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Studies in natural products chemistry. Volume 47 /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Rahman, Atta-ur-, 1942- (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam : Elsevier, 2016.
Colección:Studies in natural products chemistry ; Volume 47.
Temas:
Acceso en línea:Texto completo
Texto completo
Tabla de Contenidos:
  • Cover; Title Page; Copyright Page; Contents; Contributors; Preface; Chapter 1
  • Topoisomerase I Inhibitors Derived from Natural Products: Structure-Activity Relationships and Antitumor Potency; Abbreviations; Introduction; New camptothecin derivatives; Indolocarbazoles; Evodiamine and its derivatives; Lamellarins; Wakayin and tsitsikammamine derivatives; Topopyrones; Berberines; Other natural products; Concluding remarks; References; Chapter 2
  • Isolation and Identification of Enediynes and Cycloaromatized Derivatives; Introduction; From the producing organism to the product
  • Production Media for EnediynesIsolation: the relevance of the selected bioassay; Isolation and purification of chromoprotein enediynes; Apoproteins and self-resistance; Isolation and purification of nonchromoprotein enediynes; Natural enediynes: the discovery of a new chemical entity; Macromomycin and Auromomycin; Neocarzinostatin Chromophore (3); Elucidation of the Nine-Membered Core; Kedarcidin (4); C-1027 Chromophore (5); Maduropeptin Chromophore (6); N1999A2 (2); Calicheamicins: The Discovery of 10-Membered Enediynes; Namenamicin (8); Shishijimicins (9); Esperamicins (10)
  • Dynemicin (11) and Uncialamycin (12)Artifacts and stability of nine-membered enediynes; Concluding remarks; Acknowledgments; References; Chapter 3
  • Natural Substances from Higher Plants as Potential Anti-MRSA Agents; Introduction; Methods for evaluating antimicrobial activity of plant extracts; Disc Diffusion Test; Agar Diffusion Test; Broth Dilution Test; Direct Bioautography; Vapor Phase Test; Inhibition of Biofilm Formation; Measurement of Synergy (Checkerboard, Isobole, and Time-Kill Assays); Anti-MRSA activity of honey; Honey for Wound Care; Anti-MRSA activity of propolis
  • Prospects for applying honey and propolis in clinical practiceEssential oils; In Vitro Antibacterial Activity of EOs; Mode of Action of EOs; Combination of EOs With Their Individual Components or Antibiotics; Anti-MRSA Human Studies Involving EOs; Conclusions and Future Perspectives of EOs in MRSA Infections; Overview of anti-MRSA activity of selected plant extracts, as well as their isolated compounds; Mechanism of Action of Selected Plant Extracts and Isolated Compounds and Their Synergy With Antibiotics; Conclusions and future outlook for natural compounds as anti-MRSA agents
  • AcknowledgmentReferences; Chapter 4
  • Multitargeted Bioactive Materials of Plants in the Curcuma Genus and Related Compounds: Recent Advances; Introduction; C. amada Roxb.; Generalia; Phytochemistry; Bioactivity; Overview; Antimicrobial Activity; Gastroprotective Effects; Antioxidant Activity; Anticancer Properties; Activity on Nervous System; Inhibition of Platelet Aggregation; Antiinsect Effects; C. caesia Roxb.; Generalia; Phytochemistry; Bioactivity; Overview; C. comosa Roxb.; Generalia; Phytochemistry; Bioactivity; Overview; Antiestrogenic Activity; The Question of Bioavailability