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|a Metabolic phenotyping in personalized and public healthcare /
|c edited by Elaine Holmes, Jeremy K. Nicholson, Ara W. Darzi, John C. Lindon.
|
264 |
|
1 |
|a Amsterdam :
|b Academic Press is an imprint of Elsevier,
|c [2016]
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264 |
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4 |
|c �2016
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300 |
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|a 1 online resource :
|b illustrations (some color)
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|a text
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|a Print version record.
|
504 |
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|a Includes bibliographical references and index.
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520 |
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|a Metabolic Phenotyping in Personalized and Public Healthcare provides information on the widespread recognition that a personalized or stratified approach to patient treatment may offer a more efficient and effective healthcare solution than phenotype-led approaches. In order to achieve that objective, a deep personal description is required at the level of the genome, proteome, metabolome, or preferably a combination of these aided by technology. This book, edited and written by the outstanding luminaries of this evolving field, evaluates metabolic profiling and its uses across personalized and population healthcare, while also covering the advent of new technology fields, such as surgical metabonomics. In addition, the text presents specific examples of where this technology has been used clinically and with efficacy, pointing towards a framework and protocol for usage as it hits the clinical mainstream.
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505 |
0 |
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|a Unmet medical needs / Hutan Ashrafian, Thanos Athanasiou, Jeremy K. Nicholson, Ara W. Darzi -- The development of metabolic phenotyping: a historical perspective / John C. Lindon and Ian D. Wilson -- Phenotyping the patient journey / Elaine Holmes, Jeremy K. Nicholson, Jin Li, and Ara W. Darzi -- Precision surgery and surgical spectroscopy / James Kinross, Laura Muirhead, and Zoltan Takats -- High-throughput metabolic screening / Anthony C. Dona -- Pharmacometabonomics and predictive metabonomics: new tools for personalized medicine / Jeremy R. Everett, John C. Lindon, and Jeremy K. Nicholson -- Population screening for biological and environmental properties of teh human metabolic phenotype: implications for personalized medicine / Douglas J. Walker, Young-Mi Go, Ken Liu, Kurt D. Pennell, and Dean P. Jones -- Handing on health to the next generation: early life exposures / Elaine Holmes, David MacIntyre, Neena Modi, and Julian R. Marchesi -- The aging superorganism / James Kinross and Julian R. Marchesi -- Phenome centers and global harmonization / Seth Chitayat and John F. Rudan -- From databases to big data / Nadine Levin, Reza M. Salek, and Christoph Steinbeck -- Modeling people and populations: exploring medical visualization through immersive interactive virtual environments / Sarah Kenderdine, Jeremy K. Nicholson, and Ingrid Mason -- Future visions for clinical metabolic phenotyping: prospects and challenges / John C. Linden, Jeremy K. Nicholson, Elaine Holmes, and Ara W. Darzi.
|
650 |
|
0 |
|a Medical genetics.
|
650 |
|
0 |
|a Metabolism
|x Disorders
|x Genetic aspects.
|
650 |
|
0 |
|a Phenotype.
|
650 |
|
0 |
|a Metabolism.
|
650 |
1 |
2 |
|a Genetics, Medical
|0 (DNLM)D005826
|
650 |
2 |
2 |
|a Metabolism
|0 (DNLM)D008660
|
650 |
2 |
2 |
|a Phenotype
|0 (DNLM)D010641
|
650 |
|
6 |
|a G�en�etique m�edicale.
|0 (CaQQLa)201-0001432
|
650 |
|
6 |
|a Troubles du m�etabolisme
|0 (CaQQLa)201-0061163
|x Aspect g�en�etique.
|0 (CaQQLa)201-0377534
|
650 |
|
6 |
|a Ph�enotypes.
|0 (CaQQLa)201-0267454
|
650 |
|
6 |
|a M�etabolisme.
|0 (CaQQLa)201-0062122
|
650 |
|
7 |
|a metabolism (biological concept)
|2 aat
|0 (CStmoGRI)aat300254909
|
650 |
|
7 |
|a HEALTH & FITNESS
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|x General.
|2 bisacsh
|
650 |
|
7 |
|a MEDICAL
|x Clinical Medicine.
|2 bisacsh
|
650 |
|
7 |
|a MEDICAL
|x Diseases.
|2 bisacsh
|
650 |
|
7 |
|a MEDICAL
|x Evidence-Based Medicine.
|2 bisacsh
|
650 |
|
7 |
|a MEDICAL
|x Internal Medicine.
|2 bisacsh
|
650 |
|
7 |
|a Metabolism
|2 fast
|0 (OCoLC)fst01017473
|
650 |
|
7 |
|a Medical genetics
|2 fast
|0 (OCoLC)fst01014133
|
650 |
|
7 |
|a Phenotype
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|0 (OCoLC)fst01060531
|
700 |
1 |
|
|a Holmes, Elaine,
|e editor.
|
700 |
1 |
|
|a Nicholson, Jeremy K.,
|e editor.
|
700 |
1 |
|
|a Darzi, Ara,
|e editor.
|
700 |
1 |
|
|a Lindon, John C.,
|e editor.
|
776 |
0 |
8 |
|i Print version:
|a Nicholson, Jeremy.
|t Metabolic Phenotyping in Personalized and Public Healthcare.
|d : Elsevier Science, �2016
|z 9780128003442
|
856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128003442
|z Texto completo
|