The molecular basis of drug addiction /
This volume of Progress in Molecular Biology and Translational Science focuses on the molecular basis of drug addiction.
Clasificación: | Libro Electrónico |
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Otros Autores: | |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Cambridge, MA :
Academic Press is an imprint of Elsevier,
[2016]
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Colección: | Progress in molecular biology and translational science.
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Temas: | |
Acceso en línea: | Texto completo Texto completo |
MARC
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019 | |a 939262123 | ||
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020 | |a 0128038683 |q (electronic bk.) | ||
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082 | 0 | 4 | |a 616.86 |2 23 |
245 | 0 | 4 | |a The molecular basis of drug addiction / |c edited by Shafiqur Rahman. |
264 | 1 | |a Cambridge, MA : |b Academic Press is an imprint of Elsevier, |c [2016] | |
264 | 4 | |c �2016 | |
300 | |a 1 online resource | ||
336 | |a text |b txt |2 rdacontent | ||
337 | |a computer |b c |2 rdamedia | ||
338 | |a online resource |b cr |2 rdacarrier | ||
490 | 1 | |a Progress in Molecular Biology and Translational Science ; |v v. Volume 137 | |
588 | 0 | |a Online resource; title from PDF title page (EBSCO, viewed February 11, 2016) | |
504 | |a Includes bibliographical references and index. | ||
520 | |a This volume of Progress in Molecular Biology and Translational Science focuses on the molecular basis of drug addiction. | ||
505 | 0 | |a Cover; Title page; Copyright page ; Contents ; Contributors; Preface; Chapter One -- Molecular Mechanism: ERK Signaling, Drug Addiction, and Behavioral Effects ; Abstract; 1 Introduction; 2 ERK Signaling Pathway; 3 ERK Signaling and Drug Addiction; 3.1 Cocaine; 3.2 Amphetamine; 3.3 Methamphetamine; 3.4 Marijuana; 3.5 Nicotine; 3.6 Alcohol (Ethanol); 4 Conclusions and Future Directions; Acknowledgment; References; Chapter Two -- Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings ; Abstract; 1 Alcoholism and Genetics | |
505 | 8 | |a 2 Central Glutamatergic Activity2.1 Metabotropic Glutamate Receptors ; 2.2 Ionotropic Glutamate Receptors ; 2.3 Glutamate Transporters and Carriers ; 2.4 Glutamate Synthesis and Metabolism ; 2.5 Glutamate and the Postsynaptic Density ; 3 Central Glutamate Activity and Alcohol Dependence; 3.1 Alcohol's Effects on Glutamate Activity and Extracellular Levels; 3.2 Metabotropic Glutamate Receptors and Alcohol; 3.3 Ionotropic Glutamate Receptors and Alcohol; 3.4 Glutamate Transporters/Carriers and Alcohol; 3.5 Glutamate-Associated Enzyme Activity and Alcohol | |
505 | 8 | |a 3.6 The Postsynaptic Density and Alcohol4 Glutamate-Associated Genetic Variations and Alcoholism; 5 Alcohol and Glutamate Gene Expression; 6 Alcohol-Associated Changes in Gene/Protein Expression of P Rats; 6.1 Metabotropic Glutamate Receptor Expression Differences ; 6.2 Ionotropic Glutamate Receptor Expression Differences ; 6.3 Expression Differences for Glutamate Transporters, Enzymes, and Postsynaptic Density ; 7 Conclusions; Acknowledgments; References; Chapter Three -- S-Glutathionylation and Redox Protein Signaling in Drug Addiction ; Abstract; 1 Introduction ; 2 Oxidative Stress | |
505 | 8 | |a 3 S-Glutathionylation of Proteins Occurs in Response to Oxidative Stress 4 S-Glutathionylation of Proteins is a Redox-Sensitive Signaling Mechanism in Cells ; 5 S-Glutathionylation in Addiction-Related Protein Signaling ; 5.1 Drug Addiction, Dopamine, and Oxidative Stress ; 5.2 Altered Neurotransmission in Response to Ethanol, Cocaine, and Opioids Share Common Signaling Mechanisms ; 6 S-Glutathionylation of PKA, PKC, Cdk5, and Actin May Influence Drug Behavior ; 7 S-Glutathionylation in Alcohol Addiction ; 7.1 Ethanol Metabolism Increases ROS Production | |
505 | 8 | |a 7.2 Increased ROS Production May Contribute to the Behavioral Effects of Ethanol 7.3 Protein S-Glutathionylation in Response to Ethanol ; 8 S-Glutathionylation in Cocaine Addiction ; 8.1 Cocaine Metabolism Increases ROS Production ; 8.2 Increased ROS Production May Contribute to the Behavioral Effects of Cocaine ; 8.3 Protein S-Glutathionylation in Response to Cocaine ; 9 S-Glutathionylation in Heroin Addiction ; 9.1 Heroin Metabolism Increases ROS Production ; 9.2 Increased ROS Production May Contribute to the Behavioral Effects of Heroin | |
650 | 0 | |a Substance abuse |x Physiological aspects. | |
650 | 0 | |a Drug abuse |x Molecular aspects. | |
650 | 6 | |a Polytoxicomanie |0 (CaQQLa)000347301 |x Aspect physiologique. |0 (CaQQLa)201-0374335 | |
650 | 6 | |a Toxicomanie |0 (CaQQLa)201-0014203 |x Aspect mol�eculaire. |0 (CaQQLa)201-0374959 | |
650 | 7 | |a HEALTH & FITNESS |x Diseases |x General. |2 bisacsh | |
650 | 7 | |a MEDICAL |x Clinical Medicine. |2 bisacsh | |
650 | 7 | |a MEDICAL |x Diseases. |2 bisacsh | |
650 | 7 | |a MEDICAL |x Evidence-Based Medicine. |2 bisacsh | |
650 | 7 | |a MEDICAL |x Internal Medicine. |2 bisacsh | |
650 | 7 | |a Drug abuse |x Molecular aspects |2 fast |0 (OCoLC)fst00898510 | |
650 | 7 | |a Substance abuse |x Physiological aspects |2 fast |0 (OCoLC)fst01136793 | |
700 | 1 | |a Rahman, Shafiqur, |d 1963- |e editor. | |
776 | 0 | 8 | |i Print version: |a Rahman, Shafiqur. |t Molecular Basis of Drug Addiction. |d : Elsevier Science, �2016 |z 9780128037867 |
830 | 0 | |a Progress in molecular biology and translational science. | |
856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780128037867 |z Texto completo |
856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/18771173/137 |z Texto completo |