Cargando…
The alkaloids : chemistry and biology. Volume 76 /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam :
Elsevier,
2016.
|
| Edición: | First edition. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; The Alkaloids Chemistry and Biology; Copyright; DEDICATION; Contents; CONTRIBUTORS; PREFACE; One
- Sarpagan-Ajmalan-Type Indoles: Biosynthesis, Structural Biology, and Chemo-Enzymatic Significance; 1. INTRODUCTION; 2. RAUVOLFIA ALKALOIDS-SOURCES, THERAPEUTIC VALUE, AND ENZYME DETECTION; 2.1 Choosing an Efficient Biological System; 2.2 The Alkaloid Pattern of Rauvolfia Cell Cultures; 2.3 Chemical Syntheses of Biosynthetic Intermediates; 2.4 Detection of Enzyme Activities and Enzyme Purification; 3. ENZYMES OF THE AJMALINE PATHWAY (AP); 3.1 Strictosidine Synthase (STR)
- 4.3.2 Raucaffricine Glucosidase (RG)4.3.3 Perakine Reductase (PR); 4.4 Side Routes Beyond Perakine and Raucaffrinoline; 4.5 The Route Beyond Ajmaline; 4.5.1 Side Route: From Ajmaline to Raumaclines; 4.5.2 Biosynthesis of Raumaclines; 4.5.3 Dialdehyde Reductase; 5. MONITORING BIOCONVERSIONS BY IN VIVO NMR; 6. CHEMO-ENZYMATIC APPROACHES; 6.1 From Single to Bunch-From Strictosidine Synthase (STR) to Novel Alkaloids; 6.2 Chemo-Enzymatic Application of Raucaffricine Glucosidase (RG); 7. SUMMARY; ACKNOWLEDGMENTS; REFERENCES; Two
- Sarpagine and Related Alkaloids; 1. INTRODUCTION; 1.1 Classification
- 1.2 Biosynthesis2. OCCURRENCE; 2.1 Recently Isolated Sarpagine-Related Indole Alkaloids; 3. SPECTROSCOPY; 3.1 1H NMR Spectroscopy; 3.2 13C NMR Spectroscopy; 4. PHARMACOLOGY; 5. SYNTHESIS; 5.1 The Asymmetric Pictet-Spengler Reaction; 5.2 Synthesis of Sarpagine/Macroline-Related Indole Alkaloids; 5.2.1 The Enantiospecific Total Synthesis of (+)-Vellosimine (161) by Wang; 5.2.2 A Biomimetic Total Synthesis of (+)-Na-Methylvellosimine (168) by Martin et al.; 5.2.3 Synthesis of (+)-Na-Methyl-16-Epi-Pericyclivine (180)