
|
| Colección: | Advances in cancer research ;
129. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 082 | 0 | 4 | |a 616.99/4071 |2 23 |
| 245 | 0 | 0 | |a Hsp90 in Cancer : |b Beyond the Usual Suspects / |c edited by Jennifer Isaacs and Luke Whitesell. |
| 264 | 1 | |a Cambridge, MA : |b Academic Press is an imprint of Elsevier, |c 2016. | |
| 300 | |a 1 online resource (xv, 257 pages : |b illustrations (some color)). | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Advances in cancer research ; |v 129 | |
| 546 | |a Text in English. | ||
| 505 | 0 | |a Unusual suspects in the twilight zone between the Hsp90 interactome and carcinogenesis / Evangelia Vartholomaiou, Pablo C. Echeverr�ia and Didier Picard -- Impact of posttranslational modifications on the anticancer activity of Hsp90 inhibitors / Mark R. Woodford, Diana Dunn, Jonelle B. Miller, Sami Jamal, Len Neckers and Mehdi Mollapour -- Anticancer inhibitors of Hsp90 function: beyond the usual suspects / Gaurav Garg, Anuj Khandelwal and Brian S. J. Blagg -- HSP90 in cancer: transcriptional roles in the nucleus / Stuart K. Calderwood and Len Neckers -- Hsp90 as a 'chaperone' of the epigenome: insights and opportunities for cancer therapy / Jennifer S. Isaacs -- Emerging roles of extracellular Hsp90 in cancer / Daniel Senh Wong and Daniel G. Jay -- GRP94/gp96 in cancer: biology, structure, immunology and drug development / Bill X Wu, Feng Hong, Yongliang Zhang, Ephraim Ansa-Addo and Zihai Li -- HSP90 and immune modulation in cancer / Michael W. Graner -- Hsp90: a global regulator of the genotype-to-phenotype map in cancers / Daniel Jarosz. | |
| 588 | 0 | |a Online resource; title from PDF title page (ScienceDirect, viewed March 3, 2016). | |
| 504 | |a Includes bibliographical references and index. | ||
| 520 | 8 | |a This title focuses on the multifunctional molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of client proteins and discusses some of the lesser-known aspects of how Hsp90 and its related family members enable oncogenic transformation and malignant progression. |b Hsp90 in Cancer: Beyond the Usual Suspects, the latest volume in the Advances in Cancer Research series, focuses on the multifunctional molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of client proteins and discusses some of the lesser-known aspects of how Hsp90 and its related family members enable oncogenic transformation and malignant progression. | |
| 650 | 0 | |a Molecular chaperones. | |
| 650 | 0 | |a Carcinogenesis |x Molecular aspects. | |
| 650 | 1 | 2 | |a Molecular Chaperones |0 (DNLM)D018832 |
| 650 | 6 | |a Mol�ecules chaperonnes. |0 (CaQQLa)201-0249100 | |
| 650 | 6 | |a Canc�erogen�ese |x Aspect mol�eculaire. |0 (CaQQLa)201-0235786 | |
| 650 | 7 | |a HEALTH & FITNESS / Diseases / General |2 bisacsh | |
| 650 | 7 | |a MEDICAL / Clinical Medicine |2 bisacsh | |
| 650 | 7 | |a MEDICAL / Diseases |2 bisacsh | |
| 650 | 7 | |a MEDICAL / Evidence-Based Medicine |2 bisacsh | |
| 650 | 7 | |a MEDICAL / Internal Medicine |2 bisacsh | |
| 650 | 7 | |a Carcinogenesis |x Molecular aspects. |2 fast |0 (OCoLC)fst00846978 | |
| 650 | 7 | |a Molecular chaperones. |2 fast |0 (OCoLC)fst01024760 | |
| 655 | 4 | |a Internet Resources. | |
| 700 | 1 | |a Isaacs, Jennifer |c (Professor of Pharmacology), |e editor. | |
| 700 | 1 | |a Whitesell, Luke, |e editor. | |
| 830 | 0 | |a Advances in cancer research ; |v 129. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780128022900 |z Texto completo |